Results 31 to 40 of about 1,252,407 (298)

Cancer therapeutic implications of microRNAs in the regulation of immune checkpoint blockade [PDF]

ExRNA, 2019
Dampening of patients’ immune response to tumor-specific antigens is a major reason for tumor development and progression. Within tumor microenvironment, aberrant expression of immune checkpoints changes T lymphocyte activity, and induces immune ...
Yan Zhang, Toshihiko Tanno, Chrysi Kanellopoulou   +2 more
doaj   +1 more source

Table_10_Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction.xlsx

, 2022
Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of monoclonal B lymphocytes in peripheral blood, even in early stages [monoclonal B-cell ...
Juanes-Velasco, Pablo, Lécrevisse, Quentin, Fuentes, Manuel, Carlos Eduardo Pedreira (8497368), González, Marcos, Marcos González (120382), Landeira-Viñuela, Alicia, Laura Díaz-Muñoz (13873298), Hernández, Ángela-Patricia, Orfao, Alberto, Díaz-Muñoz, Laura, Arias-Hidalgo, Carlota, Marina L. García-Vaquero (12010898), Quentin Lecrevisse (8041148), Almudena Navarro-Bailón (11808457), Alcoceba, Miguel, Miguel Alcoceba (3805117), Rafael Góngora (10498154), Pedreira, C. E., Pablo Juanes-Velasco (10498160), Alberto Orfao (108164), Manuel Fuentes (143757), Ángela-Patricia Hernández (12010907), José Manuel Sánchez-Santos (13873301), García-Vaquero, Marina L., Alicia Landeira-Viñuela (10498157), Carlota Arias-Hidalgo (13873295), Javier De Las Rivas (19407), De Las Rivas, Javier, Navarro-Bailón, Almudena, Góngora, Rafael, Sánchez-Santos, José Manuel   +31 more
core   +1 more source

Table_11_Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction.xlsx

, 2022
Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of monoclonal B lymphocytes in peripheral blood, even in early stages [monoclonal B-cell ...
Juanes-Velasco, Pablo, Lécrevisse, Quentin, Fuentes, Manuel, Carlos Eduardo Pedreira (8497368), González, Marcos, Marcos González (120382), Landeira-Viñuela, Alicia, Laura Díaz-Muñoz (13873298), Hernández, Ángela-Patricia, Orfao, Alberto, Díaz-Muñoz, Laura, Arias-Hidalgo, Carlota, Marina L. García-Vaquero (12010898), Quentin Lecrevisse (8041148), Almudena Navarro-Bailón (11808457), Alcoceba, Miguel, Miguel Alcoceba (3805117), Rafael Góngora (10498154), Pedreira, C. E., Pablo Juanes-Velasco (10498160), Alberto Orfao (108164), Manuel Fuentes (143757), Ángela-Patricia Hernández (12010907), José Manuel Sánchez-Santos (13873301), García-Vaquero, Marina L., Alicia Landeira-Viñuela (10498157), Carlota Arias-Hidalgo (13873295), Javier De Las Rivas (19407), De Las Rivas, Javier, Navarro-Bailón, Almudena, Góngora, Rafael, Sánchez-Santos, José Manuel   +31 more
core   +1 more source

Myocarditis with Immune Checkpoint Blockade [PDF]

New England Journal of Medicine, 2017
In their discussion of fulminant myocarditis and complete heart block during immune checkpoint therapy, Johnson et al. do not discuss the possible role of circulating anticonductive tissue autoantibodies (ACTA) in the pathogenesis of the sudden heart block and myocarditis.1 Since it is not known which autoantigens (other than troponin I, which was ...
Javid J, Moslehi, Douglas B, Johnson, Jeffrey A, Sosman   +2 more
openaire   +5 more sources

2016 Jeffrey M. Hoeg Award Lecture: Immune Checkpoints in Atherosclerosis: Toward Immunotherapy for Atheroprotection [PDF]

, 2018
Innate and adaptive immune effector mechanisms, in conjunction with hyperlipidemia, are important drivers of atherosclerosis. The interaction between the different immune cells and the secretion of cytokines and chemokines determine the progression of ...
Rouwet, Ellen, Lutgens, Esther, Lutgens, E   +2 more
core   +1 more source

