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Heat shock proteins and effects of heat shock in plants
Plant Molecular Biology, 1982Soybean seedlings when exposed to a heat shock respond in a manner very similar to that exhibited by cultured cells, and reported earlier [2]. Maximum synthesis of heat shock proteins (HSPs) occurs at 40C. The heat shock response is maintained for a relatively short time under continuous high temperature.
M, Altschuler, J P, Mascarenhas
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Heat shock proteins in the kidney
Pediatric Nephrology, 2016Heat shock proteins (Hsps) are essential to cell survival through their function as protein chaperones. The role they play in kidney health and disease is varied. Hsp induction may be either beneficial or detrimental to the kidney, depending on the specific Hsp, type of cell, and context.
Rajasree, Sreedharan, Scott K, Van Why
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Parasitology Today, 1988
Many parasites, including most of those of medical or veterinary importance, experience a major increase in ambient temperature at some stage during their life cycle. This occurs when a cyst or free-living larval form is ingested by a warm-blooded host, when a poikilotherm-infecting parasite is transmitted to a homeotherm, or when a transiently free ...
G, Newport, J, Culpepper, N, Agabian
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Many parasites, including most of those of medical or veterinary importance, experience a major increase in ambient temperature at some stage during their life cycle. This occurs when a cyst or free-living larval form is ingested by a warm-blooded host, when a poikilotherm-infecting parasite is transmitted to a homeotherm, or when a transiently free ...
G, Newport, J, Culpepper, N, Agabian
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Current Opinion in Oncology, 2003
Heat shock protein 90 (Hsp90) is a molecular chaperone required for the stability and function of a number of conditionally activated and/or expressed signaling proteins, as well as multiple mutated, chimeric, or overexpressed signaling proteins, which promote cancer cell growth or survival or both.
Len, Neckers, S Percy, Ivy
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Heat shock protein 90 (Hsp90) is a molecular chaperone required for the stability and function of a number of conditionally activated and/or expressed signaling proteins, as well as multiple mutated, chimeric, or overexpressed signaling proteins, which promote cancer cell growth or survival or both.
Len, Neckers, S Percy, Ivy
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Neuroprotection: Heat Shock Proteins
Current Medical Research and Opinion, 2002Cells respond to external stresses such as metabolic disturbances and injuries, including cerebral ischaemia (stroke), in a very typical manner. The cell mounts a stress response that incorporates the induction of a number of genes encoding proteins which may act to save the cell from death.
Kelly, S, Yenari, MA
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Heat shock proteins in infection
Clinica Chimica Acta, 2019Heat shock proteins (HSPs) are constitutively expressed under physiological conditions in most organisms but their expression can significantly enhance in response to four types of stimuli including physical (e.g., radiation or heat shock), chemical and microbial (e.g., pathogenic bacteria, viruses, parasites and fungi) stimuli, and also dietary. These
Azam, Bolhassani, Elnaz, Agi
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Heat Shock Proteins; An Overview
Current Pharmaceutical Biotechnology, 2010Heat shock proteins (Hsps) protect protein substrates against conformational damage to promote the function of the proteins, prevent aggregation and prevent formation of toxic inclusion bodies. Protein aggregates and fibrils have been associated with neurodegenerative diseases and with inclusion bodies.
Lütfi, Tutar, Yusuf, Tutar
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The stress (heat shock) proteins
International Journal of Biochemistry, 1991When prokaryotic and eukaryotic cells are exposed to a variety of physiological stresses such as a nonlethal temperature (4&43”C) and heavy metals, the synthesis of most proteins is suppressed, but a small number of proteins are rapidly synthesized. This reaction is referred to as the “stress response” or “heat shock response” and the induced proteins ...
H, Itoh, Y, Tashima
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Heat Shock Proteins in Glioblastomas
Neurosurgery Clinics of North America, 2010Glioblastoma multiforme is the most common primary central nervous system tumor. The prognosis for these malignant brain tumors is poor, with a median survival of 14 months and a 5-year survival rate below 2%. Development of novel treatments is essential to improving survival and quality of life for these patients.
Isaac, Yang +2 more
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1990
The finding that tumor cells are more thermosensitive than their normal counterparts (1–4) prompted research on the effect of heat on normal and neoplastic cells. In 1970, the phenomenon of thermotolerance was described for the first time (5). Cells of L12l0 leukemia after being exposed to sublethal hyperthermia (52% of BDF1 mice survivors after ...
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The finding that tumor cells are more thermosensitive than their normal counterparts (1–4) prompted research on the effect of heat on normal and neoplastic cells. In 1970, the phenomenon of thermotolerance was described for the first time (5). Cells of L12l0 leukemia after being exposed to sublethal hyperthermia (52% of BDF1 mice survivors after ...
openaire +2 more sources