Results 61 to 70 of about 42,544 (264)

Study of hepatic histomorphology in HBeAg+ and HBeAg− patients with CHB: Experience from Bangladesh

Journal of Acute Disease, 2013
AbstractObjectiveTo compare Knodell and HAI scores in patients with wild type and pre-core/core promoter mutant CHB to see if there is any difference in severity of liver injury between these two types of HBV.MethodsWe did percutaneous liver biopsies of 155 CHB patients.
Ayub Al Mamun, Mamun-Al-Mahtab, S.M. Fazle Akbar, Kutub Uddin Mollick, Arun Jyoti Tarafdar, Faiz Ahmad Khondokar, Ahmed Lutful Mubin, Md. Helal Uddin, Salimur Rahman   +8 more
openaire   +2 more sources

HBV-DNA level at 6 months of entecavir treatment predicts HBeAg loss in HBeAg-positive chronic hepatitis B patients [PDF]

, 2015
To evaluate whether on-treatment HBV-DNA level could predict the treatment response to entecavir in hepatitis B e antigen (HBe)-positive chronic hepatitis B (CHB) patients.
Chia-Chi Wang, Kuo-Chih Tseng, Chih-Lin Lin, Jia-Horng Kao, Tsung-Cheng Hsieh, Tung-Hung Su, Cheng-Yuan Peng, Hans Hsienhong Lin, Tsai-Yuan Hsieh, Tai-Chung Tseng   +9 more
core   +3 more sources

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source

Whole genome deep sequencing analysis of viral quasispecies diversity and evolution in HBeAg seroconverters

JHEP Reports, 2021
Summary: Background & Aims: We aimed to investigate how viral quasispecies of the HBV whole genome evolves and diversifies in response to HBeAg seroconversion and viral control utilising next-generation sequencing (NGS).
Su-Ru Lin, Ta-Yu Yang, Cheng-Yuan Peng, You-Yu Lin, Chia-Yen Dai, Hurng-Yi Wang, Tung-Hung Su, Tai-Chung Tseng, I-Jung Liu, Huei-Ru Cheng, Yueh-Chi Shen, Fang-Yi Wu, Chun-Jen Liu, Ding-Shinn Chen, Pei-Jer Chen, Hung-Chih Yang, Jia-Horng Kao   +16 more
doaj   +1 more source

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Immunomodulatory Function of HBeAg Related to Short-Sighted Evolution, Transmissibility, and Clinical Manifestation of Hepatitis B Virus

Frontiers in Microbiology, 2018
Hepatitis B virus (HBV) infection, a global public health problem can be asymptomatic, acute or chronic and can lead to serious consequences of infection, including cirrhosis, and hepatocellular carcinoma.
A. Kramvis, E. Kostaki, A. Hatzakis, D. Paraskevis   +3 more
semanticscholar   +1 more source

"IL28B polymorphism in chronic HBV infection: the CC allele does not correlate with the phase of the infection nor with HBsAg clearance in IFN treated patients". [PDF]

, 2012
IL28B polymorphism (IL28Bp) is associated with spontaneous and treatment induced HCV clearance, whereas its role in HBV infection is still debated. We analysed the correlation between IL28Bp and phase and outcome of HBV infection and HBsAg clearance in ...
CHERUBINI, BEATRICE
core  

Predictors for early HBeAg loss during lamivudine therapy in HBeAg-positive chronic hepatitis B patients with acute exacerbation [PDF]

, 2010
Purpose To examine the rate of early HBeAg loss and predictors of HBeAg loss in HBeAg-positive chronic hepatitis B (CHB) patients with acute exacerbation (AE) treated with lamivudine.
Lai, H.C., Long-Bin Jeng, Chuang, P.H., Chih-Bin Chen, Hong-Dar Isaac Wu, Su, W.P., Jeng, L.B., Wen-Pang Su, Chen, C.B., Po-Heng Chuang, Cheng-Yuan Peng, Hsueh-Chou Lai, Wu, H.D.I., Peng, C.Y.   +13 more
core   +1 more source

Comparison of evolutionary patterns of different HBeAg status in HBV genotype B and C

Open Life Sciences, 2015
The aim of this work was to investigate the different evolutionary patterns between HBeAg(+) and HBeAg(-) status of genotype B and genotype C of Hepatitis B virus (HBV).
Cai Ying, Wu Xiaomei, Shi Yunhui, Liu Wei   +3 more
doaj   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source