Contribution of time of day and the circadian clock to the heat stress responsive transcriptome in Arabidopsis. [PDF]
, 2019 In Arabidopsis, a large subset of heat responsive genes exhibits diurnal or circadian oscillations. However, to what extent the dimension of time and/or the circadian clock contribute to heat stress responses remains largely unknown.
Blair, Emily J +6 more
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Recent Advances in Genetic and Epigenetic Modulation of Animal Exposure to High Temperature
Frontiers in Genetics, 2020 Animals have evolved multiple systems, including genetic and epigenetic systems, to respond accordingly to heat exposure and heat acclimation. Heat exposure greatly affects immunity, changes metabolic processes, and poses a serious threat to animals ...
Jiong Wu +3 more
doaj +1 more source
The Plant Heat Stress Transcription Factors (HSFs): Structure, Regulation, and Function in Response to Abiotic Stresses [PDF]
, 2016 Abiotic stresses such as high temperature, salinity and drought adversely affect the survival, growth and reproduction of plants. Plants respond to such unfavorable changes through developmental, physiological and biochemical ways, and these responses ...
De-Xu Luo +5 more
core +10 more sources
Identifying gene regulatory modules of heat shock response in yeast
BMC Genomics, 2008 Background A gene regulatory module (GRM) is a set of genes that is regulated by the same set of transcription factors (TFs). By organizing the genome into GRMs, a living cell can coordinate the activities of many genes in response to various internal ...
Li Wen-Hsiung, Wu Wei-Sheng
doaj +1 more source
A guide to heat shock factors as multifunctional transcriptional regulators
The FEBS JournalThe heat shock factors (HSFs) form a family of transcription factors, which are evolutionarily conserved in eukaryotes. They are best known as transcriptional regulators of molecular chaperone genes, including those encoding heat shock proteins, in response to heat shock and other protein‐damaging stresses.
Hendrik S. E. Hästbacka +3 more
openaire +2 more sources
The proteostasis network and its decline in ageing
, 2019 Ageing is a major risk factor for the development of many diseases, prominently including neurodegenerative disorders such as Alzheimer disease and Parkinson disease.
Hartl, F., Hipp, M., Kasturi, P.
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Heat shock induces rapid resorption of primary cilia [PDF]
, 2012 Primary cilia are involved in important developmental and disease pathways, such as the regulation of neurogenesis and tumorigenesis. They function as sensory antennae and are essential in the regulation of key extracellular signalling systems.
Anckar +32 more
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Agronomy, 2018 We investigated the role of heat shock transcription factors (Hsfs) during induction of defense response by heat-shock treatment (HST) in tomato. Leaf disease symptoms were significantly reduced at 12 and 24 h after HST, consistent with upregulation of ...
Nur Akbar Arofatullah +4 more
doaj +1 more source
Heat shock transcription factor 1 preserves cardiac angiogenesis and adaptation during pressure overload [PDF]
, 2008 To examine how heat shock transcription factor 1 (HSF1) protects against maladaptive hypertrophy during pressure overload, we subjected HSF1 transgenic (TG), knockout (KO) and wild type (WT) mice to a constriction of transverse aorta (TAC), and found ...
Aijun Sun +16 more
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Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans [PDF]
, 2019 Target of rapamycin (TOR) signaling is an evolutionarily well-conserved pathway that regulates various physiologic processes, including aging and metabolism. One of the key downstream components of TOR signaling is ribosomal protein S6 kinase (S6K) whose
daeeun jeong +5 more
core +1 more source