Results 11 to 20 of about 870,730 (334)
Thermodynamics of Heat Shock Response [PDF]
Physical Review Letters, 1999 Production of heat shock proteins are induced when a living cell is exposed to a rise in temperature. The heat shock response of protein DnaK synthesis in E.coli for temperature shifts from temperature T to T plus 7 degrees, respectively to T minus 7 ...
A. Gragarov +19 more
core +6 more sources
The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells. [PDF]
PLoS ONE, 2013 The heat shock response (HSR) is a highly conserved molecular response to various types of stresses, including heat shock, during which heat-shock proteins (Hsps) are produced to prevent and repair damages in labile proteins and membranes.
Zohar Bromberg +3 more
doaj +2 more sources
Roles of heat shock factor 1 beyond the heat shock response
Cellular and Molecular Life Sciences, 2018 Various stress factors leading to protein damage induce the activation of an evolutionarily conserved cell protective mechanism, the heat shock response (HSR), to maintain protein homeostasis in virtually all eukaryotic cells. Heat shock factor 1 (HSF1) plays a central role in the HSR. HSF1 was initially known as a transcription factor that upregulates
János Barna, P. Csermely, T. Vellai
semanticscholar +4 more sources
The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
Cells, 2021 Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses.
Ariadni Androvitsanea +3 more
doaj +1 more source
BMC Genomics, 2021 Background Psychrotrophic lactic acid bacteria (LAB) species are the dominant species in the microbiota of cold-stored modified-atmosphere-packaged food products and are the main cause of food spoilage. Despite the importance of psychrotrophic LAB, their
Ilhan Cem Duru +5 more
doaj +1 more source
Heat shock response of spirochetes [PDF]
Infection and Immunity, 1991 We examined the heat shock response of the pathogenic spirochetes Treponema pallidum, Borrelia burgdorferi, and Leptospira interrogans and certain saprophytic spirochetes. Cellular proteins synthesized after shifts to higher temperatures were [35S]methionine labeled and analyzed by gel electrophoresis and fluorography. Only T.
L V, Stamm +3 more
openaire +3 more sources
Transient intracellular acidification regulates the core transcriptional heat shock response
eLife, 2020 Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou +3 more
doaj +1 more source
Is there a role for HSF1 in viral infections?
FEBS Open Bio, 2022 Cells undergo numerous processes to adapt to new challenging conditions and stressors. Heat stress is regulated by a family of heat shock factors (HSFs) that initiate a heat shock response by upregulating the expression of heat shock proteins (HSPs ...
Antonia Reyes +4 more
doaj +1 more source
Transcriptomic Adaptation of Legionella pneumophila to Transient Heat Shock
Frontiers in Water, 2022 A natural inhabitant of freshwater microbial ecology, Legionella pneumophila is an opportunistically pathogenic bacteria that has found a niche in hot water distribution systems (HWDS) where it challenges hospitals with the spread of nosocomial infection.
Jeffrey Liang, Sebastien P. Faucher
doaj +1 more source
Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively. [PDF]
PLoS ONE, 2014 Stationary-phase cultures have been used as an important model of aging, a complex process involving multiple pathways and signaling networks. However, the molecular processes underlying stress response of non-dividing cells are poorly understood ...
Inbal Nussbaum +4 more
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