Characteristics and Regulating Roles of Wheat TaHsfA2-13 in Abiotic Stresses
Heat shock transcription factor (Hsf) exists widely in eukaryotes and responds to various abiotic stresses by regulating the expression of downstream transcription factors, functional enzymes, and molecular chaperones.
Xiangzhao Meng +10 more
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Heat Shock Response, Heat Shock Transcription Factor and Cell Aging
A characteristic feature of aging is a progressive impairment in the ability to adapt to environmental challenges. The purpose of this article is to review the evidence of an attenuated response to heat and physiological stresses in a number of mammalian aging model systems, including the human diploid fibroblasts in culture, whole animals and animal ...
Y K, Lee, D, Manalo, A Y, Liu
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Hopf bifurcation in a gene regulatory network model: Molecular movement causes oscillations [PDF]
Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes.
Chaplain, M, Ptashnyk, M, Sturrock, M
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Background Elevated temperature as a result of global climate warming, either in form of sudden heatwave (heat shock) or prolonged warming, has profound effects on the growth and development of plants.
Li Wang +9 more
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Regulation of cyclooxygenase-2 expression by heat: a novel aspect of heat shock factor 1 function in human cells. [PDF]
The heat-shock response, a fundamental defense mechanism against proteotoxic stress, is regulated by a family of heat-shock transcription factors (HSF). In humans HSF1 is considered the central regulator of heat-induced transcriptional responses.
Antonio Rossi +4 more
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Activation of Heat Shock Transcription Factor 1 in Atherosclerosis [PDF]
Previous work established that increased expression of heat shock proteins (HSPs) in the vessel wall might evoke proinflammatory and autoimmune reactions in the pathogenesis of atherosclerosis. The present study was designed to further scrutinize the molecular mechanisms of HSP expression involving activation of heat shock transcription factors (HSFs ...
Bernhard, Metzler +6 more
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Vectors for N- or C-terminal positioning of the yeast Gal4p DNA binding or activator domains [PDF]
EMTREE drug terms: fungal protein; heat shock protein 90; hybrid protein; transcription factor EMTREE medical terms: amino terminal sequence; article; carboxy terminal sequence; DNA binding; DNA binding domain; expression vector; Gal4p domain; gene ...
Millson, S. H. +2 more
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Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. [PDF]
BACKGROUND: Maintenance of cell fate determination requires the Polycomb group for repression; the trithorax group for gene activation; and the enhancer of trithorax and Polycomb (ETP) group for both repression and activation.
Brock, Hugh W +4 more
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Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rsp5, and Hsf1 in Candida albicans [PDF]
Peer reviewedPublisher ...
Cowen, Leah E., Leach, Michelle D.
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Heat Shock Factor 1 Is a Transcription Factor of Fas Gene
In mammalian cells, stress-induced expression of heat shock protein is controlled by heat shock factor 1 (HSF1). However, HSF1 functions as a regulator of additional genes. In this study, we observed that heat treatment effectively induced expression of Fas.
E, Shunmei +6 more
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