Regulation of immune checkpoints by electronic cigarette [PDF]
Frontiers in OncologyAn e-cigarette device consists of a cartridge that stores e-liquid, a mouthpiece, a heating element, and a power source. The e-liquid is heated by a coil and a wick, generating an aerosol that is inhaled by the user.
Ana Gabriela Leija-Montoya +7 more
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The Glycosylation of Immune Checkpoints and Their Applications in Oncology
Pharmaceuticals, 2022 Tumor therapies have entered the immunotherapy era. Immune checkpoint inhibitors have achieved tremendous success, with some patients achieving long-term tumor control.
Chenhui Cao, Xu Chuan
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Immune checkpoints in immune response to glioma: two sides of the same coin [PDF]
Frontiers in ImmunologyGliomas are aggressive brain tumors of glial origin accounting for about 80% of the central nervous system (CNS) malignancies. Glioma cells are known to form a highly immunosuppressive tumor microenvironment (TME) capable of inhibiting T cell activation ...
Oxana Musatova +4 more
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Harnessing the immune system by targeting immune checkpoints: Providing new hope for Oncotherapy
Frontiers in Immunology, 2022 With the goal of harnessing the host’s immune system to provide long-lasting remission and cures for various cancers, the advent of immunotherapy revolutionized the cancer therapy field.
Qiao Zhou, Zhou Qiao
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Functional interaction between immune checkpoints and lipid metabolism in the development of arteriosclerosis obliterans [PDF]
Frontiers in ImmunologyArteriosclerosis obliterans (ASO) is a chronic vascular disease characterized by narrowing or occlusion of the vascular lumen. Its pathogenesis is complex and closely associated with lipid metabolism disorders and chronic inflammation.
Junyi Zhang +14 more
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Irinotecan Modulates Immune Checkpoints in Neuroblastoma [PDF]
ImmunoTargets and TherapyTom Lapidus,1 Elina Zorde-Khvalevsky,1 Alaa Jolani,1 Gal Goldstein,2 Amnon Peled1 1Goldyne Savad Institute of Gene Therapy, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; 2The Pediatric Hemato-Oncology Department, Hadassah- Hebrew ...
Lapidus T +4 more
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The Latest Look at PDT and Immune Checkpoints
Current Issues in Molecular BiologyPhotodynamic therapy (PDT) can not only directly eliminate cancer cells, but can also stimulate antitumor immune responses. It also affects the expression of immune checkpoints. The purpose of this review is to collect, analyze, and summarize recent news
David Aebisher +2 more
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Post-translational modifications of cancer immune checkpoints: mechanisms and therapeutic strategies [PDF]
Molecular CancerImmunotherapies, particularly immune checkpoint inhibitors (ICIs), have revolutionized cancer clinical management, but low response rates and treatment resistance remain challenging.
Haiqing Jia +9 more
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Current Progress and Future Perspectives of Immune Checkpoint in Cancer and Infectious Diseases
Frontiers in Genetics, 2021 The inhibitory regulators, known as immune checkpoints, prevent overreaction of the immune system, avoid normal tissue damage, and maintain immune homeostasis during the antimicrobial or antiviral immune response.
Xin Cai +6 more
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Clinical Research on the Mechanisms Underlying Immune Checkpoints and Tumor Metastasis
Frontiers in Oncology, 2021 This study highlights aspects of the latest clinical research conducted on the relationship between immune checkpoints and tumor metastasis. The overview of each immune checkpoint is divided into the following three sections: 1) structure and expression;
Xi-Yang Tang +7 more
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