Results 41 to 50 of about 191,259 (287)
A two-state model for helicase translocation and unwinding of nucleic acids [PDF]
, 2008 Helicases are molecular motors that unwind double-stranded nucleic acids (dsNA), such as DNA and RNA). Typically a helicase translocates along one of the NA single strands while unwinding and uses adenosine triphosphate (ATP) hydrolysis as an energy ...
Ashok Garai +7 more
core +2 more sources
The RNA helicase database [PDF]
Nucleic Acids Research, 2010 RNA helicases are ubiquitous and essential enzymes that function in nearly all aspects of RNA metabolism. The RNA helicase database (www.rnahelicase.org) integrates the wealth of accumulating information on RNA helicases in a readily accessible format.
Anja Jankowsky +2 more
openaire +3 more sources
eLife, 2016 Replisome assembly requires the loading of replicative hexameric helicases onto origins by AAA+ ATPases. How loader activity is appropriately controlled remains unclear.
Iris V Hood, James M Berger
doaj +1 more source
Identification of Five Putative Yeast RNA Helicase Genes [PDF]
, 1990 The RNA helicase gene family encodes a group of eight homologous proteins that share regions of sequence similarity. This group of evolutionarily conserved proteins presumably all utilize ATP (or some other nucleoside triphosphate) as an energy source ...
Abelson, John +2 more
core +1 more source
Biochemical characterization of Plasmodium falciparum parasite specific helicase 1 (PfPSH1)
FEBS Open Bio, 2019 Malaria, a disease caused by infection with parasites of the genus Plasmodium, causes millions of deaths worldwide annually. Of the five Plasmodium species that can infect humans, Plasmodium falciparum causes the most serious parasitic infection.
Manish Chauhan +4 more
doaj +1 more source
EMBO Journal, 2019 Aberrant transcription‐associated RNA:DNA hybrid (R‐loop) formation often causes catastrophic conflicts during replication, resulting in DNA double‐strand breaks and genomic instability.
Sofiane Y Mersaoui +6 more
semanticscholar +1 more source
Helicase activity on DNA as a propagating front [PDF]
, 2003 We develop a propagating front analysis, in terms of a local probability of zipping, for the helicase activity of opening up a double stranded DNA (dsDNA).
Alberts B. +5 more
core +2 more sources
Cold Spring Harbor Symposia on Quantitative Biology, 1979 In summary, we postulate that DNA unwinding and ATP dephosphorylation are coupled in different ways, depending on whether the fibrous ATPase or one of the globular ATPases provides the catalytic agent. Unanswered is the question of whether there is stoichiometry of ATP utilization during the unwinding of a duplex, and unsolved is the role of the ...
B, Kuhn +2 more
openaire +2 more sources
Helicase on DNA: A Phase coexistence based mechanism [PDF]
, 2003 We propose a phase coexistence based mechanism for activity of helicases, ubiquitous enzymes that unwind double stranded DNA. The helicase-DNA complex constitutes a fixed-stretch ensemble that entails a coexistence of domains of zipped and unzipped ...
Amundsen S K +16 more
core +3 more sources
Frontiers in Microbiology, 2018 Chromosomal replication initiation requires dynamic mechanisms in higher-order nucleoprotein complexes that are constructed at the origin of replication.
Yukari Sakiyama +5 more
doaj +1 more source