Table_7_Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction.xlsx

, 2022
Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of monoclonal B lymphocytes in peripheral blood, even in early stages [monoclonal B-cell ...
Juanes-Velasco, Pablo, Lécrevisse, Quentin, Fuentes, Manuel, Carlos Eduardo Pedreira (8497368), González, Marcos, Marcos González (120382), Landeira-Viñuela, Alicia, Laura Díaz-Muñoz (13873298), Hernández, Ángela-Patricia, Orfao, Alberto, Díaz-Muñoz, Laura, Arias-Hidalgo, Carlota, Marina L. García-Vaquero (12010898), Quentin Lecrevisse (8041148), Almudena Navarro-Bailón (11808457), Alcoceba, Miguel, Miguel Alcoceba (3805117), Rafael Góngora (10498154), Pedreira, C. E., Pablo Juanes-Velasco (10498160), Alberto Orfao (108164), Manuel Fuentes (143757), Ángela-Patricia Hernández (12010907), José Manuel Sánchez-Santos (13873301), García-Vaquero, Marina L., Alicia Landeira-Viñuela (10498157), Carlota Arias-Hidalgo (13873295), Javier De Las Rivas (19407), De Las Rivas, Javier, Navarro-Bailón, Almudena, Góngora, Rafael, Sánchez-Santos, José Manuel   +31 more
core   +1 more source

Cancer Immunotherapy by Blocking Immune Checkpoints on Innate Lymphocytes [PDF]

, 2020
Immune checkpoints refer to a plethora of inhibitory pathways of the immune system that play a crucial role in maintaining self-tolerance and in tuning the duration and amplitude of physiological immune responses to minimize collateral tissue damages ...
Calvi, Michela, Camilla Jandus, Emanuela Marcenaro, Jandus, C., Calvi M., Obino, V., Greppi, M., Valentina Obino, Bozzo, Matteo, Lemoli R. M., Simona Candiani, Trabanelli S., Matteo Bozzo, Michela Calvi, Zaghi E., Lemoli, R.M., Minetto P., Lemoli, Roberto Massimo, Fabio Guolo, Zaghi, E., Mavilio, D., Guolo, Fabio, Pesce, Silvia, Candiani, S., Mavilio, Domenico, Jandus C., Marcenaro, Emanuela, Guolo, F., Pesce, S., Trabanelli, Sara, Obino, Valentina, Roberto Massimo Lemoli, Calvi, M., Jandus, Camilla, Sara Trabanelli, Bozzo M., Zaghi, Elisa, Domenico Mavilio, Bozzo, M., Paola Minetto, Candiani S., Di Vito, C., Obino V., Candiani, Simona, Minetto, Paola, Greppi, Marco, Mavilio D., Clara Di Vito, Marcenaro E., Greppi M., Guolo F., Marcenaro, E., Elisa Zaghi, Pesce S., Trabanelli, S., Marco Greppi, Di Vito, Clara, Silvia Pesce, Di Vito C., Minetto, P., Di Vito C, Lemoli RM, Minetto P, Trabanelli S, Zaghi E, Marcenaro E, Calvi M, Jandus C, Obino V, Guolo F, Pesce S, Greppi M, Candiani S, Mavilio D, Bozzo M   +74 more
core   +1 more source

Immune Checkpoint Inhibitors and Neurotoxicity

Current Neuropharmacology, 2021
: Immune checkpoint inhibitors (ICIs) have recently been used as a promising treatment for cancer, while their toxicity and immune-related side effects can be seen in any organ, including the nervous system. In contrast to other immune-related adverse events (irAEs), neurological irAEs (nAEs) are rare, with ...
Zhao, Zhiyi, Zhang, Chunlin, Zhou, Lian, Dong, Pan, Shi, Lei   +4 more
openaire   +3 more sources

Varied functions of immune checkpoints during cancer metastasis

, 2020
Immune checkpoints comprise diverse receptors and ligands including costimulatory and inhibitory molecules, which play monumental roles in regulating the immune system. Immune checkpoints retain key potentials in maintaining the immune system homeostasis
Safarzadeh A., Falavand Jozaaee R., Argentiero A., Alizadeh M., Hajiasgharzadeh K., Derakhshani A., Baradaran B., Beyranvand F., Silvestris N., Baghbanzadeh A., Khalil Hajiasgharzadeh, Afshin Derakhshani, Mohsen Alizadeh, Amir Baghbanzadeh, Antonella Argentiero, Ali Safarzadeh, Behzad Baradaran, Nicola Silvestris, Reza Falavand Jozaaee, Fatemeh Beyranvand   +19 more
core   +1 more source

Dynamics of Immune Checkpoints, Immune System, and BCG in the Treatment of Superficial Bladder Cancer [PDF]

, 2017
This paper aims to study the dynamics of immune suppressors/checkpoints, immune system, and BCG in the treatment of superficial bladder cancer. Programmed cell death protein-1 (PD-1), cytotoxic T-lymphocyte-associated antigen 4 (CTLA4), and transforming ...
Farouk Tijjani Saad, Evren Hincal, Bilgen Kaymakamzade   +2 more
core   +1 more source