Advanced Science, EarlyView.A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee +8 more
wiley +1 more source
Advanced Science, EarlyView.This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu +12 more
wiley +1 more source
Ectoparasitic infestations of the European hedgehog (Erinaceus europaeus) in Urmia city, Iran: First report [PDF]
Veterinary Research Forum, 2013 Hedgehogs are small, nocturnal mammals that become popular in the world and have significant role in transmission of zoonotic agents. Some of the agents are transmitted by ticks and fleas such as rickettsial agents.
Tahmineh Gorgani-Firouzjaee +3 more
doaj
An Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signalling without loss or malformation of cilia [PDF]
, 2011 Suzanne Rix +3 more
openalex +1 more source
Hematology, Biochemistry, and Protein Electrophoresis Reference Intervals of Western European Hedgehog (Erinaceus europaeus) from a Rehabilitation Center in Northern Portugal [PDF]
, 2023 Sofia Rosa +4 more
openalex +1 more source
Crater Observing Bioinspired Rolling Articulator (COBRA)
Advanced Intelligent Systems, EarlyView.Crater Observing Bio‐inspired Rolling Articulator (COBRA) is a modular, snake‐inspired robot that addresses the mobility challenges of extraterrestrial exploration sites such as Shackleton Crater. Incorporating snake‐like gaits and tumbling locomotion, COBRA navigates both uneven surfaces and steep crater walls.
Adarsh Salagame +4 more
wiley +1 more source
Genetic Activation of Hedgehog Signaling Unbalances the Rate of Neural Stem Cell Renewal by Increasing Symmetric Divisions [PDF]
, 2014 Julien Ferent +6 more
openalex +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani +17 more
wiley +1 more source
Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
, 2023 Sun‐Hee Hwang +4 more
openalex +1 more source
Disparity of turbinal bones in placental mammals
The Anatomical Record, EarlyView.Abstract Turbinals are key bony elements of the mammalian nasal cavity, involved in heat and moisture conservation as well as olfaction. While turbinals are well known in some groups, their diversity is poorly understood at the scale of placental mammals, which span 21 orders.
Quentin Martinez +11 more
wiley +1 more source