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HELIOS-Expressing Human CD8 T Cells Exhibit Limited Effector Functions
Frontiers in Immunology, 2023 IntroductionThe transcription factor HELIOS is primarily known for its expression in CD4 regulatory T cells, both in humans and mice. In mice, HELIOS is found in exhausted CD8 T cells.
Pierre van der Bruggen +2 more
exaly +4 more sources
Phenotypic and functional properties of Helios+ regulatory T cells. [PDF]
PLoS ONE, 2012 Helios, an Ikaros family transcription factor, is preferentially expressed at the mRNA and protein level in regulatory T cells. Helios expression previously appeared to be restricted to thymic-derived Treg.
Daniel J Zabransky +8 more
doaj +2 more sources
Frontiers in Immunology, 2021 CD4 Tregs are involved in the regulation of various autoimmune diseases but believed to be highly heterogeneous. Studies have indicated that Helios controls a distinct subset of functional Tregs.
Tao Yang, Kuanfeng Xu, Xinyu Xu
exaly +3 more sources
Difference between CD25+Tregs and Helios+Tregs in a murine model of allergic rhinitis
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: Regulatory T or Treg cells, balance the peripheral immune response to allergens in allergic rhinitis. Traditionally, Treg (CD25+ Treg) is identified by the coexpression of Foxp3 and CD25, but this strategy does not represent the true ...
Yun-Xiu Wang, Zhao-Wei Gu, Zhi-Wei Cao
doaj +1 more source
En el recinto común dedicado a Apolo y Helios (Platón, Lg., 945 b-948 b)
Nova Tellus, 2021 En Leyes, 945 b-948 b, Platón introduce la figura de los eúthӯnoi o “correctores” y los relaciona directamente con el culto común de Helios y Apolo. Sostengo que, al hacer esto, el filósofo ha pretendido conectar la República y las Leyes en torno a la ...
Miguel Ángel Spinassi
doaj +1 more source
Gephyra, 2020 Four new epigraphic finds from the Mihalıççık District encourage us to reconsider the role that villages and associations played among those who made dedications to the divine pair Hosios kai Dikaios.
Altay COŞKUN
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Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells
Frontiers in Immunology, 2021 BackgroundAdiponectin is an important immunomodulatory mediator in inflammatory conditions. While we previously showed that adiponectin receptor 1 (AdipoR1) is expressed in murine regulatory T cells (Tregs), its expression in human Tregs remain unknown ...
Patricia Ramos-Ramírez +5 more
doaj +1 more source
Helio- and asteroseismology [PDF]
Proceedings of the International Astronomical Union, 2001 AbstractObservations of solar and stellar oscillations are providing detailed information about stellar interiors. In the case of the Sun the set of observed frequencies is sufficiently detailed and accurate that the properties of the solar interior, such as sound speed, density and internal rotation, can be inferred with substantial precision and ...
openaire +4 more sources
BMC Cancer, 2022 There are different subsets of T regulatory cells (Tregs), orchestrating critical roles in the regulation of anti-tumor immunity in colorectal cancer (CRC).
Mohammad A. Al-Mterin +4 more
doaj +1 more source
Vaccines, 2022 T regulatory cells (Tregs) play different roles in the regulation of anti-tumor immunity in colorectal cancer (CRC), depending on the presence of different Treg subsets.
Mohammad A. Al-Mterin +2 more
doaj +1 more source