Results 251 to 260 of about 4,715,625 (390)

The kinase PLK1 promotes Hedgehog signaling-dependent resistance to the antiandrogen enzalutamide in metastatic prostate cancer. [PDF]

Sci Signal
Zhang Q, Peng J, Zhang Y, Liu J, He D, Zhao Y, Wang X, Li C, Kong Y, Wang R, Mao F, Wang C, Wang Q, Zhang M, Wang J, Yang HS, Liu X.   +16 more
europepmc   +1 more source

Conserved expression control and shared activity between cognate T‐box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development [PDF]

, 2002
Yuka Takabatake, Takashi Takabatake, Satoru Sasagawa, Kazuhito Takeshima   +3 more
openalex   +1 more source

The long and short of hedgehog signaling

Cell, 1995
Clifford J. Tabin, Randy L. Johnson
openaire   +3 more sources

Rapid and Effective Neuronal Conversion of Human Glioblastoma In Vitro and In Vivo Using Potent Small Molecules

Cell Proliferation, EarlyView.
A potent combination of small molecules YFSS (Y27632, Forskolin, SB431542, SP600125) that were screened through a neuronal‐specific promoter–reporter system TUBB3::mCherry effectively induces neuronal‐GBM conversion in vitro and in vivo, unveiling molecular mechanisms that offer a theoretical basis and a potential therapeutic strategy for treating GBM.
Ya'nan Hu, Jinming Liu, Jian Tu, Min Yang, Qisheng He, Fei Li, Xiaojing Xu, Zhongqing Ji, Jianwei Xu, Wentao Zhong, Mengwen Yan, Ying Yang, Huanxiang Zhang   +12 more
wiley   +1 more source

Hedgehog Signaling Pathway in Fibrosis and Targeted Therapies. [PDF]

Biomolecules
Hu Y, Peng L, Zhuo X, Yang C, Zhang Y.
europepmc   +1 more source

Hedgehog Signalling: Pulling Apart Patched and Smoothened [PDF]

, 2002
D. Stark
openalex   +1 more source

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

Cell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang, Farhad Soheilmoghaddam, Peter Pivonka, Joan Li, Samuel Rudd, Trifanny Yeo, Ji Tu, Yibo Zhu, Justin J. Cooper‐White   +8 more
wiley   +1 more source

<i>TULP3</i> Regulates Proliferation and Differentiation of 3T3-L1 Preadipocytes Through the Hedgehog Signaling Pathway. [PDF]

Biology (Basel)
Jin X, Zhang Y, Wang Y, Cao H, Song Q, Huang J, Chen W, Tang H, Zeng Y.   +8 more
europepmc   +1 more source

Ptc1 and Ptc2 Transcripts Provide Distinct Readouts of Hedgehog Signaling Activity during Chick Embryogenesis

, 2001
Richard V. Pearse, Kyle Vogan, Clifford J. Tabin   +2 more
openalex   +1 more source

GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer

Cell Proliferation, EarlyView.
GANT61 induced autophagy via the AKT pathway and promoted the accumulation of lipid droplets in both cell lines. The molecular mechanism behind this lipid accumulation appears to involve the mediation of SREBP1. Furthermore, the combination of GANT61 with CQ/Fatostatin significantly inhibited the proliferation and clonogenicity of SKOV3 and SKOV3PTX ...
Yibin Pan, Lingfeng Chen, Jinlu Shen, Shihao Hong, Xiaojing Guan, Xudong Ma, Rongrong Tang, Meifei Lu, Fangying Sun, Shanliang Shang, Yongdong Dai, Zhaokai Zhou, Songying Zhang, Jianhua Yang   +13 more
wiley   +1 more source