Results 71 to 80 of about 277,119 (298)

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

circ-CFH promotes the development of HCC by regulating cell proliferation, apoptosis, migration, invasion, and glycolysis through the miR-377-3p/RNF38 axis

Open Life Sciences, 2022
Circular RNAs (circRNAs) have previously been confirmed to function as vital regulators in multiple human cancers, including hepatocellular carcinoma (HCC). This study aimed to clarify the role and underlying molecular mechanisms of circ-CFH in HCC. circ-
Chen Zengyin, Du Juan, Yang Chen, Si Guangju, Chen Yuxin   +4 more
doaj   +1 more source

AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway

Cell Death and Disease, 2020
Hepatocellular carcinoma (HCC) is a major leading cause of cancer-related death worldwide. Alpha fetoprotein (AFP) is reactivated in a majority of hepatocellular carcinoma (HCC) and associated with poor patient outcomes.
Tianke Chen, Xiaowei Dai, Juji Dai, Chaodong Ding, Zheng Zhang, Ziqi Lin, Jin Hu, Mei Lu, Zhanyu Wang, Yalei Qi, Li Zhang, Rulu Pan, Zhu Zhao, Liting Lu, Wanqin Liao, Xincheng Lu   +15 more
semanticscholar   +1 more source

Medical therapy of HCC [PDF]

Journal of Hepatology, 2022
Vogel, Arndt, Saborowski, Anna
openaire   +3 more sources

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

Advanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng, Shiqiong Lei, Yiwei Zeng, Lian Chen, Jingqu Chen, Wei Fu, Yu Chen, Xinping Hu, Jing Wang, Meiyuan Jin, Zhichen Liu, Xiaofang Dai, Lei Liu, Wenshan He, Jiajing Zhou, Zhixing Lin, Frank Caruso, Jinghua Ren   +17 more
wiley   +1 more source

90Y-/166Ho- ‘Radiation lobectomy’ for liver tumors induces abnormal morphology and impaired drainage of peritumor lymphatics

JHEP Reports
Background & Aims: High-dose unilobar radioembolization, or ‘radiation lobectomy’ (RL), is an induction therapy that achieves contralateral future liver remnant hypertrophy while simultaneously irradiating the tumor.
Daan Andel, Lotte van den Bent, Marnix Gerard Ernest Hendrik Lam, Maarten Leonard Johannes Smits, Isaac Quintus Molenaar, Joep de Bruijne, Miangela Marie Laclé, Onno Kranenburg, Inne Hildbrand Max Borel Rinkes, Jeroen Hagendoorn   +9 more
doaj   +1 more source

M2 Macrophage–Derived Exosomes Facilitate HCC Metastasis by Transferring αMβ2 Integrin to Tumor Cells

Hepatology, 2020
The development and progression of hepatocellular carcinoma (HCC) is dependent on its local microenvironment. Tumor‐associated macrophages (TAMs) are deemed a key factor for the tumor microenvironment and attribute to contribute to tumor aggressiveness ...
Jindao Wu, W. Gao, Qiyun Tang, Yue Yu, Wei You, Zhengshan Wu, Ye Fan, Long Zhang, Chen Wu, Guoyong Han, X. Zuo, Yao-Yao Zhang, Zhiqiang Chen, Wenzhou Ding, Xiangcheng Li, Fengming Lin, Hongbing Shen, Jin-hai Tang, Yaqin Zhang, Xuehao Wang   +19 more
semanticscholar   +1 more source

Liver transplantation and waitlist mortality for HCC and non-HCC candidates following the 2015 HCC exception policy change [PDF]

American Journal of Transplantation, 2019
Historically, exception points for hepatocellular carcinoma (HCC) led to higher transplant rates and lower waitlist mortality for HCC candidates compared to non-HCC candidates. As of October 2015, HCC candidates must wait 6 months after initial application to obtain exception points; the impact of this policy remains unstudied.
Christine E. Haugen, Benjamin Philosophe, Jacqueline M. Garonzik Wang, Mary G. Bowring, Jessica M. Ruck, Shane Ottmann, Tanveen Ishaque, Tanveen Ishaque, Samantha E. Halpern, Andrew M. Cameron, Madeleine M. Waldram, Dorry L. Segev, Dorry L. Segev, Allan B. Massie, Allan B. Massie, Anne F. Rositch, Macey L. Henderson   +16 more
openaire   +3 more sources

Advances in Optical Techniques for Tumor Detection

Advanced Optical Materials, EarlyView.
Cancer detection is vital for patient survival. Optical technologies overcome conventional cytology's limitations with high sensitivity and molecular specificity. This review highlights five techniques: Raman spectroscopy, fluorescence sensors, fiber optic sensors, photoacoustic imaging, and colorimetric detection for tumor diagnosis via direct ...
Yang Yu, Anqi Yang, Jiaqi Liao, Julian Evans, Ruili Zhang, Shuang E, Sailing He   +6 more
wiley   +1 more source

Exploring Glypican-3 as a Molecular Target in Hepatocellular Carcinoma: Perspectives on Diagnosis and Precision Immunotherapy Strategies

Frontiers in Bioscience-Landmark
Liver cancer, primarily hepatocellular carcinoma (HCC), is the second leading cause of cancer-related deaths globally. It is typically characterized by rapid progression, poor prognosis, and high mortality rates.
Alireza Tojjari, Abdelrahman H. Hafez, Ali Saeed, Meghana Singh, Anwaar Saeed   +4 more
doaj   +1 more source