Results 71 to 80 of about 238,370 (203)

Nuclear tau and its potential role in Alzheimer’s disease [PDF]

open access: yes, 2016
Tau protein, found in both neuronal and non-neuronal cells, forms aggregates in neurons that constitutes one of the hallmarks of Alzheimer’s disease (AD).
Al-Hilaly, Youssra   +2 more
core   +2 more sources

Chloroplast Signaling Gates Thermotolerance in Arabidopsis

open access: yesCell Reports, 2018
Summary: Temperature is a key environmental variable influencing plant growth and survival. Protection against high temperature stress in eukaryotes is coordinated by heat shock factors (HSFs), transcription factors that activate the expression of ...
Patrick J. Dickinson   +10 more
doaj   +1 more source

Evidence for a heat shock transcription factor-independent mechanism for heat shock induction of transcription in Saccharomyces cerevisiae. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1990
Transcription of the DNA damage-responsive gene, DDRA2, of Saccharomyces cerevisiae is activated by heat shock treatment as well as by mutagen/carcinogen exposure. Deletion analysis of upstream noncoding sequence indicated that sequences between approximately -190 and -140 base pairs were necessary for heat shock and DNA damage regulation of ...
N, Kobayashi, K, McEntee
openaire   +2 more sources

AXR3 and SHY2 interact to regulate root hair development [PDF]

open access: yes, 2003
Signal transduction of the plant hormone auxin centres on the regulation of the abundance of members of the Aux/IAA family of transcriptional regulators, of which there are 29 in Arabidopsis.
Grierson, C.S., Knox, K., Leyser, O.
core   +2 more sources

A Novel Heat Shock Element (HSE) in Entamoeba histolytica that Regulates the Transcriptional Activation of the EhPgp5 Gene in the Presence of Emetine Drug

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Transcriptional regulation of the multidrug resistance EhPgp5 gene in Entamoeba histolytica is induced by emetine stress. EhPgp5 overexpression alters the chloride-dependent currents that cause trophozoite swelling, diminishing induced programmed cell ...
Alma Nieto   +4 more
doaj   +1 more source

Activation of heat shock transcription factor in yeast is not influenced by the levels of expression of heat shock proteins [PDF]

open access: yesMolecular Microbiology, 2001
Heat shock transcription factor (HSF) transiently induces the expression of a universally conserved set of proteins, the heat shock proteins (Hsps), when cells are exposed to elevated temperatures as well as to a wide range of other environmental stresses.
B, Hjorth-Sørensen   +4 more
openaire   +2 more sources

Candida albicans pathogenicity mechanisms [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Alonso-Monge R   +10 more
core   +1 more source

Mechanisms of heat tolerance in crop plants

open access: yesBiologia Plantarum, 2015
Due to possible climate changes, heat stress has obtained a serious concern all over the world. Tolerance to this stress via knowledge of metabolic pathways will help us in engineering heat tolerant plants.
B. Asthir
doaj   +1 more source

Binding of heat shock factor to and transcriptional activation of heat shock genes inDrosophila

open access: yesNucleic Acids Research, 1995
Heat shock factor (HSF) binds to heat shock elements (HSEs) and the binding can be highly cooperative. Here we report an analysis of binding of Drosophila HSF to both native and synthetic heat shock regulatory regions. We find that cooperative binding of HSF requires close proximity, rather than helical alignment, of HSEs.
M, Fernandes, H, Xiao, J T, Lis
openaire   +3 more sources

Activation of heat-shock transcription factor 1 by hypertonic shock in 3T3 cells [PDF]

open access: yesBiochemical Journal, 1996
The exposure of 3T3 cells to a medium made hypertonic by the addition of NaCl induced activation of a heat-shock transcription factor (HSF). This activation, as monitored by gel-mobility-shift assays, occurred within 10 min of hypertonic shock and was dose-dependent in relation to the osmotic strength of the medium up to 0.7 osM.
ALFIERI, Roberta   +3 more
openaire   +2 more sources

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