Results 21 to 30 of about 276,656 (346)

Effect of combined siRNA of HCV E2 gene and HCV receptors against HCV [PDF]

open access: yesVirology Journal, 2011
Hepatitis C virus (HCV) is a major threat as almost 3% of the world's population (350 million individual) and 10% of the Pakistani population is chronically infected with this virus. RNA interference (RNAi), a sequence-specific degradation process of RNA, has potential to be used as a powerful alternative molecular therapeutic approach in spite of the ...
Bushra Ijaz   +7 more
openaire   +4 more sources

Comparative study on anti-HCV testing using plasma, dried plasma spots (DPS), and dried blood spots (DBS)Highlights

open access: yesBiosafety and Health, 2021
The aim of this study was to evaluate the performance of an assay using dried plasma spot (DPS) and dried blood spot (DBS) samples for the serological detection of anti-hepatitis C virus (HCV) antibodies.
Jieqiong Ma   +6 more
doaj  

The Immunohistochemical Staining of Vimentin and E-Cadherin in Bladder Cancer Patients Infected with Hepatitis C Virus

open access: yesJournal of Pure and Applied Microbiology, 2023
The invasion and spread of cancer cells are two of the most notable characteristics of malignant tumors. Recent studies suggest that the epithelial-mesenchymal transition (EMT) has been linked to this significant occurrence.
May K. Ismael   +3 more
doaj   +1 more source

Reduction of Liver Fibrosis After Treatment with Elbasvir/Grazoprevir in Patients with Hepatitis C Infection in Chronic Kidney Disease on Hemodialysis, a Quasi-Experimental Study

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2021
Background: Approximately 5-60% of hemodialysis patients have comorbid of hepatitis C virus (HCV) infection. The survival rate of hemodialysis patients HCV is lower than those without HCV due to the risk of liver fibrosis and cardiovascular disease.
Bayu Laksono   +4 more
doaj   +1 more source

Heart and Lung Transplants from HCV‐Infected Donors to Uninfected Recipients

open access: yesNew England Journal of Medicine, 2019
Background Hearts and lungs from donors with hepatitis C viremia are typically not transplanted. The advent of direct‐acting antiviral agents to treat hepatitis C virus (HCV) infection has raised the possibility of substantially increasing the donor ...
A. Woolley   +14 more
semanticscholar   +1 more source

The distribution of hepatitis C virus genotypes in patients with hepatocellular carcinoma

open access: yesAsian Journal of Medical Sciences, 2019
Background: Hepatic cirrhosis develops within 20-30 years in approximately 20% of individuals chronically infected with hepatitis C virus (HCV). Aims and Objective: This study aimed to determine the distribution of HCV genotypes in patients with HCV ...
Ayfer Bakır   +4 more
doaj   +1 more source

Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence

open access: yesEvolutionary Bioinformatics, 2008
The genome of the hepatitis C virus (HCV) exhibits a high genetic variability. This remarkable heterogeneity is mainly attributed to the gradual accumulation of mutational changes, whereas the contribution of recombination events to the evolution of HCV ...
R.S. Ross   +5 more
doaj   +1 more source

The correlation of HCV RNA and HCV core antigen in different genotypes of HCV [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2018
BackgroundTo analyze the correlation of HCV RNA and HCV core antigen (HCV cAg) in different genotypes of HCV.MethodsOne hundred and six patients who were diagnosed with HCV infection by HCV RNA test were included in the study. HCV genotypes were detected by PCR fluorescent probe.
Yu Xiang   +3 more
openaire   +3 more sources

Sustained virological response 12 versus sustained virological response 24 as evaluation endpoints in chronic hepatitis C virus Egyptian patients treated with sofosbuvir-based regimens

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Background The recommended reliance on 12 weeks posttreatment sustained virological response (SVR12) instead of SVR24 was validated for treatment evaluation. Aim Judging claimed concordance between SVR12 and SVR24.
Maha M Elsabaawy   +9 more
doaj   +1 more source

Gender as a factor affecting NK cell activity in patients successfully treated for chronic hepatitis C with direct-acting antivirals

open access: yesCentral European Journal of Immunology, 2021
Chronic hepatitis C (CHC) affects the activity of natural killer (NK) cells, but successful interferon- free treatment partially restores it. The goal of this study was to assess whether gender influences NK functionality.
Agata Zientarska   +8 more
doaj   +1 more source

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