Results 21 to 30 of about 7,838,486 (292)

Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives [PDF]

Journal of Medicinal Chemistry, 2009
Inhibitors of heat-induced heat shock protein 70 (HSP70) expression have the potential to enhance the therapeutic effectiveness of heat-induced radiosensitization of tumors. Among known small molecule inhibitors, quercetin has the advantage of being easily modified for structure-activity studies.
Rongsheng E, Wang, Jeffrey L-F, Kao, Carolyn A, Hilliard, Raj K, Pandita, Joseph L, Roti Roti, Clayton R, Hunt, John-Stephen, Taylor   +6 more
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Heat shock protein 27 in osteoblasts.

Folia Pharmacologica Japonica, 2002
Physiological stresses such as heat stress, chemical stress and mechanical stress induce the expression of heat shock protein (HSP) families in cells, which affects cell function. In the present review, we describe HSP27, a small HSP in osteoblasts, especially the regulatory mechanism of the induction of HSP27 stimulated by physiological bone agents ...
KOZAWA, Osamu, TOKUDA, Haruhiko
openaire   +3 more sources

Functional Characterization of the Small Heat Shock Protein Hsp12p from Candida albicans [PDF]

, 2012
Hsp12p is considered to be a small heat shock protein and conserved among fungal species. To investigate the expression of this heat shock protein in the fungal pathogen Candida albicans we developed an anti-CaHsp12p antibody.
Mühlschlegel, Fritz A., Fritz A. Mühlschlegel, De Sordi Luisa, Luisa De Sordi (146209), Fritz A. Mühlschlegel (146212), Fu Man-Shun, De Sordi, L, Fu, Man Shun, Fu, MS, Fritz A Mühlschlegel, Man-Shun Fu, Luisa De Sordi, Mühlschlegel Fritz A., De Sordi, Luisa, Mühlschlegel, FA, Luisa De Sordi¤b, Man-Shun Fu (146203)   +16 more
core   +1 more source

Late onset distal hereditary motor neuropathy type IIB (dHMN IIB) – case reports

Aktualności Neurologiczne, 2018
Distal hereditary motor neuropathies are a heterogeneous group of rare, genetically determined neuromuscular disorders. Distal hereditary motor neuropathy type IIB is an autosomal dominant disorder, and the onset of symptoms is observed in adulthood ...
Mateusz Spławski, Katarzyna Broniarek, Robert Bonek   +2 more
doaj   +1 more source

HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation. [PDF]

PLoS ONE, 2016
Heat shock proteins belong to a conserved protein family and are involved in multiple cellular processes. Heat shock protein 27 (Hsp27), also known as heat HSPB1, participates in cellular responses to not only heat shock, but also oxidative or chemical ...
Hongxing Ye, Hongguang Huang, Fei Cao, Mantao Chen, Xiujue Zheng, Renya Zhan   +5 more
doaj   +1 more source

Translation Regulation and RNA Granule Formation after Heat Shock of Procyclic Form Trypanosoma brucei: Many Heat-Induced mRNAs Are also Increased during Differentiation to Mammalian-Infective Forms. [PDF]

PLoS Neglected Tropical Diseases, 2016
African trypanosome procyclic forms multiply in the midgut of tsetse flies, and are routinely cultured at 27°C. Heat shocks of 37°C and above result in general inhibition of translation, and severe heat shock (41°C) results in sequestration of mRNA in ...
Igor Minia, Clementine Merce, Monica Terrao, Christine Clayton   +3 more
doaj   +1 more source

Cooling the Fire of Atherosclerosis With Heat Shock Protein 27

Journal of the American College of Cardiology, 2013
Heat shock proteins (HSPs) may lie at this juncture, as they modulate immune responses, cytotoxicity, and oxidative stress. This class of proteins was discovered in the 1960s and initially described as inducing transient resistance to cell death in response to increasing temperature (2).
Weintraub, Neal L., Rubinstein, Jack
openaire   +2 more sources

DISRUPTION OF EXPRESSION OF MRNA HSP27 AND UBIQUITIN AS A MECHANISM OF ESCAPING OF JURKAT LINE TUMOR CELLS FROM APOTOSIS

Бюллетень сибирской медицины, 2015
The research objective is to establish the link between heat shock protein 27 and ubiquitin mRNA expression as well as Jukart tumor cell apoptosis.The method of flow cytofluorometry has been used to evaluate apoptosis realization using FITC-labeled ...
O. L. Nosareva, Ye. A. Stepovaya, N. V. Ryazantseva, Ye. V. Zakirova, I. O. Mazunin, L. S. Litvinova, N. A. Sokhonevich, O. N. Vesnina, Ye. V. Shakhristova   +8 more
doaj   +1 more source

Studies of Heat shock protein 27 Interactions [PDF]

Acta Crystallographica Section A Foundations and Advances, 2014
Human heat shock protein 27 (Hsp27) is an oligomeric and cell survival protein that has been associated with several cancers including prostrate and breast cancer. It's a known anti-apoptotic protein that functions as a molecular chaperone for several proteins.
Adeleke Aguda, Nham Nguyen, Sami Caner, Susan Moore, Barbara Lelj-Garolla, Amina Zoubeidi, Martin Gleave, Gary Brayer   +7 more
openaire   +1 more source

Regulation by Heat Shock Protein 27 of Osteocalcin Synthesis in Osteoblasts [PDF]

Endocrinology, 2011
We have previously reported that various stimuli, including sphingosine 1-phosphate, are able to induce heat shock protein (HSP) 27 in osteoblast-like MC3T3-E1 cells. However, the precise role of HSP27 in bone metabolism has not been satisfactory clarified.
Kenji, Kato, Seiji, Adachi, Rie, Matsushima-Nishiwaki, Chiho, Minamitani, Hideo, Natsume, Yasuo, Katagiri, Yoshinobu, Hirose, Jun, Mizutani, Haruhiko, Tokuda, Osamu, Kozawa, Takanobu, Otsuka   +10 more
openaire   +2 more sources