Results 41 to 50 of about 7,838,486 (292)

Heat Shock Protein 27(HSP27) in Kidney Disease: Potentials for Diagnosis and Therapy [PDF]

Journal of Advanced Pharmacy Research, 2017
The small HSP27 is an actin-specific molecular chaperone involved in cytoskeleton architecture, cell migration, metabolism, survival, growth/differentiation, mRNA stabilization, and tumor progression.
Shahenda Mahgoub
doaj   +1 more source

Anti-Vpr Activities of Heat Shock Protein 27

Molecular Medicine, 2007
HIV-1 Vpr plays a pivotal role in viral pathogenesis and is preferentially targeted by the host immune system. In this report, we demonstrate that a small heat shock protein, HSP27, exhibits Vpr-specific antiviral activity, as its expression is specifically responsive to vpr gene expression and increased levels of HSP27 inhibit Vpr-induced cell cycle ...
Dong, Liang, Zsigmond, Benko, Emmanuel, Agbottah, Michael, Bukrinsky, Richard Y, Zhao   +4 more
openaire   +2 more sources

What's in a Name?: Heat Shock Protein 27 and Keratinocyte Differentiation [PDF]

Journal of Investigative Dermatology, 2010
In this issue of the Journal, Robitaille and colleagues present data supporting a role for the small heat shock protein (HSP) 27 in keratinocyte terminal differentiation. This adds to the growing literature implicating HSP27 as a regulator of biologic function beyond thermal stress response.
Bektas, Meryem, Rubenstein, David S.
openaire   +2 more sources

Association of Neonatal Asphyxia With Serum Levels of Heat Shock Protein 27 in a Small Sample of Newborns

Acta Medica Iranica, 2019
Neonatal asphyxia is a state of hypoxia and hypercapnia caused by failure to breathe spontaneously and regularly soon after birth. Heat shock proteins (HSPs) are a ubiquitous and diverse group of highly conserved proteins which are rapidly up-regulated ...
Ahmadshah Farhat, Mojtaba Shafiee, Ashraf Mohammadzadeh, Reza Saeidi, Rana Amiri, Majid Ghayour-Mobarhan   +5 more
doaj   +1 more source

Is brain gliosis a characteristic of chronic methamphetamine use in the human?

Neurobiology of Disease, 2014
Animal data show that high doses of the stimulant drug methamphetamine can damage brain dopamine neurones; however, it is still uncertain whether methamphetamine, at any dose, is neurotoxic to human brain.Since gliosis is typically associated with brain ...
Junchao Tong, Paul Fitzmaurice, Yoshiaki Furukawa, Gregory A. Schmunk, Dennis J. Wickham, Lee-Cyn Ang, Allan Sherwin, Tina McCluskey, Isabelle Boileau, Stephen J. Kish   +9 more
doaj   +1 more source

Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]

, 2007
Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias, Christoph Sucker, Zacharowski, Kai, Hartmann, Matthias, Kai Zacharowski, Matthias Thielmann, Sucker, Christoph, Sucker Christoph, Thielmann Matthias, Matthias Hartmann, Zacharowski Kai, Hartmann Matthias   +11 more
core   +1 more source

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Virók Dezső, Gönczöl Éva, Prohászka Zoltán, Burián, Katalin, Endrész Valéria, Duba Jenő, Füst György, Kis, Zoltán, Virók, Dezső, Endrész, Valéria, Duba, Jenő, Boda, Krisztina, Berencsi Klára, Berencsi, Klára, Kis Zoltán, Romics, László, Romics László, Gönczöl, Éva, Prohászka, Zoltán, Horváth, Laura, Boda Krisztina, Burián Katalin, Horváth Laura, Füst, György   +23 more
core   +2 more sources

Serum heat shock protein 27 levels predict cardiac mortality in hemodialysis patients

BMC Nephrology, 2018
Background Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as well as to evaluate factors ...
Andrzej Jaroszyński, Anna Jaroszyńska, Tomasz Zaborowski, Anna Drelich-Zbroja, Tomasz Zapolski, Wojciech Dąbrowski   +5 more
doaj   +1 more source

Prospective determination of heat shock protein serum levels in Saskatchewan women during pregnancyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: The stress proteins, heat shock protein 27, heat shock protein 70, and αB-crystallin, have all been detected in human serum under normal and disease conditions.
Lindsey Broberg, MD, Ewa I. Miskiewicz, PhD, Jocelyne Martel, MD, Daniel J. MacPhee, PhD   +3 more
doaj   +1 more source

Serum Heat Shock Protein 27 Is Increased in Chronic Pancreatitis and Pancreatic Carcinoma

, 2011
Objectives: A prior study suggested serum heat shock protein 27 (HSP27) as a potential marker for pancreatic carcinoma, but its accuracy in differentiating cancer from chronic pancreatitis was not evaluated. We aimed to analyze HSP27 levels in pancreatic
LIAO, WEI-CHIH;WU, MING-SHIANG;WANG, HSIU-PO;TIEN, YU-WEN;LIN, JAW-TOWN, 廖偉智;吳明賢;王秀伯;田郁文;林肇堂   +1 more
core   +1 more source