Results 131 to 140 of about 58,542 (264)

CMKLR1/PKA signaling reinforces sonic hedgehog pathway to promote medulloblastoma pathogenesis. [PDF]

Oncogenesis
Wang S, Jiang T, Wang T, Yang Z, Wang T, Zhang X, Gou X, Jia L, Wang L, Song Y.   +9 more
europepmc   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma. [PDF]

Sci Rep
Wang HG, Lu MX, Sheng ML, Lou YB, Xiao YC, Guo A, Yu ZH.   +6 more
europepmc   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Hedgehog pathway, cell cycle, and primary cilium. [PDF]

Cell Death Discov
Zhuang T.
europepmc   +1 more source

From sagittal to sprawled: Clavicular co‐option and the evolution of forelimb mechanics in talpines

Journal of Anatomy, EarlyView.
Forelimb posture in Eulipotyphla divides into sagittal and sprawled groups with distinct scapular and clavicular orientations. First true rib strength scales with body mass, reflecting vertical ground reaction forces, whereas clavicular strength reflects differences in medially directed forces on the pectoral girdle, especially pronounced in highly ...
Shin‐ichi Fujiwara, Hiroaki Saito
wiley   +1 more source

STK38-mediated feedback loop regulation of the hedgehog pathway governing tumor heterogeneity in renal papillary carcinoma. [PDF]

Cell Death Dis
Du Y, Sui X, Zheng Z, Zhang Z, Liu B, Bai Y, Zhao Y, Wu Q, Wu H, Zhong M, Li L, Sun H, Shao C.   +12 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Analyzing Hedgehog pathway-related genes: insights into breast cancer tumor microenvironment and prognostic implications. [PDF]

Front Immunol
Wang Z, Wang H.
europepmc   +1 more source

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source