Results 141 to 150 of about 1,470,445 (304)

Hortensia M. Rogers to Mrs. Eliza Kortright Monroe Hay., October 1831 [PDF]

open access: yes
Occupied with baby and sick servants. Treating servants. Are to have a convention in Baltimore to pick presidential candidate. Lanced my baby's gums. Describes quilt she is working on. I could not learn much about my old friend from him.
Rogers, Hortensia Monroe
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Marie Antoinette Virginie de Lafayette Lasteyrie du Saillant to Madame Hay., no date [PDF]

open access: yes
Concerns her father Marquis de ...
Lasteyrie du Saillant, Virginie du Motier de La Fayette, marquise de, 1782-1849
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Madame Jeanne Louise Henriette Campan, St. Germaine France to Eliza Kortright Monroe Hay., 9 October 1803 [PDF]

open access: yes
Takes advantage of departure of General McPherson to answer you and to tell you that I am infinitely touched by your kind remembrance. I can not console myself for your departure and that of your dear Parent.
Campan, Mme (Jeanne-Louise-Henriette), 1752-1822
core  

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