Results 1 to 10 of about 11,301 (222)

From Gut to Systemic Circulation: Molecular Strategies of Botulinum Neurotoxin Complexes [PDF]

Toxins
Botulinum neurotoxins (BoNTs), among the most potent biological toxins, rely on co-produced nontoxic proteins to survive harsh gastrointestinal conditions and achieve efficient systemic dissemination after oral exposure.
Juliette Mondy, Emmanuel Lemichez
doaj   +2 more sources

Laboratory approaches in desensitization for ABO-incompatible transplantation [PDF]

Clinical Transplantation and Research
ABO-incompatible transplantation, once considered contraindicated due to the risk of hyperacute rejection, has become a viable option owing to advances in immunosuppression and desensitization methods. Accurate measurement and effective reduction of anti-
Kyung-Hwa Shin, Hyun-Ji Lee
doaj   +2 more sources

An Update of Lectins from Marine Organisms: Characterization, Extraction Methodology, and Potential Biofunctional Applications

Marine Drugs, 2022
Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner.
Mirja Kaizer Ahmmed, Shuva Bhowmik, Stephen G. Giteru, Md. Nazmul Hasan Zilani, Parise Adadi, Shikder Saiful Islam, Osman N. Kanwugu, Monjurul Haq, Fatema Ahmmed, Charlene Cheuk Wing Ng, Yau Sang Chan, Md. Asadujjaman, Gabriel Hoi Huen Chan, Ryno Naude, Alaa El-Din Ahmed Bekhit, Tzi Bun Ng, Jack Ho Wong   +16 more
doaj   +1 more source

Human Immunity and Susceptibility to Influenza A(H3) Viruses of Avian, Equine, and Swine Origin

Emerging Infectious Diseases, 2023
Influenza A viruses (IAVs) of subtype H3 that infect humans are antigenically divergent from those of birds, horses, and swine. Human immunity against these viruses might be limited, implying potential pandemic risk. To determine human risk, we selected
Elien Vandoorn, Wojciech Stadejek, Isabel Leroux-Roels, Geert Leroux-Roels, Anna Parys, Kristien Van Reeth   +5 more
doaj   +1 more source

Porphyromonas gingivalis-Helicobacter pylori co-incubation enhances Porphyromonas gingivalis virulence and increases migration of infected human oral keratinocytes

Journal of Oral Microbiology, 2022
Background Porphyromonas gingivalis is part of the subgingival biofilm and a keystone species in the development of periodontitis. Interactions between P.gingivalis and other bacteria in biofilms have been shown to affect bacterial virulence ...
Cristopher Soto, Victoria Rojas, Lucas Yáñez, Antonio Hidalgo, Marcela Olivera, Martín Pacheco, Darna Venegas, Daniela Salinas, Denisse Bravo, Andrew F.G. Quest   +9 more
doaj   +1 more source

Conformational Variability Prediction of H5N1 Avian Influenza A Virus Hemagglutinins with Amino Acid Mutations Using SSSCPreds [PDF]

ACS Omega
Hiroshi Izumi, Laurence A. Nafie, Rina K. Dukor   +2 more
doaj   +2 more sources

Hemagglutinin Structure and Activities [PDF]

Cold Spring Harbor Perspectives in Medicine, 2020
Hemagglutinins (HAs) are the receptor-binding and membrane fusion glycoproteins of influenza viruses. They recognize sialic acid-containing, cell-surface glycoconjugates as receptors but have limited affinity for them, and, as a consequence, virus attachment to cells requires their interaction with several virus HAs. Receptor-bound virus is transferred
Steven J, Gamblin, Sébastien G, Vachieri, Xiaoli, Xiong, Jie, Zhang, Stephen R, Martin, John J, Skehel   +5 more
openaire   +2 more sources

Cloning, Expression, and Purification of the Recombinant Hemagglutinin of Human Influenza Virus H1N1 in the Eukaryotic Insect Cells Using Baculovirus Vector

مجله دانشکده پزشکی اصفهان, 2020
Background: The H1N1 influenza virus is a highly pathogenic virus that threatens human life. Vaccination is an effective way of preventing and controlling influenza.
Niloufar Rashedi, Morteza Taghizadeh, Parisa Mohamadynejad, Mehdi Mahdavi, Reza Jalalirad   +4 more
doaj   +1 more source

Influenza Virus Infection Induces a Narrow Antibody Response in Children but a Broad Recall Response in Adults

mBio, 2020
In contrast to influenza virus vaccination, natural infection induces long-lived and relatively broad immune responses. However, many aspects of the antibody response to natural infection are not well understood.
Philip Meade, Guillermina Kuan, Shirin Strohmeier, Hannah E. Maier, Fatima Amanat, Angel Balmaseda, Kimihito Ito, Ericka Kirkpatrick, Andres Javier, Lionel Gresh, Raffael Nachbagauer, Aubree Gordon, Florian Krammer   +12 more
doaj   +1 more source

Insight into highly conserved H1 subtype-specific epitopes in influenza virus hemagglutinin [PDF]

, 2014
Influenza viruses continuously undergo antigenic changes with gradual accumulation of mutations in hemagglutinin (HA) that is a major determinant in subtype specificity.
Cho, Ki Joon, Hong, Kwang W, Kim, Kyung Hyun, Kim, Se-Ho, Kim, Sella, Lee, Ji-Hye, Saelens, Xavier, Seok, Jong Hyeon   +7 more
core   +9 more sources