Results 81 to 90 of about 1,553,868 (271)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment [PDF]

open access: yes, 2003
Lamivudine treatment in chronic hepatitis B leads to the reconstitution of virus-specific T cells in the circulation, but it is not clear whether this is the preferential result of T cell efflux from the liver or lymph nodes.
Gotto, J   +8 more
core  

The risky body mass index ranges for significant hepatitis B viral load: A campus-based study

open access: yes, 2014
Significant hepatitis B viral load (>= 10,000 copies/mL) was established to increase risk of advanced liver diseases. The aim of this study was to explore the metabolic risk factors for significant hepatitis B viral load.
Chiang, Chien-Hsieh;Lai, Jin-Shin;Sheu, Jin-Chuan;Yen, Lee-Lan;Liu, Chun-Jen;Huang, Kuo-Chin   +1 more
core   +1 more source

Decoding sequence recognition code of nucleic acid‐binding proteins of human‐infecting DNA viruses

open access: yesiMeta, EarlyView.
Human‐infecting DNA viruses remain major health threats, yet the DNA‐recognition mechanisms of their nucleic acid‐binding proteins (NBPs) are poorly understood. Here, we systematically profiled 103 viral NBPs from human‐infecting DNA viruses, with three NBPs from non‐human‐infecting DNA viruses as controls, using high‐throughput screening.
Meifang Tang   +10 more
wiley   +1 more source

HBV DNA replication in Hep-Y1 cells after HBV infection.

open access: yes, 2013
(A) Southern blot kinetic analysis of PCR products after infection of Hep-Y1 cells with control normal HBV-negative serum and HBV-containing serum. P1 and P2, 1 pg and 50 pg of PCR products derived from HBV DNA were loaded. (B) Quantification of HBV DNA.
Chih-Lang Lin (586444)   +5 more
core   +1 more source

Frontiers in transition‐metal single‐atom electrocatalysts: Design tactics, mechanistic regulation, and electrochemical sensing technologies

open access: yesInfoMat, EarlyView.
This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao   +8 more
wiley   +1 more source

Insights into Hepatitis B Virus DNA Integration-55 Years after Virus Discovery

open access: yesThe Innovation, 2020
Hepatitis B virus (HBV), which was discovered in 1965, is a threat to global public health. HBV infects human hepatocytes and leads to acute and chronic liver diseases, and there is no cure.
Kaitao Zhao, Andrew Liu, Yuchen Xia
doaj   +1 more source

Quantitation of HBV covalently closed circular DNA (HBV CCC DNA) in HCC patients

open access: yes, 2004
Objective: Hepatitis B virus (HBV) is a major causative agent of hepatocellular carcinoma (HCC). We aimed to use the Invader assay to measure the intrahepatic total HBV DNA and covalently closed circular (ccc) DNA in the tumorous and non-tumorous ...
Poon, RTP   +4 more
core   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Correlation between intrahepatic HBV cccDNA and HBV total DNA or serum HBV DNA.

open access: yes, 2016
A significant correlation was observed between total intrahepatic cccDNA levels and HBV DNA (panel A), but not for serum HBV DNA level (panel B) among 35 HCC patients with detectable cccDNA in paired samples.
Yanmeng Chen (2839214)   +7 more
core   +1 more source

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