Results 51 to 60 of about 8,480 (219)
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies [PDF]
, 2006 The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are not immunogenic.
Varshney, Grish C. +3 more
core +1 more source
Frontiers in Nutrition, 2022 The common carbamate insecticide aldicarb is considered one of the most acutely toxic pesticides. Herein, rational design was used to synthesize two haptens with spacers of different carbon chain lengths. The haptens were then used to immunize mice.
Hong Shen +20 more
doaj +1 more source
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Food Safety and Health, EarlyView.This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu +5 more
wiley +1 more source
NEW STEROID HAPTENS FOR RADIOIMMUNOASSAY - SYNTHESIS OF STEROIDS SUBSTITUTED WITH THIOETHER OR ESTER LINKAGES AT THE 2-ALPHA-POSITION [PDF]
, 1991 Haptens with bridge at the 2-position have not yet been explored. Radioimmunoassays with antibodies directed against 2-alpha-alkyl bridged steroid haptens are expected to be highly specific due to greater topographical exposure and similarity in ...
DESAI, UR, TRIVEDI, GK
core +1 more source
Strategies for enhancing sensitivity in lateral flow assays
VIEW, EarlyView.Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed +3 more
wiley +1 more source
Frontiers in Toxicology, 2022 The immunological response in contact hypersensitivity is incited by small electrophilic compounds, known as haptens, that react with endogenous proteins after skin absorption. However, the identity of hapten-modified proteins seen as immunogenic remains
Lorena Ndreu +3 more
doaj +1 more source
Immunogenicity of Liposomal Model Membranes Sensitized with Spin-Labeled Haptens and Topographical Distribution of Haptens on the Membranes1 [PDF]
, 1982 The relation between the in vitro immunogenicity of phosphatidylcholine liposomes containing 2,4-dinitrophenyl-6-Ar-aminocaproy]phosphatidylethanolamine (DNP-Cap-PE) as a hapten and the topographical distribution of the haptens on lipid membranes was ...
Keiichiro Hashimoto +4 more
core
Use of novel haptens in the production of antibodies for the detection of tryptamines [PDF]
, 2018 We synthesized haptens derived from tryptamine-based drugs and used them in the production of antibodies against various tryptamines.
Lucie Fojtíková +5 more
core +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
Allergy, EarlyView.DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source