Results 51 to 60 of about 8,472 (222)

Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice. [PDF]

PLoS ONE, 2013
Anti-nicotine vaccines may aid smoking cessation via the induction of anti-nicotine antibodies (Ab) which reduce nicotine entering the brain, and hence the associated reward.
David C Pryde, Lyn H Jones, David P Gervais, David R Stead, David C Blakemore, Matthew D Selby, Alan D Brown, Jotham W Coe, Matthew Badland, David M Beal, Rebecca Glen, Yvonne Wharton, Gavin J Miller, Phil White, Ningli Zhang, Michelle Benoit, Karen Robertson, James R Merson, Heather L Davis, Michael J McCluskie   +19 more
doaj   +1 more source

Copper and Cobalt Ions Released from Metal Oxide Nanoparticles Trigger Skin Sensitization

Frontiers in Pharmacology, 2021
Human skins are exposed to nanomaterials in everyday life from various sources such as nanomaterial-containing cosmetics, air pollutions, and industrial nanomaterials. Nanomaterials comprising metal haptens raises concerns about the skin sensitization to
Sung-Hyun Kim, Jin Hee Lee, Kikyung Jung, Jun-Young Yang, Hyo-Sook Shin, Jeong Pyo Lee, Jayoung Jeong, Jae-Ho Oh, Jong Kwon Lee   +8 more
doaj   +1 more source

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source

Detection of ustilaginoidins in rice samples by immunoassay based on monoclonal antibodies prepared from hemiustilaginoidin-derived haptens

Heliyon, 2023
Ustilaginoidins are a class of bis-naphtho-γ-pyrone mycotoxins to threaten humans, animals and environment. Ustilaginoidins are produced by Villosiclava virens, the rice false smut pathogen.
Weixuan Wang, Xiaoxiang Fu, Yihao Li, Mingpeng Jing, Yonglin Yang, Dan Xu, Daowan Lai, Mingan Wang, Baomin Wang, Ligang Zhou   +9 more
doaj   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Synthesis of Haptens 1, 2, 3, 4, 6 and 7.

, 2013
Synthesis of Haptens 1, 2, 3, 4, 6 and 7.
Heather L. Davis (465261), Phil White (465256), James R. Merson (465260), Lyn H. Jones (465244), Alan D. Brown (465249), Michelle Benoit (465258), David C. Pryde (353590), Yvonne Wharton (465254), Jotham W. Coe (465250), Ningli Zhang (465257), David P. Gervais (465245), David C. Blakemore (465247), Rebecca Glen (465253), Matthew Badland (465251), Gavin J. Miller (465255), David M. Beal (465252), Michael J. McCluskie (465262), David R. Stead (465246), Matthew D. Selby (465248), Karen Robertson (465259)   +19 more
core   +1 more source

Synthesis of skeletally diverse ß-lactam haptens for the in vitro diagnosis of IgE-mediated drug allergy

, 2022
[EN] We present the first synthesis of beta-lactam-derived haptens, leveraging the principles of diversity-oriented synthesis to discover compounds for drug allergy in vitro testing.
Peña-Mendizábal, Edurne, Morais, Sergi, Hernández-Fernández de Rojas, Dolores, Maquieira, Angel, Ibáñez-Echevarría, Ethel, Schreiber, Stuart L., Hua, Bruce K.   +6 more
core   +1 more source

Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview

Medicina, 2022
The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity.
Ana Maria Alexandra Stănescu, Ana-Maria-Antoaneta Cristea, Gabriel Cristian Bejan, Mariana Vieru, Anca Angela Simionescu, Florin-Dan Popescu   +5 more
doaj   +1 more source

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source

Changing Functionality of Surfaces by Directed Self-Assembly Using Oligonucleotides—The Oligo-Tag

BioTechniques, 1999
A method is presented to modify surfaces for biotechnological applications. Oligonucleotides have been coupled covalently to a pre-activated surface. Complementary oligonucleotides hybridize to the surface, which are conjugated with functionalities.
Frank F. Bier, Frank Kleinjung, Eva Ehrentreich-Förster, Frieder W. Scheller   +3 more
doaj   +1 more source