Results 111 to 120 of about 305,562 (334)
Oxytetracycline have the therapeutic efficiency in CD133+ HCC population through suppression CD133 expression by decreasing of protein stability of CD133 [PDF]
, 2018 Yeonhwa Song +4 more
openalex +1 more source
A Comparison of Biannual Two-Phase Low-Dose Liver CT and US for HCC Surveillance in a Group at High Risk of HCC Development [PDF]
, 2020 Jeong Hee Yoon +11 more
openalex +1 more source
KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression
Advanced Science, EarlyView.Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao +9 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a Kolmogorov–Arnold network (KAN)‐powered nanoplasmonic biosensing platform for ultrasensitive detection of small extracellular vesicles in serum, enabling highly accurate pancreatic cancer screening. The method achieves an area under the curve (AUC) of 0.99 in a large clinical cohort, offering a robust and interpretable deep ...
Jiaheng Zhu +21 more
wiley +1 more source
TAF2: A potential oncogene for hepatocellular carcinoma [PDF]
, 2017 Astrocyte Elevated Gene 1 (AEG1) is an oncogene for hepatocellular carcinoma (HCC). Its role in HCC pathogenesis has been well studied. A pan cancer analysis of gene expression in multiple databases identified TATA-box binding protein associated factor 2
Chidambaranathan Reghupaty, Saranya
core +1 more source
Comparable and Complimentary Modalities for Treatment of Small-Sized HCC: Surgical Resection, Radiofrequency Ablation, and Microwave Ablation [PDF]
, 2023 Jeffrey S. Wicks +7 more
openalex +1 more source
Advanced Science, EarlyView.This study identifies the unconventional role of CXCL2 in regulating neutrophil polarization and immune responses in HCC. Unlike the common view that CXCL2 acts mainly as an extracellular chemokine, intracellular CXCL2 can interact with YBX1 and prevent its nuclear translocation.
Xin Liu +13 more
wiley +1 more source
Cancer Management and Research, 2022 Wenqi Song,1,* Xuemei Zhang,2,* Lin Feng,1 Yongwei Lai,1 Tongtong Li,1 Pengxia Zhang1 1 Key Laboratory of Microecology-immune Regulatory Network and Related Diseases, School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang, People’s ...
Song W +5 more
doaj
Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders
Advanced Science, EarlyView.This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin +8 more
wiley +1 more source