Results 21 to 30 of about 8,480 (219)
A Lincomycin-Specific Antibody Was Developed Using Hapten Prediction, and an Immunoassay Was Established to Detect Lincomycin in Pork and Milk [PDF]
FoodsProlonged consumption of animal-derived foods containing high levels of lincomycin (LIN) residues can adversely impact human health. Therefore, it is essential to develop specific antibodies and immunoassay methods for LIN.
Yuhan Shang +5 more
doaj +2 more sources
Chemosensors, 2022 Folic acid (FA) and its other forms known as folates are small molecules vital for humans. The high demand for increasingly sensitive methods of measuring folate concentrations is due to the fact that abnormal levels of FA cause severe health disorders ...
Denis O. Novichikhin +4 more
doaj +1 more source
Immunity, Inflammation and Disease, 2022 Introduction Contact hypersensitivity (CHS), a type of delayed‐type hypersensitivity, is induced by hapten exposure to the skin and mucosa. We previously reported that, in a murine model of CHS, the vaginal mucosa (VM) sensitization showed lower T‐cell ...
Kanako Nakayama +5 more
doaj +1 more source
Construction of an enantiopure bivalent nicotine vaccine using synthetic peptides. [PDF]
PLoS ONE, 2017 Clinical outcomes of anti-nicotine vaccines may be improved through enhancements in serum antibody affinity and concentration. Two strategies were explored to improve vaccine efficacy in outbred mice: the use of enantiopure haptens and formulation of a ...
David F Zeigler +2 more
doaj +1 more source
Role of hydrophobic interaction in hapten-antibody binding [PDF]
, 1977 The precipitation reaction of bovine serum albumin coupled with p-azophenylleucine with homologous antibody was inhibited by several structurally related haptens. The isobutyl group substituent on alpha-carbon atom of the leucine residue contributed more
Oda, Takuzo +5 more
core +1 more source
SYNTHESIS OF 25-HYDROXYVITAMIN D3 CONJUGATE WITH KEYHOLE LIMPET HEMOCYANIN AND OBTAINING OF IMMUNE SERA [PDF]
Biotechnologia Acta, 2015 The study was aimed at obtaining polyclonal antibodies that recognize 25-Hydroxyvitamin D3, for their further specifications and applications in immunochemical test systems of 25-Hydroxyvitamin D3, determination in blood serum.
А. O. Mazanova +5 more
doaj +1 more source
Portrait of an autologous cancer vaccine: Then and now
Human Vaccines & Immunotherapeutics, 2023 Active immunotherapy of cancer with therapeutic vaccines has been the subject of experimental and clinical studies for at least 50 years. Our approach has employed 1) autologous, human cancer cells because of extensive evidence that tumor rejection ...
David Berd
doaj +1 more source
Synthesis of a psilocin hapten and a protein-hapten conjugate
Journal of Pharmacy and Pharmacology, 2002 Abstract Derivatives of psilocin with ω-functionalized alkyl spacers in position 1 of the indole ring were synthesized as haptens for use in a radioimmunoassay. Whereas the psilocin analogues with a 3-aminopropyl and a 4-aminobutyl moiety at the indole nitrogen decomposed during synthesis, the analogous 3-carboxypropyl psilocin ...
Christian, Albers +4 more
openaire +2 more sources
Experimental Biology and Medicine, 1926 Abstract In attempting to purify the specific part of the heterogenetic haptene, present in alcoholic extracts of horse kidneys, fractions were obtained which are distinguished from the common lipoids by their solubility in water. The material of one fraction described recently3 is practically insoluble in alcohol, chloroform and ether ...
K Landsteiner, P A Levene
openaire +1 more source
Contact allergens in moisturizers in preventative emollient therapy – A systematic review
Clinical and Translational Allergy, 2022 Background Results of preventative emollient therapy on atopic dermatitis and food allergy trials are inconsistent. In addition to the ingredients considered beneficial, the moisturizers may contain potentially harmful haptens. This study aimed to assess
Klaudia Ryczaj +3 more
doaj +1 more source