Results 31 to 40 of about 7,838,486 (292)
Heat shock proteins in tendinopathy: novel molecular regulators [PDF]
, 2012 Tendon disorders-tendinopathies-are the primary reason for musculoskeletal consultation in primary care and account for up to 30% of rheumatological consultations.
Neal L. Millar +3 more
core +1 more source
Heat shock protein 27 phosphorylation state is associated with cancer progression
Frontiers in Genetics, 2014 Understanding the mechanisms that control stress-induced survival is critical to explain how tumors frequently resist to treatment and to improve current anti-cancer therapies.
Maria eKatsogiannou +11 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011 Endogenous heat shock proteins (HSPs) 70 and 25/27 are induced in renal cells by injury from energy depletion. Transfected over-expression of HSPs 70 or 27 (human analogue of HSP25), provide protection against renal cell injury from ATP deprivation. This study examines whether over-expressed HSP27 depends on induction of endogenous HSPs, in particular ...
Sreedharan, R. +5 more
openaire +2 more sources
Inhibition of Daxx-Mediated Apoptosis by Heat Shock Protein 27 [PDF]
Molecular and Cellular Biology, 2000 Heat shock protein 27 (HSP27) confers cellular protection against a variety of cytotoxic stresses and also against physiological stresses associated with growth arrest or receptor-mediated apoptosis. Phosphorylation modulates the activity of HSP27 by causing a major change in the supramolecular organization of the protein, which shifts from oligomers ...
S J, Charette +3 more
openaire +2 more sources
Interaction of human heat shock protein 70 with tumor-associated peptides [PDF]
, 2009 Molecular chaperones of the heat shock protein 70 (Hsp70) family play a crucial role in the presentation of exogenous antigenic peptides by antigen-presenting cells (APCs).
Manzenrieder, Florian +20 more
core +1 more source
Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA [PDF]
, 1994 Mitochondrial heat shock protein 70 (mt-Hsp70) has been shown to play an important role in facilitating import into, as well as folding and assembly of nuclear-encoded proteins in the mitochondrial matrix.
Herrmann, Johannes M. +3 more
core +2 more sources
Cells, 2021 Heterogeneity of glia in different CNS regions may contribute to the selective vulnerability of neuronal populations in neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS).
Rebecca San Gil +4 more
doaj +1 more source
Retinal Preconditioning and the Induction of Heat-Shock Protein 27
Investigative Opthalmology & Visual Science, 2003 Brief periods of ischemia have been shown to protect the retina from potentially damaging periods of ischemia. This phenomenon has been termed ischemic preconditioning or ischemic tolerance. In the present study the cellular changes in levels of heat shock protein (Hsp)27, -70, and -90 mRNA and expression of Hsp in the rat retina associated with ...
Yan, Li +4 more
openaire +2 more sources
Heat Shock Protein 27 Mediated Signaling in Viral Infection [PDF]
Biochemistry, 2012 Heat shock proteins (HSPs) play a critical role in many intracellular processes, including apoptosis and delivery of other proteins to intracellular compartments. Small HSPs have been shown previously to participate in many cellular functions, including IL-8 induction. Human adenovirus infection activates intracellular signaling, involving particularly
Jaya, Rajaiya +4 more
openaire +2 more sources
Heat Shock Protein 27 Enhances SUMOylation of Heat Shock Protein B8 to Accelerate the Progression of Breast Cancer [PDF]
The American Journal of Pathology, 2020 Heat shock proteins (HSPs) are emerging as valuable potential molecular targets in breast cancer therapy owing to their diverse functions in cancer cells. This study investigated the potential role of heat shock protein 27 (HSP27, also known as HSPB1) in breast cancer through heat shock protein B8 (HSPB8).
Shuai, Wang +5 more
openaire +2 more sources