Results 81 to 90 of about 252,628 (301)
Journal of Pharmacological Sciences, 2013 It is generally accepted that an increase in the myocardial level of heat-shock protein 72 (HSP72) protects viable cardiac tissue against myocardial infarction (MI)-induced stress.
Tetsuro Marunouchi +4 more
doaj +1 more source
Frontiers in Physiology, 2020 Heat shock proteins are molecular chaperones that are involved in numerous normal cellular processes and stress responses, and heat shock factors are transcriptional activators of heat shock proteins.
Jisu Jin +7 more
doaj +1 more source
Dynamic association of transcriptional activation domains and regulatory regions in Saccharomyces cerevisiae heat shock factor [PDF]
, 2002 In Saccharomyces cerevisiae, the heat shock transcription factor (HSF) is thought to be a homotypic trimer that is bound to the promoters of heat shock protein (HSP) genes at both normal and heat shock temperatures.
Chen, Tianxin, Parker, Carl S.
core
Some Like It Hot, Some Like It Warm: Phenotyping To Explore Thermotolerance Diversity [PDF]
, 2012 Plants have evolved overlapping but distinct cellular responses to different aspects of high temperature stress. These responses include basal thermotolerance, short- and long-term acquired thermotolerance, and thermotolerance to moderately high ...
Charng, Y. Y. +3 more
core +2 more sources
Binding of heat shock factor to and transcriptional activation of heat shock genes inDrosophila
Nucleic Acids Research, 1995 Heat shock factor (HSF) binds to heat shock elements (HSEs) and the binding can be highly cooperative. Here we report an analysis of binding of Drosophila HSF to both native and synthetic heat shock regulatory regions. We find that cooperative binding of HSF requires close proximity, rather than helical alignment, of HSEs.
M, Fernandes, H, Xiao, J T, Lis
openaire +3 more sources
Activation of heat-shock transcription factor 1 by hypertonic shock in 3T3 cells [PDF]
Biochemical Journal, 1996 The exposure of 3T3 cells to a medium made hypertonic by the addition of NaCl induced activation of a heat-shock transcription factor (HSF). This activation, as monitored by gel-mobility-shift assays, occurred within 10 min of hypertonic shock and was dose-dependent in relation to the osmotic strength of the medium up to 0.7 osM.
ALFIERI, Roberta +3 more
openaire +2 more sources
IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury
Advanced Science, EarlyView.IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang +18 more
wiley +1 more source
Analysis of heat shock transcription factor gene family in cocoa
Pesquisa Agropecuária TropicalThe heat shock factor (HSF) is crucial for plant stress regulation. This study aimed to analyze the role and characteristics of the HSF protein in Theobroma cacao L. The assesment was carried out bioinformatically, consisting of
Waki’atil Rosida +2 more
doaj +1 more source
Journal of Inflammation, 2011 Poly (ADP-ribose) polymerase-1 (PARP-1) is a highly conserved multifunctional enzyme, and its catalytic activity is stimulated by DNA breaks. The activation of PARP-1 and subsequent depletion of nicotinamide adenine dinucleotide (NAD+) and adenosine ...
Zingarelli Basilia +4 more
doaj +1 more source
Heat shock transcription factor 1-deficiency attenuates overloading-associated hypertrophy of mouse soleus muscle. [PDF]
PLoS ONE, 2013 Hypertrophic stimuli, such as mechanical stress and overloading, induce stress response, which is mediated by heat shock transcription factor 1 (HSF1), and up-regulate heat shock proteins (HSPs) in mammalian skeletal muscles.
Tomoyuki Koya +13 more
doaj +1 more source