Results 21 to 30 of about 11,390 (192)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background The American University of Beirut (AUB)‐HAS2 Cardiovascular Risk Index is a newly derived index for preoperative cardiovascular evaluation. It is based on 6 data elements: history of heart disease; symptoms of angina or dyspnea; age ≥75 years;
Habib A. Dakik +9 more
doaj +1 more source
Archives of Medical Science, 2021 Introduction The prognosis of malignant pleural mesothelioma (MPM) is poor, with a limited survival time. In this study, we aimed to examine expression levels of genes selected from relevant literature and to utilize in silico methods to determine genes ...
Hakan Akgun +6 more
doaj +1 more source
Increased SPHK1 and HAS2 Expressions Correlate to Poor Prognosis in Pancreatic Cancer [PDF]
BioMed Research International, 2021 Objective. SPHK1 and HAS2 have been reported to play important roles in tumorigenesis and development. However, their expression and prognostic value in pancreatic cancer (PC) remain unclear. This study is aimed at investigating the expression of SPHK1 and HAS2 on the prognosis of pancreatic cancer. Materials and Methods.
Mengsi Yu +11 more
openaire +2 more sources
Effect of age and gender on pre-operative cardiovascular risk assessment
Perioperative Medicine, 2022 Background The AUB-HAS2 Cardiovascular Risk Index is a recently published tool for pre-operative cardiovascular evaluation. It is based on six data elements: history of heart disease, symptoms of angina or dyspnea, age ≥ 75 years, hemoglobin 3 based on ...
Omar Chehab +5 more
doaj +1 more source
Hyaluronan and Hyaluronidase, which is better for embryo development? [PDF]
, 2016 Our aim was to examine size-specific effects of Hyaluronan (HA) on preimplantation embryo development. We investigated the effects of Hyalovet (HA, 500–750 kDa; the size produced by HA synthase-3, which is abundant in the oviduct), or HA treated with ...
Ali A. Fouladi-Nashta +59 more
core +2 more sources
Role of noncoding RNA in vascular remodelling [PDF]
, 2016 Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H. +2 more
core +1 more source
PP2B and ERK1/2 regulate hyaluronan synthesis of HT168 and WM35 human melanoma cell lines [PDF]
, 2015 Hyaluronan (HA) is the major glycosaminoglycan component of the extracellular matrix in either normal or malignant tissues and it may affect proliferation, motility and differentiation of various cell types.
Gergely, Pál +8 more
core +4 more sources
Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. [PDF]
, 2013 Pax6 encodes a specific DNA-binding transcription factor that regulates the development of multiple organs, including the eye, brain and pancreas. Previous studies have shown that Pax6 regulates the entire process of ocular lens development.
Beebe, David C. +11 more
core +3 more sources
Cancer Cell International, 2021 Background Non-small cell lung cancers (NSCLC) account for most cases of lung cancer. More effort is needed to research new drug and combination therapies for this disease. An anthraquinone derivative, emodin shows anticancer potency.
Mingzhu Li +5 more
doaj +1 more source
Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. [PDF]
, 2017 Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed.
Amatucci, Aldo +16 more
core +2 more sources