Insights Into the Role of Heat Shock Protein 27 in the Development of Neurodegeneration [PDF]
Frontiers in Molecular Neuroscience, 2022 Small heat shock protein 27 is a critically important chaperone, that plays a key role in several essential and varied physiological processes. These include thermotolerance, apoptosis, cytoskeletal dynamics, cell differentiation, protein folding, among ...
Bianka A. Holguin +2 more
doaj +4 more sources
Heat Shock Protein 27 Levels Predict Myocardial Inhomogeneities in Hemodialysis Patients [PDF]
Mediators of Inflammation, 2022 Background. Sudden cardiac death (SCD) is the single major cause of death in hemodialysis (HD) patients. QRS-T angle is an established marker of global repolarization heterogeneity associated with electrical instability and SCD.
Andrzej Jaroszyński +4 more
doaj +2 more sources
Schizothorax prenanti Heat Shock Protein 27 Gene: Cloning, Expression, and Comparison with Other Heat Shock Protein Genes after Poly (I:C) Induction [PDF]
Animals, 2022 We identified and cloned cDNA encoding the heat shock protein (Hsp) 27 gene from Schizothorax prenanti (SpHsp27), and compared its expression with that of SpHsp60, SpHsp70, and SpHsp90 in the liver, head kidney, hindgut, and spleen of S.
Jianlu Zhang +8 more
doaj +2 more sources
Mechanistic insights into heat shock protein 27, a potential therapeutic target for cardiovascular diseases [PDF]
Frontiers in Cardiovascular Medicine, 2023 Heat shock protein 27 (HSP27) is a small chaperone protein that is overexpressed in a variety of cellular stress states. It is involved in regulating proteostasis and protecting cells from multiple sources of stress injury by stabilizing protein ...
Yifei Zou +5 more
doaj +2 more sources
The Heat Shock Protein 27 Immune Complex Enhances Exosomal Cholesterol Efflux [PDF]
Biomedicines, 2020 Previously, we demonstrated that Heat Shock Protein 27 (HSP27) reduces the inflammatory stages of experimental atherogenesis, is released by macrophage (MΦ) exosomes and lowers cholesterol levels in atherosclerotic plaques.
Chunhua Shi +4 more
doaj +2 more sources
Heat Shock Protein 27 Affects Myeloid Cell Activation and Interaction with Prostate Cancer Cells [PDF]
Biomedicines, 2022 Heat shock proteins are cytoprotective molecules induced by environmental stresses. The small heat shock protein 27 (Hsp27) is highly expressed under oxidative stress conditions, mediating anti-oxidative effects and blocking apoptosis.
Debora Singer +3 more
doaj +2 more sources
Revisiting the Old Data of Heat Shock Protein 27 Expression in Squamous Cell Carcinoma: Enigmatic HSP27, More Than Heat Shock [PDF]
Cells, 2022 Initially discovered to be induced by heat shock, heat shock protein 27 (HSP27, also called HSPB1), a member of the small HSP family, can help cells better withstand or avoid heat shock damage.
Shutao Zheng +6 more
doaj +2 more sources
Profile of Serum Heat Shock Protein-27 Level in Patients with Salivary Gland Tumor [PDF]
Journal of Dentistry, 2022 Statement of the Problem: Heat shock protein 27 (HSP27) plays important roles in many cellular processes and has been implicated in different types of diseases such as cancers.Purpose: This study aimed to evaluate the serum level of HSP27 in patients ...
Negar Moghadasi +6 more
doaj +2 more sources
Heat Shock Protein 27 in Radiation-Induced Trismus: Mechanistic Insights and a Hypothesis-Generating Framework [PDF]
BiomedicinesRadiation-induced trismus (RIT) is a common and function-limiting late complication of radiotherapy for head and neck cancers, particularly when the masticatory muscles and temporomandibular joint receive high doses.
Erkan Topkan +5 more
doaj +2 more sources
The Role of Heat Shock Protein 27 in Carcinogenesis and Treatment of Colorectal Cancer. [PDF]
Curr Pharm Des, 2022 Abstract: The incidence of colorectal cancer (CRC) has significantly increased in recent decades, which has made this disease an important global health issue. Despite many efforts, there is no useful prognostic or diagnostic biomarker for CRC. Heat shock protein 27 (Hsp27) is one of the most studied members of Hsp family.
Asgharzadeh F +2 more
europepmc +3 more sources