Results 181 to 190 of about 3,362,872 (199)
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Hepatitis: Epigenetic control of HBV by HBx protein--releasing the break?

Nature reviews. Gastroenterology & hepatology, 2016
HBV persists by depositing covalently closed circular DNA (cccDNA) into the nucleus of infected host cells. HBV X protein (HBx) is a crucial determinant for regulating HBV activity, but the molecular details have not been fully understood. A new role for HBx in regulating cccDNA transcription has now been identified.
openaire   +2 more sources

Heat shock protein 60 binds to hepatitis B virus X protein (HBx) and enhances HBx-mediated apoptosis

Gastroenterology, 2003
Yasuo Tanaka   +7 more
openaire   +1 more source

HBx protein as a therapeutic target for functional cure of hepatitis B virus infection

Virology
Hepatitis B virus (HBV) is a major cause of acute and chronic liver disease and represents a major public health problem worldwide. Current antiviral therapies with nucleos(t)ide analogues can effectively suppressing viremia but are not curative, and have little or no impact upon the HBV cccDNA minichromosome or the portions of integrated HBV DNA ...
openaire   +2 more sources

Cotransactivation of the fos-promoter by HBx and mutant P53 protein

Journal of Cancer Research and Clinical Oncology, 1995
Stephan Schaefer   +4 more
openaire   +1 more source

Hepatitis B virus HBx protein impairs liver regeneration through enhanced expression of IL-6 in transgenic mice

Journal of Hepatology, 2013
Patrick Soussan   +2 more
exaly  

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