Results 31 to 40 of about 120,262 (257)

Heat Shock Factor 1 Is a Transcription Factor of Fas Gene

Molecules and Cells, 2010
In mammalian cells, stress-induced expression of heat shock protein is controlled by heat shock factor 1 (HSF1). However, HSF1 functions as a regulator of additional genes. In this study, we observed that heat treatment effectively induced expression of Fas.
E, Shunmei, Yuanbo, Zhao, Yunhong, Huang, Kun, Lai, Cha, Chen, Jianming, Zeng, Jiangying, Zou   +6 more
openaire   +2 more sources

Transcription Regulation of HYPK by Heat Shock Factor 1

PLoS ONE, 2014
HYPK (Huntingtin Yeast Partner K) was originally identified by yeast two-hybrid assay as an interactor of Huntingtin, the protein mutated in Huntington's disease. HYPK was characterized earlier as an intrinsically unstructured protein having chaperone-like activity in vitro and in vivo.
Srijit Das, Nitai Pada Bhattacharyya
openaire   +4 more sources

Differential recognition of heat shock elements by members of the heat shock transcription factor family [PDF]

The FEBS Journal, 2009
Heat shock transcription factor (HSF), an evolutionarily conserved stress response regulator, forms trimers and binds to heat shock element (HSE), comprising at least three continuous inverted repeats of the sequence 5′‐nGAAn‐3′. The single HSF of yeast is also able to bind discontinuously arranged nGAAn units.
Noritaka, Yamamoto, Yukiko, Takemori, Mayumi, Sakurai, Kazuhisa, Sugiyama, Hiroshi, Sakurai   +4 more
openaire   +2 more sources

Differential expression of heat shock transcription factors and heat shock proteins after acute and chronic heat stress in laying chickens (Gallus gallus). [PDF]

PLoS ONE, 2014
Heat stress due to high environmental temperature negatively influences animal performances. To better understand the biological impact of heat stress, laying broiler breeder chickens were subjected either to acute (step-wisely increasing temperature ...
Jingjing Xie, Li Tang, Lin Lu, Liyang Zhang, Lin Xi, Hsiao-Ching Liu, Jack Odle, Xugang Luo   +7 more
doaj   +1 more source

HSF1 Can Prevent Inflammation following Heat Shock by Inhibiting the Excessive Activation of the ATF3 and JUN&FOS Genes

Cells, 2022
Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is activated by proteotoxic agents and participates in the regulation of cellular stress response.
Patryk Janus, Paweł Kuś, Natalia Vydra, Agnieszka Toma-Jonik, Tomasz Stokowy, Katarzyna Mrowiec, Bartosz Wojtaś, Bartłomiej Gielniewski, Wiesława Widłak   +8 more
doaj   +1 more source

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Nature Communications, 2016
The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in ...
Michelle D. Leach, Rhys A. Farrer, Kaeling Tan, Zhengqiang Miao, Louise A. Walker, Christina A. Cuomo, Robert T. Wheeler, Alistair J. P. Brown, Koon Ho Wong, Leah E. Cowen   +9 more
doaj   +1 more source

Genome-wide identification and classification of the Hsf and sHsp gene families in Prunus mume, and transcriptional analysis under heat stress [PDF]

PeerJ, 2019
The transcriptional activation of heat shock proteins (Hsps) by heat shock transcription factors (Hsfs) is presumed to have a pivotal role in plant heat stress (HS) response.
Xueli Wan, Jie Yang, Cong Guo, Manzhu Bao, Junwei Zhang   +4 more
doaj   +2 more sources

Changes in the transcriptome of morula-stage bovine embryos caused by heat shock: relationship to developmental acquisition of thermotolerance

Reproductive Biology and Endocrinology, 2013
Background While initially sensitive to heat shock, the bovine embryo gains thermal resistance as it progresses through development so that physiological heat shock has little effect on development to the blastocyst stage by Day 5 after insemination ...
Sakatani Miki, Bonilla Luciano, Dobbs Kyle B, Block Jeremy, Ozawa Manabu, Shanker Savita, Yao JiQiang, Hansen Peter J   +7 more
doaj   +1 more source

The Yeast and Mammalian Ras Pathways Control Transcription of Heat Shock Genes Independently of Heat Shock Transcription Factor [PDF]

Molecular and Cellular Biology, 1994
Yeast strains in which the Ras-cyclic AMP (cAMP) pathway is constitutively active are sensitive to heat shock, whereas mutants in which the activity of this pathway is low are hyperresistant to heat shock. To determine the molecular basis for these differences, we examined the transcriptional induction of heat shock genes in various yeast strains ...
Engelberg, D., Zandi, E., Parker, C. S., Karin, M.   +3 more
openaire   +4 more sources

Research Progress on Responses and Regulatory Mechanisms of Plants Under High Temperature

Current Issues in Molecular Biology
Global warming has resulted in an increase in the frequency of extreme high-temperature events. High temperatures can increase cell membrane permeability, elevate levels of osmotic adjustment substances, reduce photosynthetic capacity, impair plant ...
Jinling Wang, Yaling Wang, Hetian Jin, Yingzi Yu, Kai Mu, Yongxiang Kang   +5 more
doaj   +1 more source