Results 171 to 180 of about 4,715,625 (390)
Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus [PDF]
, 1999 Ge Wang, Boyuan Wang, Jin Jiang
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Scientific Reports, 2018 Autosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by mutation of PKD1 or PKD2, which encode polycystin 1 and 2, respectively. The polycystins localize to primary cilia and the functional loss of the polycystin complex leads to the formation ...
Luciane M. Silva +6 more
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito +9 more
wiley +1 more source
Indian Hedgehog Suppresses a Stromal Cell–Driven Intestinal Immune Response
Cellular and Molecular Gastroenterology and Hepatology, 2018 Upon intestinal epithelial damage a complex wound healing response is initiated to restore epithelial integrity and defend against pathogenic invasion. Epithelium-derived Indian Hedgehog (Ihh) functions as a critical sensor in this process.
B. Florien Westendorp +16 more
doaj +1 more source
Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. [PDF]
, 1996 M. Hammerschmidt +2 more
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Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment
Molecular Cancer, 2016 Cancer poses a serious health problem in society and is increasingly surpassing cardiovascular disease as the leading cause of mortality in the United States.
Ann Hanna, L. Shevde
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa +2 more
wiley +1 more source
The Role of GLI-1 in Endocrine Resistant Breast Cancer [PDF]
, 2014 Estrogen receptor positive (ER+) and estrogen receptor negative (ER-) are two major types of breast cancer. For women with ER+ positive breast cancer, patients are treated with the antiestrogenic compounds, tamoxifen or faslodex for five years ...
Rudolph, Mark
core
Molecular anatomy of emerging Xenopus left–right organizer at successive developmental stages
Developmental Dynamics, EarlyView.Abstract Background Vertebrate left–right symmetry breaking is preceded by formation of left–right organizer. In Amphibian, this structure is formed by gastrocoel roof plate, which emerges from superficial suprablastoporal cells. GRP is subdivided into medial area, which generates leftward flow by rotating monocilia and lateral Nodal1 expressing areas,
Natalia Petri +3 more
wiley +1 more source
Costal2, a Novel Kinesin-Related Protein in the Hedgehog Signaling Pathway [PDF]
, 1997 John C. Sisson +3 more
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