Aging orchestrates a dWAT–MCP‐1–CCR2 axis that recruits and reprograms macrophage subpopulations, disrupting the local M1/M2 balance and suppressing WNT signaling, thereby impairing both hair cycle transition and production of genes associated with melanogenesis.
Jian Chen +13 more
wiley +1 more source
Pleomorphism in Soft Tissue Sarcomas: Molecular Characteristics and Clinical Features. [PDF]
Kopantseva EE +8 more
europepmc +1 more source
Dysglycaemia and Autonomic Dysfunction: The Diabetes Prevention Program Outcomes Study
ABSTRACT Aim Limited data on the link between various measures of glycemia and metabolism and autonomic dysfunction exist. We assessed the association of fasting plasma glucose [FPG], glycated haemoglobin [HbA1C], fasting insulin, and HOMA‐IR and cardiac autonomic function measures separately for men and women in the Diabetes Prevention Program ...
Justin B. Echouffo‐Tcheugui +12 more
wiley +1 more source
Unravelling therapeutic resistance: role of cancer stem cell and microRNA in metastatic prostate cancer. [PDF]
Moondra H +5 more
europepmc +1 more source
ABSTRACT Background & Aims Laterality disorders are rare congenital conditions caused by disruption of left–right embryonic patterning, often associated with ciliary dysfunction. Despite the identification of numerous causative genes, the molecular basis remains unresolved in many patients.
Alina Kurolap +19 more
wiley +1 more source
Targeting NOTCH-immune crosstalk in gliomas: from mechanisms to therapeutics. [PDF]
Ebrahimi S +6 more
europepmc +1 more source
Lung cancer stem cells in the tumor microenvironment: translational biomarkers and therapeutic strategies for immune evasion and treatment resistance. [PDF]
Shao LL +6 more
europepmc +1 more source
Molecular insights into uterine fibroids: crosstalk between SHH and Wnt pathways, DNA methylation, and miRNAs regulation. [PDF]
Purcino GMD +4 more
europepmc +1 more source
Mitophagy-driven immune evasion in skin cancer: multidimensional regulatory networks and context-dependent therapeutic strategies-a narrative review. [PDF]
Lv J, Liu G.
europepmc +1 more source
Evaluation of Itraconazole as a repurposed small molecule inhibitor of EMT in breast cancer: a molecular docking and dynamics study. [PDF]
Gayam PKR, Kulkarni AM, Aranjani JM.
europepmc +1 more source

