Results 41 to 50 of about 400,342 (335)

Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]

open access: yes, 2018
It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P   +5 more
core   +1 more source

Hepatocellular carcinoma and multidrug resistance: Past, present and new challenges for therapy improvement [PDF]

open access: yes, 2015
Hepatocellular carcinoma (HCC) is the most common malignancy of the liver and the third cause of cancer death worldwide. Chronic hepatitis due to HBV and HCV infection are two major risk factors for HCC worldwide.
Cuestas, María Luján   +2 more
core   +1 more source

Hepatocellular Carcinoma (HCC) in Egypt: A comprehensive overview

open access: yesJournal of the Egyptian National Cancer Institute, 2020
Worldwide, hepatocellular carcinoma (HCC) is a universal problem and its epidemiological data showed variation from place to place. Hepatocellular carcinoma (HCC) is the sixth and fourth common cancer in worldwide and Egypt, respectively. Egypt ranks the
W. Rashed   +3 more
semanticscholar   +1 more source

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease [PDF]

open access: yes, 2016
Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we observed higher expression of Yap1/Ctgf axis in dysplastic nodules and HCC chemically-induced in F344 rats, genetically susceptible to hepatocarcinogenesis ...
Avila, Matias A.   +13 more
core   +2 more sources

Epigenetic silencing of miR-144/451a cluster contributes to HCC progression via paracrine HGF/MIF-mediated TAM remodeling

open access: yesMolecular Cancer, 2021
Background & Aims Hepatocellular carcinoma (HCC) is among the malignancies with the highest mortality. The key regulators and their interactive network in HCC pathogenesis remain unclear.
Jun-Long Zhao   +11 more
semanticscholar   +1 more source

NOTCH in HCC [PDF]

open access: yesScience-Business eXchange, 2011
Stanford researchers have shown that NOTCH activation can protect against hepatocellular carcinoma, adding to new findings that argue for ramping up NOTCH signaling to treat some cancers. The team plans to tease out the mechanisms by which NOTCH promotes some cancers and has antitumor effects in others.
openaire   +2 more sources

HCC: RNA-Sequencing in Cirrhosis

open access: yesBiomolecules, 2023
Hepatocellular carcinoma (HCC) ranks the most common types of cancer worldwide. As the fourth leading cause of cancer-related deaths, its prognosis remains poor. Most patients developed HCC on the basis of chronic liver disease. Cirrhosis is an important precancerous lesion for HCC. However, the molecular mechanisms in HCC development are still unclear.
Haoyu Wang   +7 more
openaire   +3 more sources

Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

open access: yesNature Communications, 2020
We report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific extracellular vesicle (EV) purification system for early detection of HCC by performing digital scoring on the purified EVs.
Na Sun   +34 more
semanticscholar   +1 more source

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

open access: yes, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
Altomonte, Jennifer   +9 more
core   +3 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

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