Results 51 to 60 of about 238,370 (203)

Heat shock transcription factor activates transcription of the yeast metallothionein gene. [PDF]

Molecular and Cellular Biology, 1991
In the yeast Saccharomyces cerevisiae, transcription of the metallothionein gene CUP1 is induced by copper and silver. Strains with a complete deletion of the ACE1 gene, the copper-dependent activator of CUP1 transcription, are hypersensitive to copper. These strains have a low but significant basal level of CUP1 transcription.
P, Silar, G, Butler, D J, Thiele
openaire   +2 more sources

Circuit architecture explains functional similarity of bacterial heat shock responses

, 2012
Heat shock response is a stress response to temperature changes and a consecutive increase in amounts of unfolded proteins. To restore homeostasis, cells upregulate chaperones facilitating protein folding by means of transcription factors (TF).
Ala Trusina, Gamer J, Lopez-Larrea C, Maaloe O, Masayo Inoue, Namiko Mitarai, Neidhardt F C, Wetzstein M   +7 more
core   +1 more source

Heat shock proteins in health and disease: therapeutic targets or therapeutic agents? [PDF]

, 2001
For many years, heat shock or stress proteins have been regarded as intracellular molecules that have a range of housekeeping and cytoprotective functions, only being released into the extracellular environment in pathological situations such as necrotic
Pockley, A.G.
core   +1 more source

NTR1 is involved in heat stress tolerance through mediating expression regulation and alternative splicing of heat stress genes in Arabidopsis

Frontiers in Plant Science, 2023
As a common adverse environmental factor, heat stress (HS) not only drastically changes the plant transcriptome at the transcription level but also increases alternative splicing (AS), especially intron retention (IR) events.
Lei He, Qi Wu, Ye Jin, Ye Fan, Huazhong Shi, Huazhong Shi, Yizhong Wang, Wannian Yang   +7 more
doaj   +1 more source

The Yeast and Mammalian Ras Pathways Control Transcription of Heat Shock Genes Independently of Heat Shock Transcription Factor [PDF]

Molecular and Cellular Biology, 1994
Yeast strains in which the Ras-cyclic AMP (cAMP) pathway is constitutively active are sensitive to heat shock, whereas mutants in which the activity of this pathway is low are hyperresistant to heat shock. To determine the molecular basis for these differences, we examined the transcriptional induction of heat shock genes in various yeast strains ...
Engelberg, D., Zandi, E., Parker, C. S., Karin, M.   +3 more
openaire   +4 more sources

Proteotoxic stress reprograms the chromatin landscape of SUMO modification [PDF]

, 2015
The small ubiquitin-like modifier 2 (SUMO-2) is required for survival when cells are exposed to treatments that induce proteotoxic stress by causing the accumulation of misfolded proteins.
Anne Seifert, Geoffrey J. Barton, Pietà Schofield, Ronald T. Hay, Tanaka   +4 more
core   +3 more sources

Research Progress on Responses and Regulatory Mechanisms of Plants Under High Temperature

Current Issues in Molecular Biology
Global warming has resulted in an increase in the frequency of extreme high-temperature events. High temperatures can increase cell membrane permeability, elevate levels of osmotic adjustment substances, reduce photosynthetic capacity, impair plant ...
Jinling Wang, Yaling Wang, Hetian Jin, Yingzi Yu, Kai Mu, Yongxiang Kang   +5 more
doaj   +1 more source

Complex expression of murine heat shock transcription factors

Nucleic Acids Research, 1995
A central step in the transcriptional activation of heat shock genes is the binding of the heat shock factor (HSF) to upstream heat shock elements (HSEs). In vertebrates, HSF1 mediates the ubiquitous response to stress stimuli, while the role of a second HSE-binding factor, HSF2, is still unclear. In this work we show that both factors are expressed in
FIORENZA, Maria Teresa, FARKAS T., DISSING M., KOLDING D., ZIMARINO V.   +4 more
openaire   +3 more sources

The Role of Heat Shock Factors in Stress-Induced Transcription [PDF]

, 2011
Heat shock proteins (HSPs) are rapidly induced after stresses, such as heat shock, and accumulate at high concentrations in cells. HSP induction involves a family of heat shock transcription factors that bind the heat shock elements of the HSP genes and mediate transcription in trans. We discuss methods for the study of HSP binding to HSP promoters and
Yue, Zhang, Shiuh-Dih, Chou, Ayesha, Murshid, Thomas L, Prince, Sheila, Schreiner, Mary Ann, Stevenson, Stuart K, Calderwood   +6 more
openaire   +2 more sources

Mechanisms of heat sensing and responses in plants. It is not all about Ca2+ ions

Biologia Plantarum, 2018
The climate shift has resulted in frequent heat waves, which cause damaging effects on plant growth and development at different life stages. All cellular processes in plants are highly sensitive to a high temperature.
M. Sajid, B. Rashid, Q. Ali, T. Husnain
doaj   +1 more source