Results 111 to 120 of about 1,553,868 (271)

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

孕妇血、脐血、乳汁的乙型肝炎病毒DNA水平及其相关性

Zhongshan Daxue xuebao. Yixue kexue ban, 2000
【目的】探讨乙型肝炎病毒(HBV)母婴垂直传播的规律, 为预防和阻断HBV 的母婴传播提供依据。【方法】对68 例HBsAg 阳性孕产妇以荧光定量PCR方法检测其静脉血、脐血、乳汁HBV DNA 含量并分析其相关性。【结果】孕妇血与脐血 HBV DNA 的含量相关系数为0.3446(P =0.008), 孕妇血与乳汁HBV DNA 的含量的相关系数为0.1449(P =0.261)。【结论】 孕妇血HBV DNA 水平与脐血HBV DNA 水平呈正相关, 降低孕妇血HBV DNA 水平 ...
李小毛, 刘穗玲, 李　霞, 黄怀筠, 卢建溪, 高志良   +5 more
doaj  

HBV RNA at 6 months after nucleos(t)ide analogues treatment can predict antiviral efficacy in chronic hepatitis B patients

BMC Gastroenterology
Background This multicenter study evaluated serum HBV RNA as a prognostic biomarker for nucleos(t)ide analogue (NA) therapy in chronic hepatitis B (CHB), focusing on correlations with HBV DNA/HBsAg and predictive value for virological response (VR) and ...
Yandi Xie, Xiaojing Zhang, Xiaozhou Yang, Sujun Zheng, Shuyun Zhang, Xiaoying Zhang, Haiyan Kang, Xuefei Duan, Wenpin Cai, Peng Yin, Xinghuan Ma, Juan liu, Fengmin Lu, Lizhong Dai, Bo Feng   +14 more
doaj   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Carbon dots in electrochemiluminescence: Mechanisms, interface engineering, and bioanalytical applications

Responsive Materials, EarlyView.
Carbon dots are emerging as versatile electrochemiluminescent nanomaterials whose structure, surface states, and interfacial design jointly determine ECL pathways and performance. This review highlights how mechanistic understanding and materials engineering enable programmable CD‐ECL systems for bioanalysis, imaging, and future intelligent analytical ...
Yuhan Zhao, Zixuan Chen, Jun‐Jie Zhu
wiley   +1 more source

HBV-DNA in hemodialysis patients infected by HCV.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2009
End-stage renal disease patients on chronic hemodialysis (HD) patients are at risk for both hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, and they may coexist. To determine the prevalence and clinical impact of HBV and HCV infection, we studied poly chain reaction (PCR) and reverse transcription (RT)-PCR on the blood samples of 90 HD ...
Arababadi Mohammad, Hassanshahi Gholamhossein, Yousefi Hassan   +2 more
openaire   +2 more sources

Efficacy Analysis of TACE Combined with Lenvatinib and PD-1 Inhibitors in the Treatment of Hepatitis B Virus-Related Unresectable Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Jin Yu,1 Yuan Zhu,1 Shiyi Zhao,1 Xiaogang Li2 1School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, People’s Republic of China; 2Department of Biliary and Pancreatic Surgery, Xiangyang Central Hospital, Affiliated Hospital of ...
Yu J, Zhu Y, Zhao S, Li X
doaj  

The presence of HBV DNA in glomeruli of HBV-PIGN: Glomeruli were isolated from patients with HBV-PIGN and non-HBV associated PIGN.

, 2016
HBV-DNA in glomeruli were detected by PCR. β-actin was used as a control to verify genomic DNA presence. PCR products with correct size were analyzed by agarose gels together with molecular markers.
Weihua Peng (2938587), Liping Wang (561851), Guoqing Yu (2938584), Feng Zheng (91182), Yong Zhang (5893), Junxia Li (136291), Jian Chen (15340)   +6 more
core   +1 more source

Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy

Allergy, EarlyView.
We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov, Maria G. Byazrova, Evgenii V. Smolnikov, Vladislav N. Turenko, Valeriy V. Smirnov, Igor P. Shilovskii, Nadezhda N. Shershakova, Ekaterina N. Medunitsyna, Olga G. Elisyutina, Mikhail V. Pashenkov, George B. Pasikhov, Vladimir V. Murugin, Veronika A. Parshina, Darya K. Bolyakina, Anastasia S. Primak, Mariya A. Lapyko, Inna V. Danilycheva, Rosalia V. Schubelko, Anastasia A. Tsyvkina, Nataliia V. Shartanova, Daria O. Timoshenko, Irina I. Isakova, Tatiana V. Latysheva, Andrey E. Shulzhenko, Elena A. Latysheva, Oksana M. Kurbacheva, Elena S. Fedenko, Oksana A. Markova, Ilya A. Korotkevich, Violetta V. Yan, Natalia A. Gavrilova, Mariia V. Tikhomirova, Ivan V. Shevchenko, Alena A. Agafonova, Gregory N. Poroshin, Dmitry A. Kudlay, Alexander V. Filatov, Evgeniya V. Nazarova, Daria S. Kruchko, Dmitriy V. Goryachev, Vadim A. Merkulov, Nataliya I. Ilina, Rudolf Valenta, Veronica I. Skvortsova   +43 more
wiley   +1 more source

Clinical superiority of HBV RNA testing in patients with chronic hepatitis B

Frontiers in Immunology
PurposeThis study aimed to thoroughly investigate the detection levels of serum Hepatitis B Virus RNA (HBV RNA) and its clinical significance in Chronic Hepatitis B (CHB) patients before and after treatment.MethodsSerum samples were collected from 487 ...
Jing Zhou, Jing Zhou, Xiaoyan Li, Yulin Yang, Xiaomin Wang, Wenhua Xu   +5 more
doaj   +1 more source