Results 11 to 20 of about 1,252,407 (298)
Soluble immune checkpoints in cancer: production, function and biological significance
Journal for ImmunoTherapy of Cancer, 2018 Immune checkpoints play important roles in immune regulation, and blocking immune checkpoints on the cell membrane is a promising strategy in the treatment of cancer.
Daqian Gu +4 more
doaj +2 more sources
CANCER IMMUNOTHERAPY BASED ON THE BLOCKADE OF IMMUNE CHECKPOINTS [PDF]
Медицинская иммунология, 2015 Immune checkpoints represent the system of inhibitory mechanisms regulating the activation of the immune response, preventing the autoimmune processes and modulating the immune response by decreasing the immune cell-mediated damage of tissues and organs.
A. V. Bogolyubova +3 more
doaj +2 more sources
The Iraqi Journal of Medical SciencesBackground: The Corona virus disease 2019 (COVID-19) is a complicated respiratory syndrome caused by novel Corona virus that spread swiftly throughout the world.
Selda Ezzaldeen +2 more
doaj +2 more sources
The Latest Look at PDT and Immune Checkpoints
Current Issues in Molecular BiologyPhotodynamic therapy (PDT) can not only directly eliminate cancer cells, but can also stimulate antitumor immune responses. It also affects the expression of immune checkpoints. The purpose of this review is to collect, analyze, and summarize recent news
David Aebisher +2 more
doaj +2 more sources
Immune Checkpoints Mediate Tumor Immune Regulation through Metabolic Pathways
Chinese Journal of Lung CancerImmune checkpoints include a series of receptor-ligand pairs that play a key role in the proliferation, activation, and immune regulatory responses of immune cells.
Weiguang DU +6 more
doaj +2 more sources
Immune checkpoint inhibitors [PDF]
Journal of Experimental Medicine, 2021 Three papers by James Allison and Tasuku Honjo published in JEM between 1995 and 2000 crystallized seminal insights into the role of CTLA-4 and PD-1 in immunosuppression (Krummel and Allison. 1995. J. Exp. Med.https://doi.org/10.1084/jem.182.2.459; van Elsas et al. 1999. J. Exp. Med.https://doi.org/10.1084/jem.190.3.355; Freeman et al. 2000. J.
Kroemer, Guido, Zitvogel, Laurence
openaire +3 more sources
Immune Checkpoint Inhibitors and the Heart [PDF]
Frontiers in Cardiovascular Medicine, 2021 Immune checkpoint inhibitors (ICIs) represent a break-through treatment for a large number of cancer types. This treatment is increasingly being recommended. ICIs are prescribed for primary tumours and for metastases, adjuvant/neo-adjuvant therapy.
Diana Larisa Mocan-Hognogi +11 more
openaire +3 more sources
Immune Checkpoints in Leukaemia as Gatekeepers of Immuno-Modulation. [PDF]
Immunology\ua9 2026 John Wiley & Sons Ltd.Immune evasion remains one of the key hallmarks in cancer survival by which tumours avoid immune system response.
Ramesh J +10 more
europepmc +5 more sources
Configuring Therapeutic Aspects of Immune Checkpoints in Lung Cancer [PDF]
, 2023 Immune checkpoints are unique components of the body’s defense mechanism that safeguard the body from immune responses that are potent enough to harm healthy body cells.
Apostolopoulos, Vasso +11 more
core +1 more source
Immune checkpoints and cancer immunotherapies: insights into newly potential receptors and ligands [PDF]
, 2023 Checkpoint markers and immune checkpoint inhibitors have been increasingly identified and developed as potential immunotherapeutic targets in various human cancers.
Haleh Hamedifar +9 more
core +1 more source