Results 11 to 20 of about 9,284 (223)
Synthesis of haptens and production of antibodies to bisphenol A [PDF]
Frontiers of Agricultural Science and Engineering, 2017 Three immunizing haptens of bisphenol A (BPA), including two new haptens, were used to produce highly sensitive and specific polyclonal antibodies. The spacer arms of haptens for coupling to the protein carrier were located at different positions in BPA,
Xiya ZHANG, Xiaoyun DONG, Sijun ZHAO, Yuebin KE, Kai WEN, Suxia ZHANG, Zhanhui WANG, Jianzhong SHEN
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Alergologia PolskaThe necessity of routine patch testing to topical medications reflects the frequency of contact allergy to these haptens as well as their presence in many popular medicinal products. At present, Polish Baseline Series includes 7 drugs tested individually
Radosław Śpiewak +2 more
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Molecules, 2022 In our continuing effort to develop effective anti-heroin vaccines as potential medications for the treatment of opioid use disorder, herein we present the design and synthesis of the haptens: 1-AmidoMorHap (1), 1-AmidoMorHap epimer (2), 1 Amido ...
Agnieszka Sulima +13 more
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Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine [PDF]
Biomolecules, 2019 Histamine (HA) is an important food contaminant generated during food fermentation or spoilage. However, an immunoassay for direct (derivatization free) determination of HA has rarely been reported due to its small size to induce the desired antibodies ...
Lin Luo +9 more
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Biological Activity of the Carrier as a Factor in Immunogen Design for Haptens
Molecules, 2018 Immunoanalytical methods are frequently employed in the detection of hazardous small molecular weight compounds. However, antibody development for these molecules is a challenge, because they are haptens and cannot induce a humoral immune response in ...
Özlem Ertekin +3 more
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Role of hydrophobic interaction in hapten-antibody binding [PDF]
, 1977 The precipitation reaction of bovine serum albumin coupled with p-azophenylleucine with homologous antibody was inhibited by several structurally related haptens. The isobutyl group substituent on alpha-carbon atom of the leucine residue contributed more
Oda, Takuzo +5 more
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SYNTHESIS OF 25-HYDROXYVITAMIN D3 CONJUGATE WITH KEYHOLE LIMPET HEMOCYANIN AND OBTAINING OF IMMUNE SERA [PDF]
Biotechnologia Acta, 2015 The study was aimed at obtaining polyclonal antibodies that recognize 25-Hydroxyvitamin D3, for their further specifications and applications in immunochemical test systems of 25-Hydroxyvitamin D3, determination in blood serum.
А. O. Mazanova +5 more
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Portrait of an autologous cancer vaccine: Then and now
Human Vaccines & Immunotherapeutics, 2023 Active immunotherapy of cancer with therapeutic vaccines has been the subject of experimental and clinical studies for at least 50 years. Our approach has employed 1) autologous, human cancer cells because of extensive evidence that tumor rejection ...
David Berd
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Synthesis of a psilocin hapten and a protein-hapten conjugate
Journal of Pharmacy and Pharmacology, 2002 Abstract Derivatives of psilocin with ω-functionalized alkyl spacers in position 1 of the indole ring were synthesized as haptens for use in a radioimmunoassay. Whereas the psilocin analogues with a 3-aminopropyl and a 4-aminobutyl moiety at the indole nitrogen decomposed during synthesis, the analogous 3-carboxypropyl psilocin ...
Christian, Albers +4 more
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Contact allergens in moisturizers in preventative emollient therapy – A systematic review
Clinical and Translational Allergy, 2022 Background Results of preventative emollient therapy on atopic dermatitis and food allergy trials are inconsistent. In addition to the ingredients considered beneficial, the moisturizers may contain potentially harmful haptens. This study aimed to assess
Klaudia Ryczaj +3 more
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