Results 21 to 30 of about 1,252,407 (298)

Table_5_Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction.xlsx [PDF]

, 2022
Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of monoclonal B lymphocytes in peripheral blood, even in early stages [monoclonal B-cell ...
Navarro Bailón, Almudena, Lecrevisse, Quentin, Juanes-Velasco, Pablo, Fuentes, Manuel, Carlos Eduardo Pedreira (8497368), González, Marcos, Marcos González (120382), Góngora Fernández, Rafael, Landeira-Viñuela, Alicia, Laura Díaz-Muñoz (13873298), Fuentes García, Manuel, Hernández García, Ángela Patricia, Hernández, Ángela-Patricia, Alcoceba Sánchez, Miguel, Orfao, Alberto, Díaz-Muñoz, Laura, Arias-Hidalgo, Carlota, Marina L. García-Vaquero (12010898), Díaz Muñoz, Laura, Orfao de Matos Correia e Vale, José Alberto, Quentin Lecrevisse (8041148), Almudena Navarro-Bailón (11808457), Alcoceba, Miguel, Miguel Alcoceba (3805117), Rafael Góngora (10498154), Pedreira, C. E., Pablo Juanes-Velasco (10498160), Alberto Orfao (108164), Manuel Fuentes (143757), Ángela-Patricia Hernández (12010907), José Manuel Sánchez-Santos (13873301), García-Vaquero, Marina L., Alicia Landeira-Viñuela (10498157), Carlota Arias-Hidalgo (13873295), Sánchez-Santos, José Manuel, Javier De Las Rivas (19407), Pedreira, Carlos Eduardo, De Las Rivas, Javier, Sánchez Santos, José Manuel, Navarro-Bailón, Almudena, Góngora, Rafael, Rivas Sanz, Javier de las   +41 more
core   +1 more source

Cytokines and immune checkpoints trends by article.

, 2023
Cytokines and immune checkpoints trends by article.
María Alejandra Villota-Álava (15368651), Nicolás Lalinde-Ruíz (15368648), Ivon Johanna Rodríguez-Rodríguez (15368654), Laura Camila Martínez-Enriquez (15368639), Carlos Alberto Parra-López (14599806), Esteban Alejandro Velandia-Vargas (15368645), María del Pilar Montilla-Velásquez (15368657), Manuela Llano-León (14599800), Oscar Mauricio Rodríguez-Bohórquez (15368642)   +8 more
core   +1 more source

Immune checkpoints in lung cancer. [PDF]

Breathe (Sheff)
The advent of immune checkpoint inhibitors (ICIs) has revolutionised the management of lung cancer, transforming it from a historically immune-resistant malignancy into a paradigm for durable immunotherapy response. This review provides a comprehensive overview of the biological and clinical foundations of checkpoint regulation in the lung and their ...
Garrido-Martín EM, Kontic M, Rooney C, Mansouri N.   +3 more
europepmc   +4 more sources

Immune checkpoint inhibitors in malignancy [PDF]

Australian Prescriber, 2019
Immune checkpoints normally stop the body from mounting an immune response against healthy cells. Some cancers can acquire these checkpoints so that the tumour cells are not recognised by the immune systemInhibiting the checkpoints therefore enables the tumour cells to be recognised and allows an immune response to be activated against themImmune ...
Luke, Ardolino, Anthony, Joshua
openaire   +2 more sources

Archetypes of checkpoint-responsive immunity

Trends in Immunology, 2021
Responsiveness to immune checkpoint blockade (ICB) therapy in cancer is currently predicted by disparate individual measures - with varying degrees of accuracy - including tumor mutation burden, tumor-infiltrating T cell densities, dendritic cell frequencies, and the expression of checkpoint ligands.
Kwok, Im, Alexis J, Combes, Matthew H, Spitzer, Ansuman T, Satpathy, Matthew F, Krummel   +4 more
openaire   +3 more sources

Immune checkpoint inhibitors [PDF]

Journal of Cell Biology, 2019
Hui details the cell biology underlying the action of immune checkpoint inhibitors.
openaire   +4 more sources

Harnessing the immune system by targeting immune checkpoints: Providing new hope for Oncotherapy

Frontiers in Immunology, 2022
With the goal of harnessing the host’s immune system to provide long-lasting remission and cures for various cancers, the advent of immunotherapy revolutionized the cancer therapy field.
Lu Yu, Minghan Sun, Qi Zhang, Qiao Zhou, Qiao Zhou, Qiao Zhou, Yi Wang   +6 more
doaj   +1 more source

NK Cell-Based Immune Checkpoint Inhibition

Frontiers in Immunology, 2020
Immunotherapy, with an increasing number of therapeutic dimensions, is becoming an important mode of treatment for cancer patients. The inhibition of immune checkpoints, which are the source of immune escape for various cancers, is one such ...
Muhammad Khan, Sumbal Arooj, Hua Wang
doaj   +1 more source

The Role of Immune Checkpoints in Cancer Progression [PDF]

, 2022
Immune checkpoint proteins are like two-faced swords that first act as gatekeepers of the immune system to protect the host from tissue damage. In contrast, these proteins can corroborate cancer progression by inhibiting tumor-specific immune responses.
Prasetya, Rahmad Aji, Wulansari, Devyani Diah   +1 more
core   +2 more sources

Identification of lung adenocarcinoma subtypes and predictive signature for prognosis, immune features, and immunotherapy based on immune checkpoint genes

Frontiers in Cell and Developmental Biology, 2023
Background: Lung adenocarcinoma (LUAD) is the most common variant of non–small cell lung cancer (NSCLC) across the world. Recently, the rapid development of immunotherapy has brought a new dawn for LUAD patients.
Linbin Hua, Jiyue Wu, Jiashu Ge, Xin Li, Bin You, Wei Wang, Bin Hu   +6 more
doaj   +1 more source