Results 21 to 30 of about 79,373 (295)

Xerotolerance: A New Property in Exiguobacterium Genus

Microorganisms, 2021
The highly xerotolerant bacterium classified as Exiguobacterium sp. Helios isolated from a solar panel in Spain showed a close relationship to Exiguobacterium sibiricum 255-15 isolated from Siberian permafrost.
María Castillo López, Beatriz Galán, Manuel Carmona, Juana María Navarro Llorens, Juli Peretó, Manuel Porcar, Luis Getino, Elías R. Olivera, José M. Luengo, Laura Castro, José Luís García   +10 more
doaj   +1 more source

HELIOS: High-speed sequence alignment in optics.

PLoS Computational Biology, 2022
In response to the imperfections of current sequence alignment methods, originated from the inherent serialism within their corresponding electrical systems, a few optical approaches for biological data comparison have been proposed recently.
Ehsan Maleki, Saeedeh Akbari Rokn Abadi, Somayyeh Koohi   +2 more
doaj   +1 more source

Regulatory T Cells from Patients with Rheumatoid Arthritis Are Characterized by Reduced Expression of Ikaros Zinc Finger Transcription Factors

Cells, 2022
Regulatory T (Treg) cells play an important role in immune tolerance and contribute to the prevention of autoimmune diseases, including rheumatoid arthritis (RA).
Mara Dittrich-Salamon, Anja Meyer, Shuaifeng Yan, Eva Steinbach-Knödgen, Konstantin Kotschenreuther, David Stahl, Carola tho Pesch, Joanna Schiller, Franziska Byrtus, Dorothee Jochimsen, Viktoria Golumba-Nagy, David M. Kofler   +11 more
doaj   +1 more source

Evaluation of a Fully Automated Antinuclear Antibody Indirect Immunofluorescence Assay in Routine Use

Frontiers in Immunology, 2020
Indirect immunofluorescence assay (IFA) using HEp-2 cells as a substrate is the gold standard for detecting antinuclear antibodies (ANA) in patient serum. However, the ANA IFA has labor-intensive nature of the procedure and lacks adequate standardization.
Hyun-Woo Choi, Yong Jun Kwon, Ju-Heon Park, Seung-Yeob Lee, Sejong Chun, Sejong Chun, Eun Jeong Won, Eun Jeong Won, Jun Hyung Lee, Hyun-Jung Choi, Hyun-Jung Choi, Soo Hyun Kim, Soo Hyun Kim, Myung-Geun Shin, Myung-Geun Shin, Jong-Hee Shin, Jong-Hee Shin, Seung-Jung Kee, Seung-Jung Kee   +18 more
doaj   +1 more source

Immune checkpoints in circulating and tumor-Infiltrating CD4 + T Cell Subsets in Colorectal cancer patients [PDF]

, 2019
Blockade of inhibitory immune checkpoints (ICs) is a promising therapeutic approach; however, it has shown limited success in some cancers including colorectal cancer (CRC). The tumor microenvironment (TME) is largely responsible for response to therapy,
Abu Nada, M, Al-Dhaheri, M, Elkord, E, Khawar, M, Murshed, K, Toor, SM   +5 more
core   +2 more sources

Co-Expression of TIGIT and Helios Marks Immunosenescent CD8+ T Cells During Aging

Frontiers in Immunology, 2022
Aging leads to alterations in the immune system that result in ineffective responsiveness against pathogens. Features of this process, collectively known as immunosenescence, accumulate in CD8+ T cells with age and have been ascribed to differentiation ...
Daan K. J. Pieren, Noortje A. M. Smits, Rimke J. Postel, Vinitha Kandiah, Jelle de Wit, Josine van Beek, Debbie van Baarle, Debbie van Baarle, Teun Guichelaar   +8 more
doaj   +1 more source

Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.

PLoS ONE, 2011
BackgroundAlthough in vitro IL-4 directs CD4 T cells to produce T helper 2 (Th2)-cytokines, these cytokines can be induced in vivo in the absence of IL-4-signalling. Thus, mechanism(s), different from the in vitro pathway for Th2-induction, contribute to
Karine Serre, Cécile Bénézech, Guillaume Desanti, Saeeda Bobat, Kai-Michael Toellner, Roger Bird, Susan Chan, Philippe Kastner, Adam F Cunningham, Ian C M Maclennan, Elodie Mohr   +10 more
doaj   +1 more source

Correlations between Circulating and Tumor-Infiltrating CD4⁺ Treg Subsets with Immune Checkpoints in Colorectal Cancer Patients with Early and Advanced Stages

Vaccines, 2022
The existence of various T regulatory cell (Treg) subsets in colorectal cancer (CRC) could play a variety of functions in the regulation of anti-cancer immunity.
Mohammad A. Al-Mterin, Khaled Murshed, Eyad Elkord   +2 more
doaj   +1 more source

Foxp3+Helios+ regulatory T cells are associated with monocyte subsets and their PD-1 expression during acute HIV-1 infection

BMC Immunology, 2019
Background Helios has been reported to stabilize regulatory T (Treg) suppressive function. Programmed cell death protein 1 (PD-1) expression in three human monocyte subsets modulates immune responses.
Lifeng Liu, Qiuyue Zhang, Peng Chen, Na Guo, Aixin Song, Xiaojie Huang, Wei Xia, Li Li, Christiane Moog, Hao Wu, Bin Su, Tong Zhang   +11 more
doaj   +1 more source

A novel biodegradable polymer-coated sirolimus-eluting stent: 1-year results of the HELIOS registry

Chinese Medical Journal, 2023
. Background:. The HELIOS stent is a sirolimus-eluting stent with a biodegradable polymer and titanium oxide film as the tie-layer. The study aimed to evaluate the safety and efficacy of HELIOS stent in a real-world setting. Methods:. The HELIOS registry
Bo Zheng, Yi Liu, Ruining Zhang, Wangwei Yang, Fangju Su, Rutao Wang, Dapeng Chen, Guidong Shen, Yumin Qiu, Lianmin Wang, Chang Chen, Zhongwei Wu, Fei Li, Jiayi Li, Chengxiang Li, Chao Gao, Ling Tao, for the HELIOS Investigators, Yanjie Yin, Xiuyuan Hao   +19 more
doaj   +1 more source