Results 31 to 40 of about 8,480 (219)
Nicotine Haptens 3′-AmNic-rEPA and 6-CMUNic-KLH. [PDF]
Nicotine Haptens 3′-AmNic-rEPA and 6-CMUNic-KLH.
Katherine E. Cornish (491895) +3 more
core +1 more source
Drugs may stimulate the immune system by forming hapten–carrier complexes or via their pharmacological features, namely by noncovalent binding to proteins such as immune receptors.
Werner J. Pichler
doaj +1 more source
Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases Via Haptenation
Haptens are small molecules that only elicit an immune response when bound to proteins. Haptens initially bind to self-proteins and activate innate immune responses by complex mechanisms via inflammatory cytokines and damage-associated molecular patterns
Eri Sakamoto +14 more
doaj +1 more source
Opioid-Based Haptens: Development of Immunotherapy. [PDF]
Over the past decades, extensive preclinical research has been conducted to develop vaccinations to protect against substance use disorder caused by opioids, nicotine, cocaine, and designer drugs. Morphine or fentanyl derivatives are small molecules, and
Hosztafi S +5 more
europepmc +2 more sources
The molecular structures of two haptens for triazophos. [PDF]
The molecular structures of two haptens for triazophos.
Pengfei Du (513926) +11 more
core +1 more source
An expedient synthesis of 5-n-alkylresorcinols and novel 5-n-alkylresorcinol haptens
The first synthesis of bioactive long alkyl chain 5-n-alkylresorcinols, present in whole grain products, by a novel modification of the Wittig reaction is described. All the main long chain 5-n-alkylresorcinols present in rye and wheat, including C23 and
Kirsti Parikka, Kristiina Wähälä
doaj +1 more source
Alternative Hapten Design for Zearalenone Immunoreagent Generation
Appropriate hapten design and synthesis have been identified as critical steps to generate high-performance immunoreagents and to develop sensitive and selective immunoanalytical methods.
Antonio Abad-Fuentes +5 more
doaj +1 more source
Yeast surface display techniques have been increasingly employed as a tool for both the discovery and affinity maturation of antibodies. In this study, we describe the use of yeast surface display for the selection and affinity maturation of antibodies ...
Bhupal Ban +2 more
doaj +1 more source
Synthesis of Haptens 1, 2, 3, 4, 6 and 7. [PDF]
Synthesis of Haptens 1, 2, 3, 4, 6 and 7.
Heather L. Davis (465261) +19 more
core +1 more source
Synthesis of skeletally diverse ß-lactam haptens for the in vitro diagnosis of IgE-mediated drug allergy [PDF]
[EN] We present the first synthesis of beta-lactam-derived haptens, leveraging the principles of diversity-oriented synthesis to discover compounds for drug allergy in vitro testing.
Peña-Mendizábal, Edurne +6 more
core +1 more source

