Results 111 to 120 of about 1,221,411 (264)

Knockdown of damage-specific DNA binding protein 1 (DDB1) enhances the HBx-siRNA-mediated inhibition of HBV replication

, 2008
Recent studies have demonstrated that the effect of inhibition of HBV replication can be achieved by RNA interference (RNAi) at both the cellular and organismal levels. However, HBV replication cannot be completely inhibited by this method. To completely
Tang, Kai-Fu, Ren, Hong, Huang, Ai-Long, Zhou, Xi-Yuan, Liu, Qi, Wang, Yan, Zeng, Weiqun, Xie, Jing, K. F. Tang, H. Ren, Zuo, Guo-qing, Chen, Min, Xiang, Rong   +12 more
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The association of HBV core promoter double mutations (A1762T and G1764A) with viral load differs between HBeAg positive and anti-HBe positive individuals: A longitudinal analysis

, 2009
Background/Aims: Although there have been a few reports regarding the effect of basal core promoter (BCP) double mutations (A1762T and G1764A) on hepatitis B viral loads, the association remains uncertain.
Fang, Kong-Xiong, Yang, Jin-Ye, Harrison, Tim J., Wang, Xue-Yan, Wei, SC, Harrison, TJ, Wang, XY, Fang, KX, Chen, QY, Fang, ZL, Dong, Bai-Qing, Wei, Shao-Chao, Chen, Qin-Yan, Sabin, Caroline A, Yang, JY, Sabin, CA, Dong, BQ, Fang, Zhong-Liao   +17 more
core   +1 more source

HBV genotypes and response to tenofovir disoproxil fumarate in HIV/HBV-coinfected persons [PDF]

, 2015
BACKGROUND Hepatitis B virus (HBV) genotypes can influence treatment outcome in HBV-monoinfected and human immunodeficiency virus (HIV)/HBV-coinfected patients.
Rickenbach, Martin, Anna-Paola Caminada, Battegay, Manuel, Calmy, A., Martinetti, Gladys, Enos Bernasconi, Martin Rickenbach, Wandeler, Gilles, Cavassini, M., Wandeler, G., Pietro Vernazza, Battegay, M., Vernazza, P., Calmy, Alexandra, Gladys Martinetti, Bernasconi, Enos, Gilles Wandeler, Weber, R., Bruno Ledergeber, Swiss HIV Cohort Study, Rickenbach, M., Rainer Weber, Alexandra Calmy, Ledergeber, B., Bihl, Florian, Martinetti, G., Caminada, A.P., Manuel Battegay, Caminada, Anna-Paola, Florian Bihl, null null, Vernazza, Pietro, Weber, Rainer, Ledergeber, Bruno, Cavassini, Matthias, Matthias Cavassini, Bihl, F., Bernasconi, E.   +37 more
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Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

孕妇血、脐血、乳汁的乙型肝炎病毒DNA水平及其相关性

Zhongshan Daxue xuebao. Yixue kexue ban, 2000
【目的】探讨乙型肝炎病毒(HBV)母婴垂直传播的规律, 为预防和阻断HBV 的母婴传播提供依据。【方法】对68 例HBsAg 阳性孕产妇以荧光定量PCR方法检测其静脉血、脐血、乳汁HBV DNA 含量并分析其相关性。【结果】孕妇血与脐血 HBV DNA 的含量相关系数为0.3446(P =0.008), 孕妇血与乳汁HBV DNA 的含量的相关系数为0.1449(P =0.261)。【结论】 孕妇血HBV DNA 水平与脐血HBV DNA 水平呈正相关, 降低孕妇血HBV DNA 水平 ...
李小毛, 刘穗玲, 李　霞, 黄怀筠, 卢建溪, 高志良   +5 more
doaj  

MiR‐375 in CAFs‐Derived EVs Promotes HCC Progression via Regulating RASA1 and May Potentially Serve as a Biomarker for HCC

Cancer Science, EarlyView.
CAFs could transfer EVs miR‐375 into endothelial cells with a low level of RASA1 and further promote EC angiogenesis. Plasma EVs miR‐375 have the potential values as a novel diagnostic and prognostic biomarker for HCC. ABSTRACT Cancer‐associated fibroblasts (CAFs) in the tumor microenvironment play an important role in cancer initiation and progression
Wei Qin, Li Wang, Beiyuan Hu, Cuicui Xiao, XiaoYing Wu, Huan Tian, Songlin Peng   +6 more
wiley   +1 more source

The presence of HBV DNA in glomeruli of HBV-PIGN: Glomeruli were isolated from patients with HBV-PIGN and non-HBV associated PIGN.

, 2016
HBV-DNA in glomeruli were detected by PCR. β-actin was used as a control to verify genomic DNA presence. PCR products with correct size were analyzed by agarose gels together with molecular markers.
Weihua Peng (2938587), Liping Wang (561851), Guoqing Yu (2938584), Feng Zheng (91182), Yong Zhang (5893), Junxia Li (136291), Jian Chen (15340)   +6 more
core   +1 more source

Clinical superiority of HBV RNA testing in patients with chronic hepatitis B

Frontiers in Immunology
PurposeThis study aimed to thoroughly investigate the detection levels of serum Hepatitis B Virus RNA (HBV RNA) and its clinical significance in Chronic Hepatitis B (CHB) patients before and after treatment.MethodsSerum samples were collected from 487 ...
Jing Zhou, Jing Zhou, Xiaoyan Li, Yulin Yang, Xiaomin Wang, Wenhua Xu   +5 more
doaj   +1 more source

HBV-DNA in hemodialysis patients infected by HCV.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2009
End-stage renal disease patients on chronic hemodialysis (HD) patients are at risk for both hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, and they may coexist. To determine the prevalence and clinical impact of HBV and HCV infection, we studied poly chain reaction (PCR) and reverse transcription (RT)-PCR on the blood samples of 90 HD ...
Arababadi Mohammad, Hassanshahi Gholamhossein, Yousefi Hassan   +2 more
openaire   +2 more sources

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment

, 2003
Lamivudine treatment in chronic hepatitis B leads to the reconstitution of virus-specific T cells in the circulation, but it is not clear whether this is the preferential result of T cell efflux from the liver or lymph nodes.
Gotto, J, Williams, R, Webster, GJM, Dusheiko, GM, Bertoletti, A, Malacarne, F, Reignat, S, Behboudi, S, Burroughs, AK   +8 more
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