Results 81 to 90 of about 49,566 (218)

Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi

BMC Infectious Diseases, 2021
Background The World Health Organization (WHO) has targeted a reduction in viral hepatitis-related mortality by 65% and incidence by 90% by 2030, necessitating enhanced hepatitis B treatment and prevention programmes in low- and middle-income countries ...
Alexander J. Stockdale, Niza M. Silungwe, Isaac Thom Shawa, Benno Kreuels, Melita A. Gordon, Anna Maria Geretti   +5 more
doaj   +1 more source

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham, Leja Hamza, Azeb Kebede, Daniel Rebuma Bekele, Zekarias Amdemariam   +4 more
wiley   +1 more source

Prevalence and clinical significance of HBeAg-positive chronic hepatitis B patients with and without anti-HBe antibody

Virulence
The clinical significance of the coexistence of hepatitis B e antigen (HBeAg) and antibodies against HBeAg (anti-HBe) in patients with chronic hepatitis B (CHB) remains unclear.
Ruifei Xue, Jian Wang, Jie Zhan, Zhiyi Zhang, Suling Jiang, Jiacheng Liu, Li Wang, Xiaomin Yan, Shengxia Yin, Xin Tong, Weimao Ding, Jie Li, Yuxin Chen, Rui Huang, Chao Wu   +14 more
doaj   +1 more source

Association Between Polymorphisms rs11003125 and rs7096206 of the MBL2 Gene and the Stages of Hepatitis B Progression in Burkina Faso: A Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Objectives Hepatitis B virus (HBV) infection remains a major global health burden, with disease progression influenced by host genetic and immune factors, including variants in the mannose‐binding lectin 2 (MBL2) gene. This study aimed to evaluate the association between MBL2 polymorphisms and clinical outcomes of HBV infection ...
Minane Nafissa Triande, Lassina Traore, Sidnooma Véronique Zongo, Teega‐Wendé Clarisse Ouedraogo, Mousso Savadogo, Sanata Nadine Kiemde, Tegwindé Rébéca Compaore, Augustin Tozoula Bambara, Roger Arsène Sombie, Patoinewendé Denise Ilboudo, Albert Théophane Yonli, Bolni Marius Nagalo, Florencia Wendkuuni Djigma, Jacques Simpore   +13 more
wiley   +1 more source

Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution.

PLoS ONE, 2014
AimTo evaluate HBV quasispecies (QA) complexity in the preCore/Core regions in relation to HBeAg status, and explore QA changes under natural evolution and nucleoside analogue (NUC) treatment.MethodsUltra-deep pyrosequencing of HBV preCore/Core regions ...
Maria Homs, Andrea Caballero, Josep Gregori, David Tabernero, Josep Quer, Leonardo Nieto, Rafael Esteban, Maria Buti, Francisco Rodriguez-Frias   +8 more
doaj   +1 more source

Tenofovir Alafenamide in the Treatment of Chronic Hepatitis B Virus Infection in the High‐Replicative Low‐Inflammatory Phase: A 48‐Week Randomized Controlled Trial

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Antiviral treatment for chronic HBV infection in the “high‐replicative low‐inflammatory” phase has not been widely recommended. This study aimed to evaluate the safety and efficacy of antiviral therapy in this patient population and analyze peripheral immunological characteristics in relation to treatment response.
Qiumin Luo, Ruixuan Xu, Yeqiong Zhang, Wenxiong Xu, Xiangyong Li, Jing Lai, Jianguo Li, Xingrong Zheng, Hong Deng, Lubiao Chen, Xiang Zhu, Chan Xie, Liang Peng   +12 more
wiley   +1 more source

Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]

, 2013
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F., Alavian, S.M., Ataei, B., Azad, T.M., Daram, M., Fazeli, Z., Ghamari, S., Goodarzi, Z., Jazayeri, S.M., Judaki, M.A., Kalantari, E., Karimzadeh, H., Keyvani, H., Khedive, A., Mahabadi, M., Mahmoodi, M., Malekzadeh, R., Mansour-Ghanaei, F., Montazeri, G., Moradi, A., Nejatizadeh, A., Norouzi, M., Pourhosseingholi, M.A., Rafatpanah, H., Ramezani, F., Saberfar, E., Saberfiroozi, M., Samimirad, K., Sanei-Moghaddam, I., Sarizadeh, G., Sayad, B., Somi, M.H., Yaran, M., Ziee, M.   +33 more
core   +1 more source

Chronic HBV infection in pregnant immigrants: a multicenter study of the Italian Society of Infectious and Tropical Diseases [PDF]

, 2016
The aims of the study were to estimate the clinical impact of HBV infection in pregnant immigrants and their family members and to identify a useful approach to managing the healthcare of HBsAg-positive immigrants.
Armignacco, Orlando, Bartolozzi, Dario, Cacopardo, Bruno, Castelli, Francesco, Coppola, Nicola, Sagnelli, Caterina, Sagnelli, Evangelista, Scotto, Gaetano, Stroffolini, Tommaso, Taliani, Gloria   +9 more
core  

The association between maternal hepatitis B e antigen status, as a proxy for perinatal transmission, and the risk of hepatitis B e antigenaemia in Gambian children. [PDF]

, 2014
BACKGROUND: Early age at infection with hepatitis B virus (HBV) increases the risk of chronic HBV infection. In addition early age at infection may further increase the risk of persistent viral replication beyond its effect on chronicity.
Bottomley, Christian, Mendy, Maimuna, Njie, Ramou, Shimakawa, Yusuke   +3 more
core   +4 more sources

Cost‐Effectiveness of Interventions to Improve Retention in Care for Chronic Hepatitis B in the United States

Journal of Viral Hepatitis, Volume 33, Issue 5, May 2026.
ABSTRACT Monitoring and retention in care remain suboptimal for patients diagnosed with chronic hepatitis B (CHB) infection with only a minority receiving consistent follow‐up. This study evaluates the cost‐effectiveness of interventions aimed at improving long‐term monitoring and retention in care among diagnosed CHB. A Markov model simulated outcomes
Irene Starinieri, Amit Chitnis, Robert J. Wong, Emily Yette, Hang Pham, Amy S. Tang, Samuel So, Mehlika Toy   +7 more
wiley   +1 more source