Results 201 to 210 of about 113,623 (349)

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

Cell Proliferation, EarlyView.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang, Miao Yu, Hangbo Liu, Kai Sun, Chenxin Geng, Haochen Liu, Hailan Feng, Yang Liu, Hu Zhao, Dong Han   +9 more
wiley   +1 more source

#10. Investigating the role of non-canonical Hedgehog signaling in paclitaxel-resistant bone- metastatic breast cancer

Jade S. Miller, Julie A. Sterling
openalex   +1 more source

Attenuation of Notch and Hedgehog Signaling Is Required for Fate Specification in the Spinal Cord

, 2012
Peng Huang, Fengzhu Xiong, Sean G. Megason, Alexander F. Schier   +3 more
openalex   +2 more sources

Publisher's Note: Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components

, 2022
Friederike Hantel, Huaize Liu, Lisa Fechtner, Herbert Neuhaus, Jie Ding, Danilo Arlt, Peter Walentek, Pablo Villavicencio‐Lorini, Christoph Gerhardt, Thomas Hollemann, Thorsten Pfirrmann   +10 more
openalex   +2 more sources

IFT139 regulates Hedgehog signaling and cilia structure through ciliary protein localization. [PDF]

Biol Open
Nishat K, Klug Z, Faimma Mia J, Stump SM, Cherry Liu Y.   +4 more
europepmc   +1 more source

Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways

Cell Proliferation, EarlyView.
IL10_ApoEVs, generated during IL‐10‐induced fibroblast apoptosis, reprogram fibroblast metabolism and inhibit fibrosis to promote scarless skin healing. By enhancing mitochondrial OXPHOS, suppressing glycolysis, and downregulating Hedgehog signaling, IL10_ApoEVs shift collagen deposition toward regenerative type III collagen, offering a novel strategy ...
Yang Zou, Jinglun Zhang, Wenxuan Mao, Shuting Jiang, Cheng Xu, Jiayi Meng, Heng Dong, Yongbin Mou   +7 more
wiley   +1 more source

Hedgehog/GLI signaling in tumor immunity - new therapeutic opportunities and clinical implications [PDF]

, 2019
Sandra Grund‐Gröschke, Georg Stockmaier, Fritz Aberger   +2 more
openalex   +1 more source

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression. [PDF]

Front Cell Dev Biol
Baidya S, Barua U, Shanto MR, Sonia TS, Amin MA, Sultana S, Jerin N, Jahan K, Jahan I, Ahmed S, Moinul Islam M, Parial R, Hossain MM, Noman ASM.   +13 more
europepmc   +1 more source

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

Evolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers, Alleigh Amaismeier, Kathryn Thiel, William Anyonge, Suzanne E. McGaugh, Tyler E. Boggs, Clifford J. Tabin, Joshua B. Gross   +7 more
wiley   +1 more source

β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells [PDF]

, 2017
Evelina Miele, Agnese Pò, Federica Begalli, Laura Antonucci, Angela Mastronuzzi, Carlo Efisio Marras, Andrea Carai, Danilo Cucchi, Luana Abballe, Zein Mersini Besharat, Giuseppina Catanzaro, Paola Infante, Lucia Di Marcotullio, Gianluca Canettieri, Enrico De Smaele, Isabella Screpanti, Franco Locatelli, Elisabetta Ferretti   +17 more
openalex   +1 more source