Results 101 to 110 of about 1,553,868 (271)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Few prediction models have been specifically designed to evaluate the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B and cirrhosis. This study aimed to develop a machine learning‐based prediction model to assess the risk of developing HCC in patients with hepatitis B virus (HBV)‐related cirrhosis undergoing nucleos(
Pao‐Yuan Huang +4 more
wiley +1 more source
Therapeutics and Clinical Risk Management, 2015 Wenbo Shao, Fengjuan Zhang, Ning Cong, Jinpeng Li, Jinlong SongDepartment of Surgical Oncology (Interventional Therapy), Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, People’s Republic of ChinaObjective ...
Shao W, Zhang F, Cong N, Li J, Song J
doaj
HBV DNA Integration: Molecular Mechanisms and Clinical Implications
Viruses, 2017 Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and mortality. One peculiar observation in cells infected with HBV (or with closely‑related animal hepadnaviruses) is the presence of viral DNA integration in the host cell genome, despite this form being a replicative dead-end for the virus.
Thomas Tu +3 more
openaire +6 more sources
Risk stratification for hepatitis B virus related hepatocellular carcinoma
, 2014 Hepatitis B virus (HBV) infection is the major cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC) worldwide, especially in the Asia-Pacific region.
Lin, Chih-Lin;Kao, Jia-Horng, 高嘉宏
core
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Serum‐based fibrosis scores are widely used for noninvasive risk stratification in chronic liver disease; however, direct comparisons across liver disease etiologies remain limited, particularly in Asian populations with a high prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection.
Sheng‐Feng Lin, Chun‐Chao Chang
wiley +1 more source
HBV DNA Quantitation Using Real-time PCR
Annals of Laboratory Medicine, 2006 Accurate measurement of the concentration of hepatitis B virus (HBV) DNA in clinical samples is important for the appropriate treatment of patients and evaluation of their therapeutic responses. In addition, the concentration of HBV DNA in the serum of patients with chronic HBV infection has a very broad range.
Jeong, Heo +7 more
openaire +2 more sources
Hepatitis B virus in silvery gibbons (Hylobates moloch) [PDF]
, 2004 This research investigated a number of issues regarding hepatitis B virus (HBV) in the silvery gibbon (Hylobates moloch). Due to the relatively recent discovery of the virus in nonhuman primate populations, specific knowledge of the biological behaviour ...
Payne, Karen Louise
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Organoid Coculture Models for Cancer Research and Immunotherapy
Med Research, EarlyView.This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang +9 more
wiley +1 more source
Quantification of the genome equivalent of HBV virion DNA in concentrated HBV particles.
, 2015 (A) HBV virions and naked capsids in the indicated volume of virus stock were separated by native agarose gel electrophoresis, and viral DNA was detected by hybridization.
Dawei Cai (433179) +5 more
core +1 more source
Advances in Viral Markers for Predicting Functional Cure of Chronic Hepatitis B
Portal Hypertension &Cirrhosis, EarlyView.Functional cure, defined as sustained hepatitis B surface antigen (HBsAg) loss, is achieved by only a minority of patients with chronic hepatitis B (CHB); early identification of likely responders may improve cure rates and reduce costs. However, responses to antiviral therapy vary considerably, necessitating reliable hepatitis B virus (HBV) viral ...
Xinrong Lu +3 more
wiley +1 more source