Results 51 to 60 of about 7,838,486 (292)

Heat Shock Protein 27 Phosphorylation Regulates Tumor Cell Migration under Shear Stress

Biomolecules, 2019
Heat shock protein 27 (HSP27) is a multifunctional protein that undergoes significant changes in its expression and phosphorylation in response to shear stress stimuli, suggesting that it may be involved in mechanotransduction.
Baohong Zhang, Fei Xie, Aziz ur Rehman Aziz, Shuai Shao, Wang Li, Sha Deng, Xiaoling Liao, Bo Liu   +7 more
doaj   +1 more source

A Charcot-Marie-Tooth-Causing Mutation in HSPB1 Decreases Cell Adaptation to Repeated Stress by Disrupting Autophagic Clearance of Misfolded Proteins

Cells, 2022
Charcot-Marie-Tooth (CMT) disease is the most common inherited neurodegenerative disorder with selective degeneration of peripheral nerves. Despite advances in identifying CMT-causing genes, the underlying molecular mechanism, particularly of selective ...
Xuelian Zhang, Yaru Qiao, Ronglin Han, Yingjie Gao, Xun Yang, Ying Zhang, Ying Wan, Wei Yu, Xianchao Pan, Juan Xing   +9 more
doaj   +1 more source

Comparison of heat-shock responses between the hydrothermal vent shrimp Rimicaris exoculata and the related coastal shrimp Palaemonetes varians [PDF]

, 2010
The deep-sea vent shrimp Rimicaris exoculata is believed to occur at the hot end of the hydrothermal biotope in order to provide essential elements to its epibiosis. Because it is found close to hot venting water, R.
Thomas Chertemps, Sven Thatje, Shillito, Bruce, Leger, Nelly, Bruce Shillito, Nelly Léger, Chertemps, Thomas, Thatje, Sven, Ravaux, Juliette, Delphine Cottin, Cottin, Delphine, Juliette Ravaux   +11 more
core   +1 more source

Androgen receptor and heat shock protein 27 co-regulate the malignant potential of molecular apocrine breast cancer

Journal of Experimental & Clinical Cancer Research, 2018
Background The most striking feature of molecular apocrine breast cancer (MABC) is the expression of androgen receptor (AR). We report here the mechanism of the AR in regulating the behavior of MABC.
Xiaozhen Liu, Changyun Feng, Junjun Liu, Lu Cao, Guomin Xiang, Fang Liu, Shuling Wang, Jiao Jiao, Yun Niu   +8 more
doaj   +1 more source

Heat shock induces rapid resorption of primary cilia [PDF]

, 2012
Primary cilia are involved in important developmental and disease pathways, such as the regulation of neurogenesis and tumorigenesis. They function as sensory antennae and are essential in the regulation of key extracellular signalling systems.
Ashworth, R, Prodromou, NV, Osborn, DP, Chapple, JP, Beales, PL, Knight, MM, Thompson, CL, Cogger, KF   +7 more
core   +1 more source

Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma

BMC Cancer, 2009
Background Recent proteomic studies identified Hsp27 as a highly over-expressed protein in oral squamous cell carcinoma (OSCC). Clinical studies that attempted to evaluate the prognostic values of Hsp27 yielded inconsistent results, which may be due to ...
Peng Tingsheng, Ye Hui, Sheng Shihu, Liu Xiqiang, Wang Anxun, Shi Fei, Crowe David L, Zhou Xiaofeng   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children [PDF]

, 2014
A previous survey for clinical cases of Buruli ulcer (BU) in the Mapé Basin of Cameroon suggested that, compared to older age groups, very young children may be less exposed to Mycobacterium ulcerans.
Miriam Bolz, Arianna Andreoli, Pritchard, James, Yeboah-Manu, Dorothy, Amanda Ross, Gerd Pluschke, Jacques C. Minyem (421866), Amanda Ross (187821), Alphonse Um Boock (267187), Ross, Amanda, James Pritchard, Katharina Röltgen, Dorothy Yeboah-Manu (120059), Jacques C. Minyem, Eric Koka, Um Boock, Alphonse, Kobina A. Ampah, Ampah, Kobina A., Andreoli, Arianna, Samuel Y. Aboagye, Noumen, Djeunga, Kobina A Ampah, Martin W. Bratschi (309715), Djeunga Noumen (421870), Bolz, Miriam, Miriam Bolz (309717), Aboagye, Samuel Y., Alphonse Um Boock, James Pritchard (543790), A Ross, Röltgen, Katharina, Bratschi, Martin W., Gerd Pluschke (7855), Katharina Röltgen (120045), Minyem, Jacques C., Martin W Bratschi, Djeunga Noumen, Eric Koka (567714), Koka, Eric, Dorothy Yeboah-Manu, Kobina A. Ampah (567713), Jacques C Minyem, Martin W. Bratschi, Samuel Y. Aboagye (567712), Arianna Andreoli (543789), Pluschke, Gerd, Samuel Y Aboagye   +46 more
core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Corpora Amylacea and Heat Shock Protein 27 in Ammon's Horn Sclerosis [PDF]

Journal of Neuropathology & Experimental Neurology, 2000
Increased numbers of corpora amylacea have been observed in the resected mesial temporal lobe of many patients with complex partial seizures (CPS) and Ammon's horn sclerosis (AHS). Several heat shock proteins (HSPs) are induced by seizures and have been suggested as an etiologic factor in the formation corpora amylacea.
Erdamar, S, Zhu, ZQ, Hamilton, WJ, Armstrong, DL, Grossman, RG   +4 more
openaire   +2 more sources