Results 161 to 170 of about 3,362,872 (199)

Expression of HBx protein in hepatitis B virus-infected intrahepatic cholangiocarcinoma

open access: yesHepatobiliary and Pancreatic Diseases International, 2012
BACKGROUND: Hepatitis B virus (HBV) is an etiological factor of intrahepatic cholangiocarcinoma (ICC), but the pathogenic mechanisms remain unclear.
Yan-Ming Zhou, Zheng-Feng Yin
exaly   +5 more sources

HBx Protein Potentiates Hepatitis B Virus Reactivation

Molecular Biology, 2022
Hepatitis B virus (HBV) can cause chronic hepatitis B, one of the most prevalent infectious diseases in the world. Global estimates suggest that over 2 billion people are affected by HBV, with over 250 million people developing chronic infection. Upon treatment of comorbidities, patients with chronic infection may develop an abrupt increase of viral ...
S A, Brezgin   +9 more
openaire   +2 more sources

Structural characterization of an intrinsically unfolded mini-HBX protein from hepatitis B virus

open access: yesMolecules and Cells, 2012
The hepatitis B virus x protein (HBX) is expressed in HBV-infected liver cells and can interact with a wide range of cellular proteins. In order to understand such promiscuous behavior of HBX we expressed a truncated mini-HBX protein (named Tr-HBX ...
Kyou-Hoon Han   +2 more
exaly   +2 more sources

Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication [PDF]

open access: yesVirology, 2012
Robust hepatitis B virus (HBV) replication is stimulated by the regulatory HBx protein. HBx binds the cellular protein DDB1; however, the importance of this interaction for HBV replication remains unknown.
Betty Slagle   +2 more
exaly   +2 more sources

Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx-mediated apoptosis

Biochemical and Biophysical Research Communications, 2004
Understanding the function of the hepatitis B virus X protein (HBx) is fundamental to elucidating the underlying mechanisms of hepatitis and hepatocarcinogenesis caused by hepatitis B virus (HBV) infection. We identified heat shock protein 60 (Hsp60) as a novel cellular target of HBx by the combination of affinity purification and mass spectrometry ...
Yasuo, Tanaka   +11 more
openaire   +2 more sources

Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells

open access: yesOncogene, 2000
Hepatitis B virus X (HBx) protein implicated in the development of liver cancer may inhibit the function of p53 tumor suppressor protein through cytoplasmic retention of p53 protein.
Chawon Yun, Hyeseong Cho, Jae-Ho Lee
exaly   +2 more sources

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