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Immune Checkpoints in Viral Infections [PDF]
Viruses, 2020 As evidence has mounted that virus-infected cells, such as cancer cells, negatively regulate the function of T-cells via immune checkpoints, it has become increasingly clear that viral infections similarly exploit immune checkpoints as an immune system ...
Huiming Cai +11 more
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The Glycosylation of Immune Checkpoints and Their Applications in Oncology
Pharmaceuticals, 2022 Tumor therapies have entered the immunotherapy era. Immune checkpoint inhibitors have achieved tremendous success, with some patients achieving long-term tumor control.
Linlin Zheng +10 more
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Immune checkpoints: cross-disease insights and clinical dilemmas [PDF]
Biomarker ResearchThe immune checkpoints and their inhibitors are revolutionary advances in tumour immunotherapy. Immune checkpoints, however, have a broad spectrum effect.
Yue Shu +7 more
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Regulation of immune checkpoints by electronic cigarette [PDF]
Frontiers in OncologyAn e-cigarette device consists of a cartridge that stores e-liquid, a mouthpiece, a heating element, and a power source. The e-liquid is heated by a coil and a wick, generating an aerosol that is inhaled by the user.
Ana Gabriela Leija-Montoya +7 more
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Irinotecan Modulates Immune Checkpoints in Neuroblastoma [PDF]
ImmunoTargets and TherapyTom Lapidus,1 Elina Zorde-Khvalevsky,1 Alaa Jolani,1 Gal Goldstein,2 Amnon Peled1 1Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; 2The Pediatric Hemato-Oncology Department, Hadassah- Hebrew ...
Lapidus T +4 more
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Current Progress and Future Perspectives of Immune Checkpoint in Cancer and Infectious Diseases
Frontiers in Genetics, 2021 The inhibitory regulators, known as immune checkpoints, prevent overreaction of the immune system, avoid normal tissue damage, and maintain immune homeostasis during the antimicrobial or antiviral immune response.
Xin Cai +6 more
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Clinical Research on the Mechanisms Underlying Immune Checkpoints and Tumor Metastasis
Frontiers in Oncology, 2021 This study highlights aspects of the latest clinical research conducted on the relationship between immune checkpoints and tumor metastasis. The overview of each immune checkpoint is divided into the following three sections: 1) structure and expression;
Xi-Yang Tang +7 more
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Emerging phagocytosis checkpoints in cancer immunotherapy
Signal Transduction and Targeted Therapy, 2023 Cancer immunotherapy, mainly including immune checkpoints-targeted therapy and the adoptive transfer of engineered immune cells, has revolutionized the oncology landscape as it utilizes patients’ own immune systems in combating the cancer cells.
Yu’e Liu +9 more
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Acta Pharmaceutica Sinica B, 2021 Immune checkpoints are the crucial regulators of immune system and play essential roles in maintaining self-tolerance, preventing autoimmune responses, and minimizing tissue damage by regulating the duration and intensity of the immune response ...
Yuli Wang +10 more
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Immune checkpoint inhibitors for multiple myeloma immunotherapy
Experimental Hematology & Oncology, 2023 Multiple myeloma (MM) is related to immune disorders, recent studys have revealed that immunotherapy can greatly benefit MM patients. Immune checkpoints can negatively modulate the immune system and are closely associated with immune escape.
Zhaoyun Liu +5 more
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