Results 91 to 100 of about 7,306,204 (405)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Sprinkling cattle for control of heat stress

open access: yesCalifornia Agriculture, 1973
Sprinkling cattle, under shades, during the summer in the Imperial Valley for 1 minute every 30 minutes when the temperature was above 80°F (27°C)—resulted in significantly higher feed consumption and rate of gain, compared with cattle under shades but ...
S Morrison, R Givens, G Lofgreen
doaj  

A comparative analysis of accelerating humid and dry heat stress in India

open access: yesEnvironmental Research Communications
Extreme humid heat stress poses distinct challenges to human health and productivity that cannot be mitigated solely by heat action plans designed for dry heat stress. This study investigates the trends in extreme heat stress, differentiating between dry
Jency Maria Sojan, Jayaraman Srinivasan
doaj   +1 more source

Transcriptome analysis of the role of autophagy in plant response to heat stress.

open access: yesPLoS ONE, 2021
Autophagy plays a critical role in plant heat tolerance in part by targeting heat-induced nonnative proteins for degradation. Autophagy also regulates metabolism, signaling and other processes and it is less understood how the broad function of autophagy
Yan Zhang   +4 more
doaj   +1 more source

Heat stress-induced transposon activation correlates with 3D chromatin organization rearrangement in Arabidopsis

open access: yesNature Communications, 2020
In higher eukaryotes, heterochromatin is mainly composed of transposable elements (TEs) silenced by epigenetic mechanisms. But, the silencing of certain heterochromatin-associated TEs is disrupted by heat stress.
Linhua Sun   +8 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effects of Drought, Heat and Their Interaction on the Growth, Yield and Photosynthetic Function of Lentil (Lens culinaris Medikus) Genotypes Varying in Heat and Drought Sensitivity

open access: yesFrontiers in Plant Science, 2017
Rising temperatures and drought stress limit the growth and production potential of lentil (Lens culinaris Medikus), particularly during reproductive growth and seed filling.
Akanksha Sehgal   +6 more
doaj   +1 more source

Ractopamine HCl improved cardiac hypertrophy but not poor growth, metabolic inefficiency, or greater white blood cells associated with heat stress in concentrate-fed lambs [PDF]

open access: yes, 2019
Heat stress decreases livestock performance and well-being (Hahn, 1999; Nienaber and Hahn, 2007), causes metabolic dysfunction that decreases growth efficiency (O’Brien et al., 2010), and alters cardiovascular function (Crandall et al., 2008). Each year,
Beede, Kristin A.   +6 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Heat stress adaptations in pigs [PDF]

open access: yesAnimal Frontiers, 2018
Heat stress adaptations in ...
Mayorga, Edith   +4 more
openaire   +4 more sources

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