Results 141 to 150 of about 1,302,226 (294)

From Evolutionary Genomics to Conservation Action: Gibbon as a System for Integrative Primate Genomics

Integrative Zoology, EarlyView.
This review synthesizes gibbon genomic research to propose a framework from evolutionary reconstruction and multidimensional vulnerability assessment to conservation intervention and long‐term dynamic monitoring. We clarify the supporting role of genomic evidence in conservation decision‐making and delineate a practicable pathway for integrating ...
Hangyu Tian, Pengfei Fan, Dongdong Wu
wiley   +1 more source

Genome-wide analysis of gene expression and alternative splicing in human medulloblastoma [PDF]

, 2010
Medulloblastoma is a malignant embryonal tumour of the cerebellum which most commonly affects children. A subset of tumours is thought to arise from cerebellar granule cell precursors (GCPs) that fail to undergo normal neuronal development, following ...
Menghi, F.
core  

Microplate Tectonics Through Earth History and Across Solid Multispheres

Geological Society of China Bulletin, EarlyView.
The evolution of tectonic microplates throughout Earth´s history as well as the transitions between microplates across different solid spheres offers a novel approach to expanding the traditional plate tectonics theory. ABSTRACT The evolution of tectonic microplates throughout Earth's history as well as the transitions between microplates across ...
Sanzhong Li, Yanhui Suo, Jie Zhou, Guozheng Sun, Jianping Zhou, Xianzhi Cao, Bo Liu, Lingli Guo, Zhaoxia Jiang, Qianqian Li, Shujuan Zhao, Long Chen, Xi Wang, Jun Hu, Xiaohui Li, Xiyao Li, Wenyong Duan, Lin Liu, Jie Liu, Guangzeng Wang, Pengcheng Wang, Qingbin Guan, Dingshan Deng, Xu Han, Liangliang Wang, Zihao Hu, Qiuling Liu, Heda Wang, Zihan Tian, Hans‐Peter Schertl   +29 more
wiley   +1 more source

Rising Connectivity, Shifting Hubs: The Evolving Network and Governance Challenges of Global Wild‐Sourced Trade

Animal Conservation, EarlyView.
Wild‐sourced wildlife trade is not only increasing in volume but also changing in network structure. Using three decades of CITES trade records, we found that the wild‐sourced wildlife trade has become increasingly connected and taxonomically uneven, with Anthozoa contributing a growing share.
Jing Wang, L. Roman Carrasco, Yunrui Ji, Xiuxiang Meng   +3 more
wiley   +1 more source

Surgical management of a penetrating cardiac foreign body causing tamponade in a dog: case report

Australian Veterinary Journal, EarlyView.
Background Penetrating cardiac foreign bodies are rare in dogs but can result in life‐threatening complications, including pericardial effusion and cardiac tamponade. Prompt diagnosis, emergency stabilization, and definitive surgical management are essential to achieve a favorable outcome.
RB Abibe, SC Rahal, GB Mazzali, FJT Neto, VM d V Machado, CVS Brandão   +5 more
wiley   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

BJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Narayan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan   +14 more
wiley   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

Brain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar, Maysa Al‐Hussaini, Vani Santosh, Vaishali Suri, Sung‐Hye Park, Yue‐Shan Piao, Tarik Tihan, Ho‐Keung Ng, Michael Buckland, Rakesh Jalali, Yonehiro Kanemura, Pieter Wesseling, Takashi Komori   +12 more
wiley   +1 more source

Advanced basal cell carcinoma, the hedgehog pathway, and treatment options – role of smoothened inhibitors

, 2015
Leslie A Fecher,1,3 William H Sharfman2 1Department of Internal Medicine and Dermatology, Indiana University Health Simon Cancer Center, Indianapolis, IN, USA; 2The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA ...
Sharfman WH, Fecher LA
core  

Wuguchong Bioactive Peptides Promote Wound Healing via Hedgehog Pathway‑Mediated Fibroblast Modulation. [PDF]

Chem Biodivers
Li K, Sun Y, Pang L, Gao T, Diao Y, Fan S.   +5 more
europepmc   +1 more source

Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival

Brain Pathology, EarlyView.
A practical formalin‐fixed, paraffin‐embedded (FFPE)‐based molecular workflow integrating pathology, immunohistochemistry, and genomic profiling provides clinically meaningful subgroup classification of pediatric medulloblastoma and expands molecular evidence from an underrepresented Central Asian population. Abstract Medulloblastoma is the most common
Aidos Bolatov, Askhat Zhakupov, Aizhan Abdikadirova, Malika Sapargaliyeva, Bakytkali Ibraimov, Zhanat Zhalimbetova, Gabit Ólenbay, Berik Zhetpisbayev, Xingzhi Xu, Mirgul Bayanova   +9 more
wiley   +1 more source