Results 81 to 90 of about 73,125 (286)

Natural history of decompensated cirrhosis with serum hepatitis B DNA < 2000 IU/mL: a retrospective study

open access: yesBMC Gastroenterology, 2022
Background and aims Patients with low HBV DNA levels (
Xu Huang   +5 more
doaj   +1 more source

HBV DNA Integration: Molecular Mechanisms and Clinical Implications

open access: yesViruses, 2017
Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and mortality. One peculiar observation in cells infected with HBV (or with closely‑related animal hepadnaviruses) is the presence of viral DNA integration in the host cell genome, despite this form being a replicative dead-end for the virus.
Thomas Tu   +3 more
openaire   +4 more sources

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

open access: yesAdvanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen   +15 more
wiley   +1 more source

Insights into Hepatitis B Virus DNA Integration-55 Years after Virus Discovery

open access: yesThe Innovation, 2020
Hepatitis B virus (HBV), which was discovered in 1965, is a threat to global public health. HBV infects human hepatocytes and leads to acute and chronic liver diseases, and there is no cure.
Kaitao Zhao, Andrew Liu, Yuchen Xia
doaj   +1 more source

Real-time PCR quantitation of hepatitis B virus DNA using automated sample preparation and murine cytomegalovirus internal control [PDF]

open access: yes, 2005
Quantitation of circulating hepatitis B virus (HBV) DNA is important for monitoring disease progression and for assessing the response to antiviral therapy. Several commercial and 'in house' assays for HBV DNA quantitation have been described but many of
Ayliffe, U   +4 more
core   +1 more source

Association Between Liver Function Grade and Post‐Hepatectomy Liver Failure in Patients With Hepatocellular Carcinoma: A Latent Class Analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We retrospectively analyzed clinical data from patients who underwent hepatectomy for hepatocellular carcinoma (HCC) using LCA‐based grading system. These findings provide a new risk stratification framework for the design of precision surgery to treat patients with HCC.
Ling Liu   +5 more
wiley   +1 more source

Mutations of Glucocorticoid Responsive Element of HBV DNA.

open access: yesThe Kurume Medical Journal, 1998
The mutation of glucocorticoid responsive element (GRE) of HBV DNA obtained from a patient with chronic hepatitis B was evaluated. This patient showed fatal course by glucocorticoid administration. The HBV DNA from this patient (GRE-M) and two patients with HBeAg positive chronic hepatitis B (GRE-W1,2) whose HBV DNA have few mutations, were examined ...
H, Suzuki   +6 more
openaire   +3 more sources

A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani   +5 more
wiley   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Kinetics of hepatitis B virus replication in anti-HBc positive/HBsAg-negative people with HIV switching to tenofovir sparing therapy

open access: yesInternational Journal of Infectious Diseases
Objectives: To unravel the still unexplored HBV-replicative kinetics in anti-HBc-positive/HBsAg-negative people-with-HIV (PWH) suspending tenofovir disoproxil-fumarate/tenofovir-alafenamide (TDF/TAF).
Romina Salpini   +16 more
doaj   +1 more source

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