Results 21 to 30 of about 9,284 (223)
Experimental Biology and Medicine, 1926 Abstract In attempting to purify the specific part of the heterogenetic haptene, present in alcoholic extracts of horse kidneys, fractions were obtained which are distinguished from the common lipoids by their solubility in water. The material of one fraction described recently3 is practically insoluble in alcohol, chloroform and ether ...
K Landsteiner, P A Levene
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Dermatologica Sinica, 2013 Drugs may stimulate the immune system by forming hapten–carrier complexes or via their pharmacological features, namely by noncovalent binding to proteins such as immune receptors.
Werner J. Pichler
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Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases Via Haptenation
Biology, 2023 Haptens are small molecules that only elicit an immune response when bound to proteins. Haptens initially bind to self-proteins and activate innate immune responses by complex mechanisms via inflammatory cytokines and damage-associated molecular patterns
Eri Sakamoto +14 more
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Alternative Hapten Design for Zearalenone Immunoreagent Generation
Toxins, 2022 Appropriate hapten design and synthesis have been identified as critical steps to generate high-performance immunoreagents and to develop sensitive and selective immunoanalytical methods.
Antonio Abad-Fuentes +5 more
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Antibodies, 2022 Yeast surface display techniques have been increasingly employed as a tool for both the discovery and affinity maturation of antibodies. In this study, we describe the use of yeast surface display for the selection and affinity maturation of antibodies ...
Bhupal Ban +2 more
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Novel mouse model of colitis characterized by hapten-protein visualization
BioTechniques, 2010 Trinitrobenzene sulfonic acid (TNBS) and oxazolone are used to induce colitis for the investigation of inflammatory reactions in the colon. Although these chemicals are presumed to bind proteins in the colonic mucosa and then induce colitis as haptens ...
Kazuhiro Ishiguro +4 more
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Single-Domain Antibodies As Versatile Affinity Reagents for Analytical and Diagnostic Applications
Frontiers in Immunology, 2017 With just three CDRs in their variable domains, the antigen-binding site of camelid heavy-chain-only antibodies (HcAbs) has a more limited structural diversity than that of conventional antibodies.
Gualberto Gonzalez-Sapienza +2 more
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A New Type of Modified Brassinosteroids for Enzyme-linked Immunosorbent Assay
Natural Product Communications, 2008 New modified brassinosteroids (BS) with a full set of specific functional groups and with an additional one at C-26 have been synthesized and used as haptens for enzyme-linked immunosorbent assay. The haptens were conjugated to bovine serum albumin (BSA)
Vladimir Khripach +9 more
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Dimerization kinetics of the IgE-class antibodies by divalent haptens. II. The interactions between intact IgE and haptens [PDF]
, 1992 Interactions between a monoclonal, DNP-specific IgE molecules (hybridoma A2) and divalent DNP-haptens in solution cause aggregation of the former predominantly into closed rings of two IgE and two divalent haptens (Schweitzer-Stenner, R., A.
Pecht, I. +2 more
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Journal of Lipid Research, 1972 Rabbit antisera to rat lymphosarcoma contain antibodies that are cytolytic for rat erythrocytes in the presence of complement. The reaction can be inhibited completely by pure cytolipin R showing that (a) immune hemolysis can be mediated through lipid ...
Keizo Inoue +2 more
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