Bio‐Inspired Artificial Ionic Mechanoreceptor
A skin‐inspired artificial mechanoreceptor based on ionic interactions is presented for biomimetic tactile sensing. Pressure‐driven ionic redistribution within microfluidic channels generates a self‐powered electrical signal without external bias. The generated waveform exhibits mechanoreceptor‐like temporal features, including overshoot and undershoot,
Mohammad Akbari +4 more
wiley +1 more source
ANALYSIS OF CELLULAR SENTINELS FOR EXTRACELLULAR HEAT SHOCK PROTEIN-PEPTIDE COMPLEXES [PDF]
Since the discovery of gp96 in the 1980’s as a “tumor rejection antigen,” Heat Shock Proteins (HSPs) have received attention from immunologists for their ability to prime immune responses.
Messmer, Michelle
core
Melanin content directly controls fungal spore mechanical properties, with pigmented spores achieving rupture forces two orders of magnitude higher than hyaline spores. Environmental stress drives this quantity‐quality tradeoff; stressed species invest energy in melanin‐reinforced, mechanically superior thick‐walled, super‐hydrophobic spores, while ...
Atul Agrawal, Steven E. Naleway
wiley +1 more source
Expression of Heat Shock Protein 27 in Human Atherosclerotic Plaques and Increased Plasma Level of Heat Shock Protein 27 in Patients With Acute Coronary Syndrome [PDF]
Background— We intended to identify proteins that are differentially expressed in human atherosclerotic plaques. Methods and Results— Comparative 2-dimensional electrophoretic analysis on carotid atherosclerotic endarterectomy ...
Haing Kee, Park +14 more
openaire +2 more sources
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation [PDF]
Introduction The prolactin-Janus-kinase-2-signal transducer and activator of transcription-5 (JAK2-STAT5) pathway is essential for the development and functional differentiation of the mammary gland.
Liu, R. +26 more
core +2 more sources
Genetically Programmed Shape‐Morphing of Engineered Living Materials
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker +7 more
wiley +1 more source
Heat Shock Protein 27 Associates with Basolateral Cell Boundaries in Heat-Shocked and ATP-Depleted Epithelial Cells [PDF]
Heat stress alters epithelial barrier function, and heat stress preconditioning protects epithelial function from injury. Hsp27 is a small stress protein that has previously been shown to modulate actin assembly. Thus, by regulating actin filaments associated with cell junctions, hsp27 could alter epithelial function.
Eric A, Shelden +3 more
openaire +2 more sources
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley +1 more source
Heat shock protein 27 (HSP27) is traditionally viewed as an intra-cellular chaperone protein with anti-apoptotic properties. However, recent data indicate that a number of heat shock proteins, including HSP27, are also found in the extra-cellular space ...
Zarah Batulan +7 more
doaj +1 more source
In Silico Screening Studies on Methanesulfonamide Derivatives as Dual Hsp27 and Tubulin Inhibitors Using QSAR and Molecular Docking [PDF]
The expression of heat shock protein 27 (Hsp27) as a chaperone protein, is increased in response to various stress stimuli such as anticancer chemotherapy. This phenomenon can lead to survive of the cells and causes drug resistance.
A. Mostoufi +3 more
doaj +1 more source

