Results 151 to 160 of about 1,470,445 (304)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Changes in Producers’ Perceptions of Within-field Yield Variability Following Adoption of Cotton Yield Monitors [PDF]

open access: yes
Precision Farming, Risk, Yield Monitor, Yield Variability, Yield Perceptions, Spatial Yield Distributions, Within Field Variability, Farm Management, Production Economics, Risk and Uncertainty, Q12, Q16,
Roberts, Roland K.   +5 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

(H. M. Rogers) Hortensia to Mrs. Eliza Kortright Monroe Hay., 27 June 1831 [PDF]

open access: yes
Can't come. Child continuously sick. Will come if she thinks grandfather (James Monroe) would even know her - Sam's letter precludes all hope.
Rogers, Hortensia Monroe
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Hortensia Monroe Rogers to Mrs. Eliza Kortright Monroe Hay., October 15, no year [PDF]

open access: yes
Put off writing. Expecting to see Cousin Samuel L. Governeur. Worried about health of child. Thinks Papa will like his room. Ice house had caved in.
Rogers, Hortensia Monroe
core  

Breeding of new variety of Medicago sativa L. cv. Longjing No.1

open access: yesSiliao yanjiu
The experiment aimed to address the scarcity of high-quality alfalfa germplasm resources in cold regions, with cold resistance and high yield as the breeding objectives. Since 2002, nine domestic and foreign alfalfa varieties have been selected through a
WANG Jian-li   +7 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Hortensia M. Rogers to Mrs. Eliza Kortright Monroe Hay., 4 January 1831 [PDF]

open access: yes
Mr. Rogers looks badly. All the servants have the measles. Sorry to read accounts of 1 of January dinners. He James Monroe is very old and recent misfortune demands seculsion not solitude.
Rogers, Hortensia Monroe
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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