Chromatin landscape dictates HSF binding to target DNA elements.
Sequence-specific transcription factors (TFs) are critical for specifying patterns and levels of gene expression, but target DNA elements are not sufficient to specify TF binding in vivo.
Michael J Guertin, John T Lis
doaj +1 more source
The Skn7 Response Regulator of \u3ci\u3eSaccharomyces cerevisiae\u3c/i\u3e Interacts with Hsf1 In Vivo and Is Required for the Induction of Heat Shock Genes by Oxidative Stress [PDF]
The Skn7 response regulator has previously been shown to play a role in the induction of stress-responsive genes in yeast, e.g., in the induction of the thioredoxin gene in response to hydrogen peroxide.
Erkine, Alexander M. +6 more
core +1 more source
Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity [PDF]
We report the transcriptional response of Escherichia coli MG1655 to damage induced by colicins E3 and E9, bacteriocins that kill cells through inactivation of the ribosome and degradation of chromosomal DNA, respectively. Colicin E9 strongly induced the
Hinton, Jay C. D. +6 more
core +2 more sources
Aging cellular networks: chaperones as major participants
We increasingly rely on the network approach to understand the complexity of cellular functions. Chaperones (heat shock proteins) are key "networkers", which have among their functions to sequester and repair damaged protein. In order to link the network
Agoston +56 more
core +1 more source
De novo transcriptome analysis of Viola ×wittrockiana exposed to high temperature stress.
Around the world, pansies are one of the most popular garden flowers, but they are generally sensitive to high temperatures, and this limits the practicality of planting them during the warmest days of the year.
Xiaohua Du +5 more
doaj +1 more source
Heat shock transcription factors demonstrate a distinct mode of interaction with mitotic chromosomes. [PDF]
Price RM +5 more
europepmc +1 more source
The RootScope: A Simple High-Throughput Screening System For Quantitating Gene Expression Dynamics In Plant Roots [PDF]
Background: High temperature stress responses are vital for plant survival. The mechanisms that plants use to sense high temperatures are only partially understood and involve multiple sensing and signaling pathways.
Kaplinsky, Nicholas J. +4 more
core +1 more source
Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries [PDF]
The nuclear topography of splicing snRNPs, mRNA transcripts and chromosome domains in various mammalian cell types are described. The visualization of splicing snRNPs, defined by the Sm antigen, and coiled bodies, revealed distinctly different ...
A Monneron +64 more
core +1 more source
Transcriptional Modulation of Heat-Shock Protein Gene Expression
Heat-shock proteins (Hsps) are molecular chaperones that are ubiquitously expressed but are also induced in cells exposed to stressful stimuli. Hsps have been implicated in the induction and propagation of several diseases.
Anastasis Stephanou, David S. Latchman
doaj +1 more source
Living organisms alter their gene-expression patterns to withstand stressful conditions. Drought, salinity, heat and chilling are potent abiotic stresses causing an alteration in gene expression. Among these, high temperature stress stimulates Heat Shock
M K Chandra Prakash +2 more
doaj +1 more source

