Results 121 to 130 of about 3,362,872 (199)

C/EBPα enhances HBx-induced SOCS3 expression.

, 2013
(A) Schematic representation of the transcriptional response elements on the murine SOCS3 promoter, showing a distal SRE (−95 to −87), a proximal SRE (−71 to −64), an AP1 element (−105 to −99), a FoxO motif (−103 to 95), a GC-rich region (−58 to −52 ...
JaeHun Cheong (366273), KyeongJin Kim (366271), Kook Hwan Kim (366272)   +2 more
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Differential early gene expression in HBV X protein (HBx)-mediated hepatocarcinogenesis. [PDF]

, 2002
by Ray, Kit Ng.Thesis (M.Phil.)--Chinese University of Hong Kong, 2002.Includes bibliographical references (leaves 112-121).Abstracts in English and Chinese.Abstract --- p.iAcknowledgments --- p.ivAbbreviations --- p.xList of Figures --- p.xiiList of

core  

Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA

Cell Death and Disease
Metabolic dysfunction-associated steatohepatitis (MASH) is one of the fastest-growing chronic liver diseases and is characterized by excessive steatosis, inflammation, and progressive liver injury.
Ze-Bang Du, Tun Han, Yu-Xin Cai, Yu-Shi Shen, Jia-Shen Wu, Xiong Li, Hang-Tian Zhong, Bai-Heng Wu, Lei Zhang, Liang-Yu Wen, Xiao-Ming Luo, Zhong-Ning Lin, Yu-Chun Lin   +12 more
doaj   +1 more source

The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors

, 1995
The HBx protein of hepatitis B virus (HBV) is a transcriptional activator that is required for infection and may play an important role in HBV-associated hepatocarcinogenesis.
Lucito, R., Schneider, R. J., Klein, N., Doria, M.   +3 more
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Hepatitis B virus X protein (HBx)-mediated immune modulation and prognostic model development in hepatocellular carcinoma

Hepatitis B virus (HBV) X protein (HBx) is critical in hepatocellular carcinoma (HCC) development, but its influence on tumor immunity and the tumor microenvironment (TME) remains unclear.
Lin, Yiqi, Zhong, Jianhua, Bi, Changlong, Kong, Xinyi, Zhai, Aixia, Li, Yuetong, Qiao, Jie, Wu, Yiling, Yao, Yaqi, Liu, Yang, Qi, Miao, Jin, Ying   +11 more
core   +1 more source

Solubilization and purification studies of GST-HBx-6His

, 2010
The Hepatitis B Virus X (HBx) protein is a protein expressed within an organism’s body infected with the Hepatitis B Virus (HBV). Its characterization in depth could develop an improved treatment for both acute and chronic Hepatitis B patients.
Goh, Kester Zhi Hao.
core  

[The E3 ubiquitin ligase KLHL8 degrades HBx protein via the ubiquitin-proteasome pathway and inhibits HBV cccDNA transcription]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Liu ZH, He XM, Zhao B, Li JQ, Xu KX, Yu HB, Chen J.   +6 more
europepmc   +1 more source

Sequential backbone chemical shift assignments of a cancer-associated isoform of the HBx protein from human hepatitis B virus. [PDF]

Biomol NMR Assign
Clavier A, Shida T, Droemer MA, Holzinger J, Schütz AK.   +4 more
europepmc   +1 more source

Multiple mechanisms of HBx in promoting chromosome instability

, 2017
The hepatitis B virus X protein (HBx) encoded in HBV genome has been implicated in development of hepatocellular carcinoma (HCC) by promoting centrosome aberration and chromosomal instability.
Ching, YP
core  

NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival.

, 2002
In this paper, we examined the cellular effect of hepatitits B virus X (HBx) in ChangX-34 cells, inducible HBx-expressing cells. High expression of HBx protein in ChangX-34 cells resulted in approximately three-fold increase in DNA synthesis and did not ...
Wang, JH, Lee, MO, Park, S, Um, HR, Lee, JH, Cho, H, Jin, YH, Yun, C   +7 more
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