Results 21 to 30 of about 273,364 (223)
Heart and Lung Transplants from HCV‐Infected Donors to Uninfected Recipients
New England Journal of Medicine, 2019 Background Hearts and lungs from donors with hepatitis C viremia are typically not transplanted. The advent of direct‐acting antiviral agents to treat hepatitis C virus (HCV) infection has raised the possibility of substantially increasing the donor ...
A. Woolley +14 more
semanticscholar +1 more source
The distribution of hepatitis C virus genotypes in patients with hepatocellular carcinoma
Asian Journal of Medical Sciences, 2019 Background: Hepatic cirrhosis develops within 20-30 years in approximately 20% of individuals chronically infected with hepatitis C virus (HCV). Aims and Objective: This study aimed to determine the distribution of HCV genotypes in patients with HCV ...
Ayfer Bakır +4 more
doaj +1 more source
Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence
Evolutionary Bioinformatics, 2008 The genome of the hepatitis C virus (HCV) exhibits a high genetic variability. This remarkable heterogeneity is mainly attributed to the gradual accumulation of mutational changes, whereas the contribution of recombination events to the evolution of HCV ...
R.S. Ross +5 more
doaj +1 more source
The Egyptian Journal of Internal Medicine, 2019 Background The recommended reliance on 12 weeks posttreatment sustained virological response (SVR12) instead of SVR24 was validated for treatment evaluation. Aim Judging claimed concordance between SVR12 and SVR24.
Maha M Elsabaawy +9 more
doaj +1 more source
Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection.
New England Journal of Medicine, 2014 BACKGROUND All-oral combination therapy is desirable for patients with chronic hepatitis C virus (HCV) infection. We evaluated daclatasvir (an HCV NS5A replication complex inhibitor) plus sofosbuvir (a nucleotide analogue HCV NS5B polymerase inhibitor ...
M. Sulkowski +23 more
semanticscholar +1 more source
From Well Structured Transition Systems to Program Verification [PDF]
EPTCS 320, 2020, pp. 44-49, 2020 We describe the use of the theory of WSTS for verifying programs.
arxiv +1 more source
Central European Journal of Immunology, 2021 Chronic hepatitis C (CHC) affects the activity of natural killer (NK) cells, but successful interferon- free treatment partially restores it. The goal of this study was to assess whether gender influences NK functionality.
Agata Zientarska +8 more
doaj +1 more source
Quantifying the relative contribution of free virus and cell-to-cell transmission routes to the propagation of hepatitis C virus infections in vitro using an agent-based model [PDF]
arXiv, 2021 Experiments have shown that hepatitis C virus (HCV) infections in vitro disseminate both distally via the release and diffusion of cell-free virus through the medium, and locally via direct, cell-to-cell transmission. To determine the relative contribution of each mode of infection to HCV dissemination, we developed an agent-based model (ABM) that ...
arxiv
The Pan African Medical Journal, 2015 Viral hepatitis during pregnancy is associated with high risk of maternal complications and has become a leading cause of foetal death. So the main objective of this study is to determine the prevalence of hepatitis C viral infections among pregnant ...
Yohannes Zenebe +3 more
doaj +1 more source
Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.
New England Journal of Medicine, 2014 BACKGROUND Effective treatment for hepatitis C virus (HCV) genotype 1 infection in patients who have not had a sustained virologic response to prior interferon-based therapy represents an unmet medical need.
N. Afdhal +24 more
semanticscholar +1 more source