Structure-activity relationships of fluorene compounds inhibiting HCV variants [PDF]
, 2020 Approximately 71 million people suffer from hepatitis C virus (HCV) infection worldwide. Persistent HCV infection causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma, resulting in approximately 400,000 deaths ...
Gadhe, Changdev G. +10 more
core +1 more source
HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV‐Associated Pathogenesis [PDF]
Oxidative Medicine and Cellular Longevity, 2016 HCV (hepatitis C virus) is a member of the Flaviviridae family that contains a single‐stranded positive‐sense RNA genome of approximately 9600 bases. HCV is a major causative agent for chronic liver diseases such as steatosis, fibrosis, cirrhosis, and hepatocellular carcinoma which are caused by multifactorial processes.
Medvedev, Regina +2 more
openaire +2 more sources
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
, 2016 Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino +5 more
core +1 more source
Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan [PDF]
Clinical and Molecular HepatologyBackground/Aims Steatotic liver disease (SLD) is a common manifestation in chronic hepatitis C (CHC). Metabolic alterations in CHC are associated with metabolic dysfunction-associated steatotic liver disease (MASLD).
Chung-Feng Huang +14 more
doaj +1 more source
Matched population-based study examining the risk of type 2 diabetes in people with and without diagnosed hepatitis C virus infection [PDF]
, 2016 Meta-analyses have found hepatitis C virus (HCV) infection to be associated with an increased risk of type 2 diabetes mellitus (T2DM). Here, we examine this association within a large population-based study, according to RNA status.
Alexander +28 more
core +3 more sources
Canadian Medical Association Journal, 2014 We applaud Shah and colleagues[1][1] for raising the issue of establishing a Canadian screening program for hepatitis C. We agree that hepatitis C shows the hallmarks of an infectious disease suited to a screening program,[2][2] but we are concerned that the extrapolation of American data into ...
Fiona G, Kouyoumdjian +3 more
openaire +5 more sources
Central European Journal of Immunology, 2021 Chronic hepatitis C (CHC) affects the activity of natural killer (NK) cells, but successful interferon- free treatment partially restores it. The goal of this study was to assess whether gender influences NK functionality.
Agata Zientarska +8 more
doaj +1 more source
The prevalence of hepatitis C virus among people of South Asian origin in Glasgow: results from a community based survey and laboratory surveillance [PDF]
, 2013 Background South Asians often present late with HCV or HBV related liver disease which could have been avoided with early diagnosis and subsequent treatment; however the prevalence of HCV/HBV among South Asians in Glasgow is not known.
Ahmed, S. +14 more
core +2 more sources
Heart and Lung Transplants from HCV‐Infected Donors to Uninfected Recipients
New England Journal of Medicine, 2019 Background Hearts and lungs from donors with hepatitis C viremia are typically not transplanted. The advent of direct‐acting antiviral agents to treat hepatitis C virus (HCV) infection has raised the possibility of substantially increasing the donor ...
A. Woolley +14 more
semanticscholar +1 more source
Cryoglobulinemia and hepatitis C virus
Журнал инфектологии, 2014 The review presents recent data on cryoglobulinemiaassociated with a hepatitis C virus: prevalence, pathogenesis, clinical manifestations, laboratory diagnostics, approaches to therapy.
N. V. Dunaeva, E. V. Esaulenko
doaj +1 more source