Results 31 to 40 of about 8,480 (219)

Nicotine Haptens 3′-AmNic-rEPA and 6-CMUNic-KLH. [PDF]

open access: yes, 2013
Nicotine Haptens 3′-AmNic-rEPA and 6-CMUNic-KLH.
Katherine E. Cornish (491895)   +3 more
core   +1 more source

Consequences of drug binding to immune receptors: Immune stimulation following pharmacological interaction with immune receptors (T-cell receptor for antigen or human leukocyte antigen) with altered peptide-human leukocyte antigen or peptide

open access: yesDermatologica Sinica, 2013
Drugs may stimulate the immune system by forming hapten–carrier complexes or via their pharmacological features, namely by noncovalent binding to proteins such as immune receptors.
Werner J. Pichler
doaj   +1 more source

Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases Via Haptenation

open access: yesBiology, 2023
Haptens are small molecules that only elicit an immune response when bound to proteins. Haptens initially bind to self-proteins and activate innate immune responses by complex mechanisms via inflammatory cytokines and damage-associated molecular patterns
Eri Sakamoto   +14 more
doaj   +1 more source

Opioid-Based Haptens: Development of Immunotherapy. [PDF]

open access: yesInt J Mol Sci
Over the past decades, extensive preclinical research has been conducted to develop vaccinations to protect against substance use disorder caused by opioids, nicotine, cocaine, and designer drugs. Morphine or fentanyl derivatives are small molecules, and
Hosztafi S   +5 more
europepmc   +2 more sources

The molecular structures of two haptens for triazophos. [PDF]

open access: yes, 2015
The molecular structures of two haptens for triazophos.
Pengfei Du (513926)   +11 more
core   +1 more source

An expedient synthesis of 5-n-alkylresorcinols and novel 5-n-alkylresorcinol haptens

open access: yesBeilstein Journal of Organic Chemistry, 2009
The first synthesis of bioactive long alkyl chain 5-n-alkylresorcinols, present in whole grain products, by a novel modification of the Wittig reaction is described. All the main long chain 5-n-alkylresorcinols present in rye and wheat, including C23 and
Kirsti Parikka, Kristiina Wähälä
doaj   +1 more source

Alternative Hapten Design for Zearalenone Immunoreagent Generation

open access: yesToxins, 2022
Appropriate hapten design and synthesis have been identified as critical steps to generate high-performance immunoreagents and to develop sensitive and selective immunoanalytical methods.
Antonio Abad-Fuentes   +5 more
doaj   +1 more source

Yeast Surface Display Platform for Rapid Selection of an Antibody Library via Sequential Counter Antigen Flow Cytometry

open access: yesAntibodies, 2022
Yeast surface display techniques have been increasingly employed as a tool for both the discovery and affinity maturation of antibodies. In this study, we describe the use of yeast surface display for the selection and affinity maturation of antibodies ...
Bhupal Ban   +2 more
doaj   +1 more source

Synthesis of Haptens 1, 2, 3, 4, 6 and 7. [PDF]

open access: yes, 2013
Synthesis of Haptens 1, 2, 3, 4, 6 and 7.
Heather L. Davis (465261)   +19 more
core   +1 more source

Synthesis of skeletally diverse ß-lactam haptens for the in vitro diagnosis of IgE-mediated drug allergy [PDF]

open access: yes, 2022
[EN] We present the first synthesis of beta-lactam-derived haptens, leveraging the principles of diversity-oriented synthesis to discover compounds for drug allergy in vitro testing.
Peña-Mendizábal, Edurne   +6 more
core   +1 more source

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